Rob Denton

@rddenton.bsky.social

Bio Professor | scientist (genomics, evolution, conservation), educator, perpetual student | he/him | posts don't represent employer | dentonlab.org

Kayhani et al. find that introgression of warm-adapted alleles was largely successful despite the risk of introducing mitonuclear incompatibilities that could result from genome-wide shifts toward the paternal allele in Tigriopus californicus. 🔗 doi.org/10.1093/molbev/msag158 #societyjournal

Introgression of thermal tolerance alleles drives adaptation despite risk of mitonuclear conflict

Abstract. Hybridization may offer a form of genetic rescue from warming temperatures through the introgression of heat-adapted alleles from a high-toleranc

doi.org

Finally posted an ad for the postdoc position on my new NSF-funded project—come help build a new method to study plants' responses to environmental variation in space and over time, and figure out interesting ways to use it! Apply by 23 August to ensure consideration. Details: buff.ly/qTvaqvD

Hey team - it’s looking very likely that I’ll be hiring not one but two four year postdocs! We’re a fun lab with tons of theoretical and applied pop gen projects - broadly in polyploid, conservation, and human evo. Competitive salary, sunny San Diego! Do share with your about to defend grads!

Our new genome annotation method relies almost entirely on transcriptome and alignment evidence, and as a result outperforms pretty much all other de novo pipelines. Check out the just-published paper led by Aleksey Zimin: rdcu.be/frSOg

Efficient evidence-based genome annotation with EviAnn

Nature Methods - EviAnn surpasses existing genome annotation methods by leveraging gene expression and protein sequence homology evidence to achieve higher accuracy and efficiency.

rdcu.be

If you are attending #JMIH26 in New Orleans, please consider participating in the mentorship program! This is a *huge* thing for helping first time attendees and growing networks. If you missed it during registration, here is a form for participants (mentors and mentees): forms.gle/ERLGdXdQavzo...

2026 SSAR/JMIH Mentorship Program interest form

The SSAR Mentorship Program has become an important way for meeting attendees to make lasting professional connections. Each mentor is usually matched with 1-2 mentees and given a list of ideas for ...

forms.gle

Dispatches from the lab: outside world is insane, but lab environment is wonderful: fun/rowdy group, lots of support, many interesting projects, ton of learning. Thankful for this job, the $ support to make the science go, and for the privilege to fight for it. Call your reps folks, organize.

A shelf for food and drinks outside of a science lab, showing a diversity of water bottles and lunchboxes, most adorned with playful stickers

If you are interested in collecting specimens for chromosomal genomes and/or generating chromosomal reference genomes from specimens that were not cold-chain preserved, please read on and share this thread.

[new paper!] All-female, polyploid salamanders are weird: they have 3-4 sets of giant chromosomes, a mitochondria that doesn't match their nuclear genomes, and are made of fewer, bigger cells. We've thought about the consequences of this in lots of ways, stumbling on a neat one during my PhD..(1/n)

Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. https://scim.ag/4nTQ3nq

How animals sense Earth’s magnetic field is one of biology’s enduring mysteries. Researchers have now identified superparamagnetic macrophages in the livers of rock pigeons (Columba livia) to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation.

Photo: Andreas Teichmann/laif/Redux