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Harvard_MCB@harvardmcb.bsky.social · last wk.

MCB Junior Fellow Wins Two Prestigious Evolutionary Science Awards— First Dual Honor in 25 Years 🧪 🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @wendyssae.bsky.social @nbellono.bsky.social @naoshigeuchida.bsky.social @harvard.edu @sse-evolution.bsky.social @eseb.bsky.social

MCB Junior Fellow Wins Two Prestigious Evolutionary Science Awards— First Dual Honor in 25 Years - Harvard University - Department of Molecular & Cellular Biology

Wendy Valencia-Montoya, a Junior Fellow in the Harvard Society of Fellows affiliated with the lab of MCB Professor Nick Bellono, has been awarded two of the most coveted […]

mcb.harvard.edu

@rnett42.bsky.social · last mo.

In our new preprint, we report how clubmoss plants use an ancient biosynthetic pathway (>300 million years old!) to make huperzine A, an alkaloid with potential as a treatment for Alzheimer's disease. Great work by Eric Fields and @cyhkim.bsky.social www.biorxiv.org/content/10.6...

Ancient origins of alkaloid biosynthesis in medicinal clubmosses

The plant kingdom is rich with medicinal natural products that are complex and difficult to access. Discovering how plants build these molecules can be challenging, especially for biosynthetic pathway...

biorxiv.org

Lichman Lab@lichmanlab.bsky.social · 3mo ago

Pleased to share our full publication of our manuscript describing completion of nicotine biosynthesis in @natcomms.nature.com following our pre-print from December last year. In this work we solve the 200-year-old puzzle of how tobacco plants make nicotine. www.nature.com/articles/s41...

Nicotine biosynthesis is completed by cryptic activating glucosylation - Nature Communications

Despite the significance of nicotine, a neuroactive alkaloid produced by tobacco, its biosynthesis has remained elusive. Here, the authors report the in vitro and in planta reconstruction of a fo...

nature.com

Harvard_MCB@harvardmcb.bsky.social · 5mo ago

Common Plant Proteins Found to Calm the Immune System 🧪 🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @microbiometcell.bsky.social @rachellegaudet.bsky.social @dulaclab.bsky.social @rivaselenarivas.bsky.social @science.org @harvard.edu

Common Plant Proteins Found to Calm the Immune System - Harvard University - Department of Molecular & Cellular Biology

A new study co-led by MCB’s Kazuki Nagashima and published in Science Immunology (PDF) identifies plant-derived molecules that help quiet the immune system, preventing inflammatory reactions to the […...

mcb.harvard.edu

Harvard_MCB@harvardmcb.bsky.social · 5mo ago

Wendy Valencia Montoya Receives Weintraub Graduate Student Award for Groundbreaking Thesis on the Evolution of Sensory Worlds 🧠 🧪🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @nbellono.bsky.social @rachellegaudet.bsky.social @basicsci.fredhutch.org @harvardoeb.bsky.social

Wendy Valencia Montoya Receives Weintraub Graduate Student Award for Groundbreaking Thesis on the Evolution of Sensory Worlds - Harvard University - Department of Molecular & Cellular Biology

Wendy Valencia Montoya has been named a recipient of the prestigious 2026 Harold M. Weintraub Award in recognition of her doctoral thesis, an ambitious and interdisciplinary body of […]

mcb.harvard.edu

@rnett42.bsky.social · 6mo ago

Really grateful to receive support from the George W. Merck Fellowship! Through this award, we will uncover how plants synthesize complex neuroactive molecules that are important for both plant biology and human health. bsky.app/profile/harv...

Harvard_MCB@harvardmcb.bsky.social · 6mo ago

Ryan Nett Awarded 2025–27 George W. Merck Fellowship 🧪 🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @nbellono.bsky.social @rachellegaudet.bsky.social @dulaclab.bsky.social @microbiometcell.bsky.social @cryptogenomicon.bsky.social @jeeyunc.bsky.social @zombiflied.bsky.social

Lichman Lab@lichmanlab.bsky.social · 7mo ago

So pleased to share this work on alkaloid biosynthesis. Great collaboration with @unsworthchem.bsky.social. Well done to all authors. We have found key alkaloid producing enzymes that look like those normally found in bacteria. www.york.ac.uk/news-and-eve...

Plant discovery could lead to new ways of producing medicines

Scientists have shown how plants produce powerful natural chemicals that could help in the production of new medicines in more environmentally friendly ways.

york.ac.uk

New Phytologist@newphyt.bsky.social · 7mo ago

Parallel evolution of plant alkaloid biosynthesis from bacterial-like decarboxylases Wood et al. nph.onlinelibrary.wiley.com/share/HYPKAP...

Basic amino acid-derived alkaloids.
Lichman Lab@lichmanlab.bsky.social · 8mo ago

The centuries old mystery of how tobacco plants make nicotine has a sweet solution: an additional glucose group is vital for the key pathway steps. Read more in our pre-print: www.biorxiv.org/content/10.6.... Incredible work from @benschwabe.bsky.social and collaborators in York and Copenhagen.

Nicotine biosynthesis completed by cryptic activating glucosylation

Nicotine is a neuroactive alkaloid produced by tobacco (Nicotiana tabacum) as a defense against herbivory, and an addictive stimulant that has been used by humans for millennia. Despite its significan...

biorxiv.org

@rnett42.bsky.social · 11mo ago

Thanks to Dr. Cassandra Quave for hosting me on her Foodie Pharmacology podcast! We discussed the molecules responsible for the properties of medicinal plants - and how my lab studies the chemistry that plants use to make them. Check it out! t.co/nEdpoyN8QD

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Harvard_MCB@harvardmcb.bsky.social · 12mo ago

Ryan Nett Named Pew Scholar for Innovative Research on Plant-Derived Molecules 🧪 🧬 #AcademicSky #higherEd www.mcb.harvard.edu/department/n... @rachellegaudet.bsky.social @dulaclab.bsky.social @zombiflied.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social @neurovenki.bsky.social

Ryan Nett Named Pew Scholar for Innovative Research on Plant-Derived Molecules - Harvard University - Department of Molecular & Cellular Biology

MCB faculty member Ryan Nett has been named a 2025 Pew Scholar in the Biomedical Sciences, one of 22 early-career scientists selected nationwide for their promising and innovative […]

mcb.harvard.edu