Jon Roiser

@jonroiser.bsky.social

Prof of Neuroscience and Mental Health UCL_ICN | Israel&UK politics | Travel adventures | Good food | Trees,wood & fires | Black cat

🚨Our new reviewed preprint is out at eLife! 🎉 Using bi-daily gamified smartphone 📱 tracking, we ask: • Does depressive mood precede under-confidence, or vice versa? • How does depression affect the integration of local confidence into global confidence over time? elifesciences.org/reviewed-pre...

Dense repeated sampling reveals impaired hierarchical integration of metacognitive confidence that scales with depression

elifesciences.org

A key challenge for computational psychiatry is to distinguish state from trait markers and go beyond cross-sectional studies. Here we show that as paranoia waxes and wanes in patients with schizophrenia, so too do volatility priors

Biological Psychiatry@biologicalpsych.bsky.social · last wk.

Individuals with schizophrenia spectrum disorders expect greater volatility in the world, and this cognitive bias is linked to paranoia and delusion severity over time.

I've long suspected this based on our own data - most variation in unselected samples is driven by low symptom scores, and it seems that most covariation is too. Seem important, especially re implications for the "p-factor". We need to confirm correlations from unselected samples in clinical ones

Ashley Watts@ashleylwatts.bsky.social · 4w ago

Excited to share a paper recently accepted at Nature Mental Health! 😄 For decades, we've assumed that covariance among psychopathology informs comorbidity. What if we’ve been wrong?

Andy Burnham is probably going to raise tax by at least £4.7bn, and maybe much more. Here's my list of 37 ways he might do it: every potential tax rise, how much it would raise, and what the downside would be. There's always a downside. Thread:

A chart showing every UK tax. By far the biggest ones are:
- Income tax
- National insurance
- VAT
- Corporation tax

PSA for trainees cold emailing with interest in joining a lab: Be careful about your use of LLMs in writing these emails!! It is now *extremely* common to get emails with a bizarrely-detailed, clearly-LLM take on a paper finding or with specific phrases pulled from the lab website. Don’t do this!

This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!

Eiko Fried@eikofried.bsky.social · 7mo ago

Would love to hear expert views on this paper. It appears to show that the operationalization of brain activity the field has relied on for 3 decades—the BOLD response—is not actually a sensible measure of brain activity. www.nature.com/articles/s41...