Really great state-of-the-art talk by Julia Riedl on the role of podoplanin in brain cancer-assiciated thrombosis #ISTH2025
Betül Ünlü
@betulunlu.bsky.social
Postdoc at RCSI Dublin. Interested in crosstalk between coagulation factors and cancer. With VWF and Tissue Factor as my pet proteins 🐶😻
Fantastic talk by Gemma Leon on TF+ Tcell population in inflammatory bowel disease @rogerpreston.bsky.social @rcsi.bsky.social #ISTH2025
Elegant study to study TF/FVII/FX structures on nanodisks with higher CryoEM resolution to propose a mechanism for TF encryption/decryption by Josepha Sedzro @jhmorrissey.bsky.social
Microvasculature-on-a-chip, there are too many cool applications for which this can be inplemented. Fantastic talk by @wilburlam.bsky.social #ISTH2025
Very exciting talk on how VWF activity is dysregulated, as IL6 inhibits ADAMTS13 in ischemic stroke. After clot formation the vessels can reverses blood flow to protect the brain cells. @frederikdenorme.bsky.social #ISTH2025
Timon discussed how ADAMTS13 interacts with macrophage scavenger receptors #ISTH2025 @rcsi.bsky.social @jsodonnell.bsky.social
Great work by Hoberstorfer from Vienna 👏Unfortunately, machine learning of #cancer-associated thrombosis prediction didn’t outperform current models. Showing how complex CAT is #ISTH2025 @cihanaymd.bsky.social
Great way to measure (coagulation) protein profiles in plasma using quantitative protein mass spectrometry, talk by Bart van Vlijmen #ISTH2025
#ISTH2025 day 1 is officially finished. Had a great time with old and new friends with an amazing view over Washinton 🥰 @fib390-396a.bsky.social @tffviia.bsky.social
Lovely to see my former colleagues from my PhD lab up on the screen during the opening ceremony of #ISTH2025 by ISTH president Prof Angchaisuksiri #LUMC #Thrombosis&Hemostasis
Alain chion delivered an excellent talk on how type2b VWD mutants can induce enhanced clearing of VWF @jsodonnell.bsky.social @rcsi.bsky.social
Kicking off #ISTH2025 with the first falk from RSCI by @aislingrehill.bsky.social on fibrin on trained immunity-associated myeloid cell hypercoagulability @rogerpreston.bsky.social @rcsi.bsky.social
We're looking for a #researchassistant If you enjoy being involved in translational research and clinical trials then take a 👀 @mcrcnews.bsky.social @uniofmanchester.bsky.social #RadNet www.jobs.manchester.ac.uk/Job/JobDetai...
Research Assistant in Translational Radiobiology:CRUK Oglesby Cancer Research Building, 555 Wilmslow Road, M20 4GJ
jobs.manchester.ac.uk
Enhanced myeloid cell hypercoagulability is a maladaptive consequence of trained immunity www.science.org/doi/10.1126/...
Also, we are looking to recruit a new postdoc asap to a funded position in our lab in Dublin. Please check out our lab website prestonlab.ie for what we do, and get in touch if interested.
Preston Labs
prestonlab.ie
Pleased to share our latest paper in Science Advances on myeloid cell ‘trained hypercoagulability’! 🚀 Project led by @aislingrehill.bsky.social - huge thanks to our collaborators & funders @tcddublin.bsky.social @researchireland.bsky.social CHI and HRB Ireland tinyurl.com/df4fsrrx
Trained immunity causes myeloid cell hypercoagulability
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TF/FVII/PAR2 complex is like a diet for macrophages, with no munching of breast cancer cells Intrigued? Check out our commentary ‘Engulfed in complexity’ on macrophage phagocytosis in breast cancer (by Gosh et al.) in @jthjournal.bsky.social JamieO’Sullivan @rcsi.bsky.social shorturl.at/Wl57T
shorturl.at
New publication from our group in @naturecomms.bsky.social led by Gemma Leon @rcsi.bsky.social Thanks to our collaborators at @tcddublin.bsky.social, CHI Crumlin, and to @researchireland.bsky.social and Children’s Health Ireland for funding. Open access link: rdcu.be/d93ds
Tissue factor-dependent colitogenic CD4+ T cell thrombogenicity is regulated by activated protein C signalling
Nature Communications - Patients with inflammatory bowel disease (IBD) have increased risk for venous thromboembolism, but mechanistic insight is still lacking. Using both mouse experimental...
rdcu.be
Fantastic poster presentation by Neha on #VWF in #breastcancer during the first day of #BSHT and #nvth #O’SullivanLab @rcsi.bsky.social
Little Rudolph has payed me a visit to guide me (and bring good 🍀!) through my final experiment of 2024! Thank you sectret Santa for this cute surprise 🥰 @rcsi.bsky.social
Just in case you missed it on X: aggressive #breastcancer on #thrombosis in a hypercoagulable mouse model. Interesting insights on cancer-associated thrombosis #VTEsky #thrombosky #onsky #cansky #medsky tinyurl.com/y8d4ytx7 @tromboseleiden.bsky.social x.com/henriverstee...
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