Roshani Badgami

@roshanib.bsky.social

Researcher at the John Innes Centre searching for wheat resistance to Fusarium Head Blight British-Nepali 🇳🇵(she/her)

Had such fun organising the sold-out Ticket Launch event at the Warwick Arms last week! Big thanks to Jonathan Kirby and Rebecca Casson for speaking and co-organisers Amy and Victoria! The Norwich speakers this year look fantastic, definitely worth grabbing tickets while they are available!!

Pint of Science UK@pintofscience.uk · 4mo ago

✨Tickets for #pint26 are now on sale!✨ 🎟Book here 👉 pintofscience.co.uk 👈 🗓18-20 May 2026 📍45+ locations across the UK 🗣Nearly 450 events

New Preprint: A stage-resolved map of dynamic septin interactions required for infection by the rice blast fungus (2026) https://www.tsl.ac.uk/publications/166266

bioRxiv: A stage-resolved map of dynamic septin interactions required for infection by the rice blast fungus (2026)

Septin GTPases are essential cytoskeletal regulators that organize membranes and scaffold protein complexes to control cytokinesis, polarity, and morphogenesis. How septins execute these functions remains poorly understood, and comprehensive, stage-resolved interaction maps are lacking. Here, we define a quantitative, time-resolved septin interactome in the rice blast fungus Magnaporthe oryzae using immunoprecipitation coupled to mass spectrometry. We map more than 350 interactors of septins Sep3, Sep4, Sep5 and Sep6, revealing a dynamic network required for appressorium-mediated plant infection. Beyond canonical roles in cytoskeletal organisation and polarity, septins associate with proteins linked to membrane remodelling, metabolism, and virulence, deployed during host invasion. Integration with ultra-high-throughput yeast two-hybrid analysis defines a high-confidence septin interactome and identifies previously uncharacterised factors, including Msi1, a BAR domain protein required for invasive growth. Together, these findings establish septins as dynamic organisers of infection-related processes and provide a framework for understanding how cytoskeletal scaffolds coordinate fungal pathogenesis.

doi.org

In October 2026 we held our second Black in Plant Science (BiPS) Conference at the University of Leeds. We asked the members of our community why BiPS is important to them, and here is what they had to say: buff.ly/OClLBP3 Thank you to everyone who contributed to this video.

The Importance of the Black in Plant Science Network

In October 2026 we held our second Black in Plant Science (BiPS) Conference at the University of Leeds. We asked the members of our community why BiPS is im...

youtu.be

Did you know 1 m^2 of wheat only produces enough grain for one loaf, and the UK buys 11M loaves every day?! I loved chatting about the importance of making resilient wheat at the "Future of Farm and Agriculture" Farmers Weekly at New Scientist Live! Thanks Shannon Woodhouse for organising! 🌾

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