Kauro, a graph-based chatbot for high-fidelity information transmission conversations https://www.medrxiv.org/content/10.64898/2026.01.30.25342358v1
Jonathan LoTempio
@realjlo.bsky.social
Fellow in the bioethics of human data at Penn. Bioinformatics, ethics, policy, and science. Interested in making pangenomes and how human data flows.
New out in @natgenet.nature.com - The bankruptcy of #23andMe put #human #genetic #data at risk of #enclosure. Under the new #23andMeResearchInstitute, data remain available. Read me, @jonathanmoreno.bsky.social et al on lessons for next time: www.nature.com/articles/s41... @ucirvine.bsky.social
Impact of the 23andMe bankruptcy on preserving the public benefit of scientific data - Nature Genetics
The bankruptcy of 23andMe was an inflection point for the direct-to-consumer genetics market. Although the privacy of consumer data has been highlighted by many as a concern, we discuss another key te...
nature.com
🧵1/4: 'Such a trove of data may be put to good use... The firm “did an incredible thing in that they got people to pay to participate in research”, says Jonathan LoTempio, of @upenn.bsky.social . 100s of studies have drawn on 23andMe.' www.economist.com/business/202...
How safe is your DNA in a bankruptcy?
23andMe’s demise raises thorny legal questions
economist.com
Funding for science should not be a partisan issue. wapo.st/41UWFHA
Opinion | Funding for R&D isn’t a gift to academia
Investing in scientific research and development is vital to U.S. security.
wapo.st
Califf nails it: “It’s despicable to treat fellow human beings this way and a sign of immaturity of the people doing it" F.D.A. Reinstates Fired Medical Device, Food and Legal Staffers www.nytimes.com/2025/02/24/s...
F.D.A. Reinstates Fired Medical Device, Food and Legal Staffers
The agency changed course just days after firing employees who oversee the safety of food and life-sustaining medical devices. Dozens of workers said they and others were back at work Monday.
nytimes.com
OPM is planning to fire all employees on probation (less than one year of employment). Agencies have until noon on Wednesday to submit a list of probationary employees to the OPM and indicate whether they wish to retain them—though it has been stated that this will not make a difference.
What do you mean when you say that you've #shared your #data broadly? @jonathanmoreno.bsky.social and I published a new data sharing framework in @naturegenet.bsky.social along with #bioethics challenges for #genomics in the #ai era. www.nature.com/articles/s41... @pennmedresearch.bsky.social
Overcoming challenges associated with broad sharing of human genomic data - Nature Genetics
This Perspective discusses the definitions of ‘broad’ that have been used in the context of sharing of human genomic data and proposes a clarified and reformed terminology for describing genomic data ...
nature.com
🚨 Excited to announce the Marker paper for the GREGoR Consortium! arxiv.org/abs/2412.14338 Accelerating #RareDisease diagnostics with cutting-edge #Genomics and global data sharing of omics and deep phenotyping from ~7500 individuals on NHGRI AnVIL and much more to come! 🧬
GREGoR: Accelerating Genomics for Rare Diseases
Rare diseases are collectively common, affecting approximately one in twenty individuals worldwide. In recent years, rapid progress has been made in rare disease diagnostics due to advances in DNA seq...
arxiv.org