Registrations are open for our 7th annual congress « Childhood Cancers: Understand to treat ». It will be held in Lille in October and the scientific program is taking shape. Registration & accommodations are free for students non-permanent scientists of the network, as always. Spread the word 🙏

📣 Youth4Kids 2025 🎗️ @r4knetwork.bsky.social This morning, we had the pleasure to welcome Dr Clara Savary from @hmriaustralia.bsky.social. She is currently working on deciphering the resistance mechanisms of ONC201 in DIPG. Well done Clara and the whole team led by Dr Matt Dun. 👏

📣 Youth4Kids 2025 🎗️ Let's start with @guixe-m.bsky.social from @irbbarcelona.org. Her work focuses on the origin of second malignancies in children or the factors underlying the response to immunotherapies. Looking forward to listening to her talk! @r4knetwork.bsky.social

It is that time of the year again ! Our annual seminar dedicated to the young generation of cancer researchers is starting now. Four keynote lectures and dozens of presentations from early-career scientists. This is going to be a hoot as usual 🥳

In this week’s publication highlights, we picked this study just out @naturemedicine.bsky.social describing an innovative method for the rapid classification of brain tumors based on molecular profiling. Congrats to all involved @dkfz.bsky.social and beyond 👏🏻 www.nature.com/articles/s41...

Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors - Nature Medicine

Application of a nanopore sequencing workflow for real-time analysis of brain tumors results in molecular classification within a 30-minute intraoperative window, followed by comprehensive profiling w...

nature.com

NEW PUBLICATION! Researchers from the @r4knetwork.bsky.social just revealed the progressive chromatin rewiring induced by the ETO2::GLIS2 fusion in the onset of pediatric leukemia. A collaboration between @gustaveroussy.fr, @institutimagine.bsky.social, & many more. doi.org/10.1182/bloo...

In our weekly update, we highlighted this study by Peter Houghton and colleagues at @uthealthsa.bsky.social addressing the challenging question of resistance to radiotherapy in pediatric brain tumors. Just out in @neuroonc.bsky.social ⤵️

Eddy Pasquier 🧪🇫🇷🇦🇺@eddpasquier.bsky.social · last yr.

Researchers @uthealthsa.bsky.social just published an interesting study in @neuroonc.bsky.social showing that radio-resistance in pediatric BRAFV600E gliomas is associated with an up-regulation in MAPK & PI3K/mTOR signaling, which can be therapeutically exploited. academic.oup.com/neuro-oncolo...

In this week’s newsletter, we highlighted this study just out in @neuroonc.bsky.social. Using high-resolution proteomics, Poul Sorensen and colleagues attempted to improve biology-driven risk stratification and therapy assignment for #medulloblastoma patients. academic.oup.com/neuro-oncolo...

High-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor

AbstractBackground. While international consensus and the 2021 WHO classification recognize multiple molecular medulloblastoma subgroups, these are difficu

academic.oup.com

I hope there will be hundreds of marches around the world to stand up for science tomorrow. Let’s show these monsters, we won’t let them destroy Science. Killing research is killing hope.

Our free webinars are back! Today we had the pleasure of listening to Dr Ulrich Schüller from the Research Institute Children’s Cancer Center Hamburg, talking about his work on the molecular diversity of spinal ependymomas.