This is a new paper testing Bayesian computational mechanisms of improvements in cardiac interoception due to a training program developed by @sarahgarf.bsky.social and colleagues. Led by a very talented grad student @chatrins.bsky.social (www.sciencedirect.com/science/arti...)

A hierarchical Bayesian model reveals increased precision weighting for afferent cardiac signals, and reduced anxiety, as a function of interoceptive training

Interoceptive interventions offer a promising avenue for improving mental health conditions, which commonly feature bodily or interoceptive symptoms. …

sciencedirect.com

Congrats to Navid on his new paper in Molecular Psychiatry! Computational modeling found that learning rates and uncertainty sensitivity could distinguish between affective disorders and substance use disorders. Forgetting rate was instead affected transdiagnostically. www.nature.com/articles/s41...

Computational mechanisms of learning and forgetting differentiate affective and substance use disorders - Molecular Psychiatry

Molecular Psychiatry - Computational mechanisms of learning and forgetting differentiate affective and substance use disorders

nature.com

We’re bringing computational psychiatry to #ACNP2026 Our panel shows how RL, DDMs, active inference, and neural models can unpack symptom heterogeneity across anxiety, psychosis, ADHD, depression, and suicide risk-moving beyond diagnoses to mechanisms. @acnporg.bsky.social #ComputationalPsychiatry

🧠📈 How can computational models help decode interoception in #MentalHealth? This chapter explores how sensing the body’s internal signals links to psychiatric disorders— how computational psychiatry may unlock new treatment targets. bit.ly/4p8wjLE @rssmith.bsky.social @mpwpaulus.bsky.social

This is ‘Really’ FUTURISTIC!! #MentalHealth I would be Soo ‘Honored’ to Help in anyway EvenIF ‘That way’ is By SHARING these Advancements!!! @rssmith.bsky.social @mpwpaulus.bsky.social

Springer@springer.springernature.com · 8mo ago

🧠📈 How can computational models help decode interoception in #MentalHealth? This chapter explores how sensing the body’s internal signals links to psychiatric disorders— how computational psychiatry may unlock new treatment targets. bit.ly/49cjj2P @rssmith.bsky.social @mpwpaulus.bsky.social

📣We are excited to welcome @rssmith.bsky.social for our next CCP Speaker Series talk! Join us TODAY, November 21st, at 1pm EDT Register HERE for the Zoom Link 👉https://docs.google.com/forms/d/e/1FAIpQLSfA-SAlxM8jP0D9V-tu_fMEK_SeFzhN7HrnG9lrBM8V3UInGA/viewform?usp=header

Very excited to be attending #IWAI2025 in Montreal🍁 organised by David Benrimoh!! already heard some great talks by @rssmith.bsky.social and team 🧠💡

Even after recovery, relapse is heartbreakingly common in anorexia nervosa. Could the answer lie in the gut’s hidden signals? 🧵

Big congrats to Marishka on this. I know how much time and effort went into it. Really happy to see it out! For those interested, she replicated prior longitudinal results using an approach-avoidance conflict task and showed how model parameters afforded out-of-sample clinical prediction.

Computational Psychiatry@cpsyjournal.bsky.social · 11mo ago

New paper in CPsy - 'Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders' from Marishka Mehta and the group of @rssmith.bsky.social doi.org/10.5334/cpsy...

Agreed. The video examples are super interesting. I wish the questions were asked in a more controlled way, but I can’t fault for some limitations of this rarely possible type of work. It seemed quite somatic and abrupt. No spontaneous descriptions of emotion proper either. Only when given a word.

Nicole Rust@nicolecrust.bsky.social · last yr.

(buried in a reply, but) This is mind-blowing & deserves a post. Scroll to "video" in this article to watch what happens when the human hypothalamus is stimulated: it's a combo of embarrassment/shame and intense body sensations emanating from the heart. WOW. www.brainstimjrnl.com/article/S193...

Computational modeling revealed that individuals with methamphetamine use disorder show reduced information-seeking and slower belief updating when trying to maximize long-term reward. @torutakahashi.bsky.social @rssmith.bsky.social www.nature.com/articles/s44...

Individuals with methamphetamine use disorder show reduced directed exploration and learning rates independent of an aversive interoceptive state induction - Communications Psychology

Computational modeling revealed that individuals with methamphetamine use disorder show reduced information-seeking and slower belief-updating when trying to maximize long-term reward. This might crea...

nature.com

Congratulations to @torutakahashi.bsky.social and Carter Goldman on their newly published paper! This paper shows that individuals with methamphetamine use disorder show reduced directed exploration and slower dynamic learning rates in both high/low anxiety states www.nature.com/articles/s44...

Individuals with methamphetamine use disorder show reduced directed exploration and learning rates independent of an aversive interoceptive state induction - Communications Psychology

Computational modeling revealed that individuals with methamphetamine use disorder show reduced information-seeking and slower belief-updating when trying to maximize long-term reward. This might crea...

nature.com

I am so excited to share that our paper 'A neural basis for distinguishing imagination from reality' is now published in @cp-neuron.bsky.social! 🧠✨ See thread below! doi.org/10.1016/j.ne...

