On this week's episode, @digiglean.bsky.social and I talk about Pluggy, subprocess, type checkers, and more. With content from: @djangoproject.com @pydatalondon.bsky.social @simonwillison.net @pyodide.org @haleshot.bsky.social and others not on the 🦋

Episode #301: Running Python Locally in a Sandbox – The Real Python Podcast

How do you avoid the risk of running a Python application locally that could be malicious, break your code, or leak private data? How can you create a sandboxed local environment using WASM and…

buff.ly

Pyodide 314.0.0 is out! 🎉 This marks a significant milestone for the Python-in-the-browser ecosystem! PEP 783 has been accepted, so Pyodide wheels can now be published directly to PyPI 🐍📦 blog.pyodide.org/posts/314-re... Thanks to @pydantic.dev for their guide: pydantic.dev/articles/ems...

Pyodide 314.0.0 is out! 🎉 This marks a significant milestone for the Python-in-the-browser ecosystem! PEP 783 has been accepted, so Pyodide wheels can now be published directly to PyPI 🐍📦 blog.pyodide.org/posts/314-re... Thanks to @pydantic.dev for their guide: pydantic.dev/articles/ems...

Just gave a talk #ATScience on open-source science + Pyodide + computational notebooks. @sazeka.bsky.social and I wrote a review on data science education in HS and HE in the US with some examples of good models from around the world.

5/ 🤖 AI & local LLMs in browser We integrate @langchain.bsky.social , MLC Web LLM for on-device inference, TensorFlow.js for embeddings & @pyodide.org for Python logic : all running directly within your browser.

Unified stack inspired by work with @pyodide.org and webR teams, builds a whole ecosystem for Python, R, C++, Javascript, and Octave (open-source Matlab).

{livelink} walked so {webrarian} could run. Mini browser-based #rstats environments powered by #webR and its 4-panel editor. YAML config, build, preview. Done. R package coming soon. #pyodide folks, stay tuned.

Another mini-milestone ... now I can publish Jupyter Lite Python notebooks (using Pyodide/WASM) onto hex.camp locations ... here's a demo that extracts the OpenStreetMap data for the cities that make up Metro Vancouver 6kg6rweynwea.vanhex.ca/lab/index.ht...

Are interactive essays the future of education? I asked Claude Code to build an interactive essay for PCA + SVD that works client side. Notice how python code executes and graphs are generated WITHOUT any backend! Play with it yourself 👇

WebAssembly opened the door for Python on the web, but Pyodide pushed it all the way open. Read insights from Jessica Wachtel on running uncompromised Python client-side.

Run Real Python in Browsers With Pyodide and WebAssembly

Pyodide compiles CPython to WebAssembly, letting developers run full Python directly in the browser without servers or installations.

thenewstack.io

I've been working on a universal metrics layer for @sidequery.dev the past few months that works with many different semantic layer formats. I built a demo so you can try it out. Runs 100% in the browser (via DuckDB & Pyodide). Warning large download !

Sidemantic Metrics View Demo

Interactive demo of Sidemantic metrics visualization with OpenRTB auction data.

sidemantic.com

🧪 I'm happy to share a new preprint that @sazeka.bsky.social and I recently submitted through our work with @gothamdataclinic.org. It's a review of tools, infrastructure, and training needed to broaden data science education in high school and higher education. #datascience #education #opensource

TIL how to add notebook cells running on @pyodide.org to Quarto projects, such as my blog: alonsosilvaallende.github.io/til/posts/20... It's very easy to change the Pyodide version if needed. Thanks @coatless.bsky.social for this great Quarto extension

*laughs maniacally* I hacked my personal website into an executable Python (Marimo) notebook*, powered by Pyodide (WASM), running in a container on a Raspberry Pi cluster sitting in my closet.

On the PSF Blog: A summary of the "Upstreaming the Pyodide JavaScript FFI" talk by Hood Chatham during the #Python Language Summit at #PyConUS 2025

The Python Language Summit 2025: Upstreaming the Pyodide JS FFI

The final talk presented at the Language Summit was given by Hood Chatham, who maintains the Pyodide project and is trying to make fetch() happen for Python (among many other JavaScript APIs).

pyfound.blogspot.com

🌐 New blueprint: AI agents that run in your browser via Webassembly & Pyodide. Just open an HTML file and go. They work with OpenAI API compatible models or local models via Ollama/vLLM. Take a look : github.com/mozilla-ai/wasm-agents-blueprint

GitHub - mozilla-ai/wasm-agents-blueprint: Testing WASM-powered AI agents

Testing WASM-powered AI agents. Contribute to mozilla-ai/wasm-agents-blueprint development by creating an account on GitHub.

github.com

Experience the future of large-scale data processing without leaving your browser window.

Blosc Development Team@blosc.org · last yr.

#Blosc2 now runs directly in your browser! Leveraging the power of #WASM, #Pyodide, and #JupyterLite, you can harness efficient, adaptable compression through the web's universal interface. Compress Better, Compute Bigger, Share Faster #WebAssembly #DataCompression #WebDevelopment #DataScience

#Blosc2 now runs directly in your browser! Leveraging the power of #WASM, #Pyodide, and #JupyterLite, you can harness efficient, adaptable compression through the web's universal interface. Compress Better, Compute Bigger, Share Faster #WebAssembly #DataCompression #WebDevelopment #DataScience

🌟 Spotlight on @hlondogard.bsky.social! Detect objects in-browser — zero servers. Hampus’s marimo notebook uses @pyodide.org to proxy transformers-js-py and onnxruntime for on-device DETR — upload an image or URL for instant bounding boxes. Try it live → marimo.io/p/@hlondoga...

Day 27 of #MeetTheMaintainers Say hello to @pyodide and Agriya Khetarpal (https://github.com/pyodide/pyodide) Pyodide runs real Python, not watered down, not rewritten, in the browser, with support for scientific libraries and everything. Started at Mozilla, now […] [Original post on mas.to]

💡Pyodide is making Python documentation interactive! From his PyCon India talk, @agriyakhetarp.al demonstrates how @pyodide.org transforms NumPy and SciPy docs with browser-based execution. 📽️ www.youtube.com/watch?v=H44x... #PyconIndia #ScientificPython #Pyodide

Python in the browser: enhancing the Scientific Python ecosystem's interoperability with Pyodide

YouTube video by Python India

youtube.com

@pytorch.org and @pyodide.org are on bluesky ❤️ Added to the pydata starter pack: go.bsky.app/6HkrMcp

import micropip; await micropip.install("bluesky") We're finally on Bluesky! Whether you're coming to this post from another social media platform or not; why not repost this, give us a follow, and tag us in your posts around Python and WASM! We truly love it when you do! 🥰