How much do algorithmic and experimental choices drive the accuracy of reconstructing tumour evolution? In this Cancer Research commentary, @zaccasimo.bsky.social and I discuss a recent Nature Biotech benchmarking paper exploring this question: bit.ly/3VAMRQs
Tumor Evolution Reconstruction Is Heavily Influenced by Algorithmic and Experimental Choices
Tumor progression is an evolutionary process during which cells acquire distinct genetic alterations. Several cancer evolutionary studies reconstruct this evolutionary process by applying bulk DNA seq...
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