Nadine Dijkstra@nadinedijkstra.bsky.social · 2y ago

I am beyond excited to share our new preprint ‘A neural basis for distinguishing between imagination and reality’ with Thomas von Rein, @peterkok.bsky.social and @smfleming.bsky.social! osf.io/preprints/ps... a thread 🧵

this is excellent - congratulations! In particular nice to see the very robust basic pruning behavioural effect replicate in this version of the task (originally designed for the scanner). It seems that pruning may end up being more relevant to SUD than MDD, @docqhuys.bsky.social!

Thank you @clairelavalley.bsky.social and @rssmith.bsky.social. Striking to see aversive pruning altered in people with methamphetamine use, particularly given the results in depression (dx.doi.org/10.1017/S003...).

Ryan Smith@rssmith.bsky.social · last yr.

Huge congrats to @clairelavalley.bsky.social on this new paper. www.nature.com/articles/s41.... Results show that methamphetamine users show a specific deficit in model-based planning, in which they fail to simulate plans with large short-term losses (elevated aversive pruning). Brief thread below!

Huge congrats to @clairelavalley.bsky.social on this new paper. www.nature.com/articles/s41.... Results show that methamphetamine users show a specific deficit in model-based planning, in which they fail to simulate plans with large short-term losses (elevated aversive pruning). Brief thread below!

Computational mechanisms underlying multi-step planning deficits in methamphetamine use disorder - Translational Psychiatry

Translational Psychiatry - Computational mechanisms underlying multi-step planning deficits in methamphetamine use disorder

nature.com

Congratulations to co-first author @clairelavalley.bsky.social on validating this new performance-based measure of social emotion regulation ability: emotionandpsychopathology.org/journal/arti... In psychopathology, this may be crucial for maintaining social support. We hope others find it useful!

Very excited to congratulate Ning Li and @clairelavalley.bsky.social on their new paper published in Molecular Psychiatry. "Directed exploration is reduced by an aversive interoceptive state induction in healthy individuals but not in those with affective disorders" (nature.com/articles/s41...) 🧵👇

Directed exploration is reduced by an aversive interoceptive state induction in healthy individuals but not in those with affective disorders - Molecular Psychiatry

Molecular Psychiatry - Directed exploration is reduced by an aversive interoceptive state induction in healthy individuals but not in those with affective disorders

nature.com

Out today in PNAS! We asked how Bayesian inference is implemented in macaque prefrontal cortex www.pnas.org/doi/10.1073/...

Bayesian inference by visuomotor neurons in the prefrontal cortex | PNAS

Perceptual judgments of the environment emerge from the concerted activity of neural populations in decision-making areas downstream of the sensory...

pnas.org

Reinforcement Learning and Active Inference are two frameworks used in computational psychiatry, but these are rarely directly compared empirically. In this new article, we aimed to compare these in a more systematic manner by fitting each to multiple datasets: papers.ssrn.com/sol3/papers....

I'm excited to attend the #ECNP Workshop on Applied Neuroscience and present our findings on markers of abnormal gastrointestinal interoception predicting relapse in anorexia nervosa. Catch Poster P107 on Thursday, March 20, & my oral presentation on Friday, March 21, at 9:10 AM

Congrats to Marishka Mehta on her new chapter! She did a great job summarizing the current state of the field and important future directions. link.springer.com/chapter/10.1... "Computational Approaches for Uncovering Interoceptive Mechanisms in Psychiatric Disorders and Their Biological Basis"

Computational Approaches for Uncovering Interoceptive Mechanisms in Psychiatric Disorders and Their Biological Basis

Interoception, the process of detecting, perceiving, and interpreting signals from within the body, is essential for physiological regulation and adaptive behavior. A growing body of research undersco...

link.springer.com

Excited to congratulate Marishka Mehta on her new preprint (www.medrxiv.org/content/10.1...) combining modeling, machine learning, and longitudinal clinical data. "Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders"

Computational Mechanisms of Approach-Avoidance Conflict Predictively Differentiate Between Affective and Substance Use Disorders

Psychiatric disorders are highly heterogeneous and often co-morbid, posing specific challenges for effective treatment. Recently, computational modeling has emerged as a promising approach for charact...

medrxiv.org

@rssmith.bsky.social and I are working on a symposium proposal on interoceptive and embodied computational psychiatry for this - do let us know if you would like to join as we have open slots. Focus is on quantification and intervention.

Quentin Huys@docqhuys.bsky.social · 2y ago

Poster submissions for the Computational Psychiatry Conference 2025 in Tübingen are now open. Deadline is 7th February. Symposium submissions are open until 15th January. www.cpconf.org. Please RB.

Poster submissions for the Computational Psychiatry Conference 2025 in Tübingen are now open. Deadline is 7th February. Symposium submissions are open until 15th January. www.cpconf.org. Please RB.

Computational Psychiatry Conference

Tübingen, Germany (July 14-16, 2025)

cpconf.org

I could not find a body representation starter pack so I made one! Please message if you want to join. I know I missed excellent scientists, philosophers and clinicians out there go.bsky.app/EAmckAo

Human cortical pyramidal neurons are larger, with more elaborate branching, and distinct nonlinear biophysical properties compared to rat cortical pyramidal neurons. Are they more functionally complex? Could that boost the human brain’s computational power? and is that what makes us human? (1/11)

Just switching over to Bluesky now. Looking forward to good discussions and finding out about new papers again!