In septic shock–associated #AKI, most uremic toxins accumulate—especially in severe AKI—and dialysis lowers several toxin levels. However, toxin trajectories were not associated with 28-day mortality or organ support–free time. #Nephrology #AKI #Sepsis 🔗 journals.lww.com/kidney360/pd...

Pleased to join the Scientific Committee of the XXII Latin American Congress of Nephrology and Hypertension – SLANH 2027, in Panama 🇵🇦, August 25–28, 2027. A privilege to contribute alongside colleagues from across Latin America to an outstanding scientific program. #SLANH2027 #Nephrology

We’re delighted to bring the ISN Primer Course in Renal Pathology to Uruguay, welcoming 73 participants from across Latin America! 🌎 Thanks to our faculty, Hospital de Clínicas & Otsuka for their support.

🤖 Generative AI holds promise in kidney care—but also risks: bias, hallucinations, automation bias, inequitable access & environmental costs. Safe implementation requires recognizing how these risks interact and may affect patient safety and equity. #AI doi.org/10.1093/ckj/...

Potential risks of generative artificial intelligence in kidney care

Abstract. Generative artificial intelligence (GenAI), particularly large language models, is rapidly emerging as a transformative tool in medicine, includi

doi.org

💊 Tosufloxacin & pediatric AKI: a multicenter study found no significant ⬆️ in AKI when the drug was newly initiated. Urinary 💊 crystals were common but did not predict AKI or progression. GI symptoms were strongly associated with AKI. #PedsNephrology link.springer.com/article/10.1...

Acute kidney injury and urinary drug crystals in children treated with tosufloxacin: a multicenter retrospective study - Pediatric Nephrology

Background Tosufloxacin (TFLX), a fluoroquinolone, is widely used in Japanese children with macrolide-resistant Mycoplasma pneumoniae infection. Acute kidney injury (AKI) associated with TFLX has…

link.springer.com

A telehealth-delivered, individualized low-carb nutrition program was associated with a 36% lower risk of new-onset #CKD over 5 years and 62% lower risk of CKD stage ≥4 without increased kidney stones, acidosis, DKA, or gout. #Nephrology #Diabetes 🔗 doi.org/10.1111/dom....

Effectiveness of Telehealth Low‐Carbohydrate Intervention in Preventing Chronic Kidney Disease: A Real‐World, Retrospective, Matched Cohort Study

Background Lifestyle interventions targeting metabolic health may influence chronic kidney disease (CKD) risk, particularly among adults with type 2 diabetes and obesity. We evaluated real-world…

doi.org

Pleased to share our new 📑 consensus statement from ADQI XXXV on accelerating evidence-based practices in acute kidney injury. We provide a roadmap to close evidence-to-care gaps through implementation science, equity, and context-adapted solutions. 🔗 doi.org/10.2215/CJN.... #AKI #ADQI

Accelerating Evidence-Based Practices in Acute... : Clinical Journal of the American Society of Nephrology

Scientific evidence regarding AKI and acute kidney care has advanced in recent years. However, a knowledge gap remains on the implementation of these...

doi.org

Does HCO₃ really not work in #AKI, or are we comparing different strategies? @nephjc.bsky.social A hypertonic HCO₃ bolus differs physiologically from continuous HCO₃-based balanced crystalloids. How HCO₃ is given may matter as much as whether it is used. www.cureus.com/articles/168...

Bicarbonate-Based Solution for the Management of Established Acute Kidney Injury: A Pilot Open-Label Observation Study

Background Administration of intravenous (IV) solutions constitutes a key component of acute kidney injury (AKI) management. However, the optimal IV fluid solution in the setting of AKI remains uncer...

cureus.com

🤖 can identify 🛌 at ⬆️AKI risk before sCr⬆️ but prediction alone doesn’t prevent AKI. A commentary highlights that AI-triggered early nephrology consultation failed to improve kidney outcomes, underscoring the gap between prediction & prevention. 🔗 doi:10.1001/jamanetworkopen.2026.22565

🧒🏼 on CKRT remain at ⬆️risk after critical illness. In a 🇯🇵 PICU registry, 54.7% had MAKE at ICU discharge: ☠️ 18%, dialysis dependence 13%, or persistent 🫘 dysfunction 23.7%. High vasoactive support, hyperK, 🫘 disease & sepsis predicted MAKE. link.springer.com/article/10.1...

Major adverse kidney events at pediatric intensive care unit discharge in a nationwide Japanese pediatric continuous kidney replacement therapy registry - Pediatric Nephrology

Background Major adverse kidney events (MAKE)—a composite of death, new dialysis dependence, and persistent kidney dysfunction—are key outcomes in pediatric patients receiving continuous kidney…

link.springer.com

Ready for day 2 of #AndesCRRT 🇨🇱 2026 #Run4Kidneys 🫘 🏃🏻‍♂️ 🌧️ #850Challenge

#AndesCRRT2026 once again demonstrated the power of collaboration. Inspiring discussions, cutting-edge science, and meaningful exchanges among colleagues dedicated to improving outcomes for patients with AKI and critical illness. Proud to be part of this growing Latin American community. 🌎🤝 #AKI

Children on CKRT with preserved urine output may benefit from an early liberation trial. In the WE-ROCK study, a day-5 liberation trial was associated with better outcomes (win ratio 2.14), mainly through more ICU- and hospital-free days. 🔗 journals.lww.com/cjasn/pdf/10...

Running 🏃🏻‍♂️ around the world 🗺️ and raising awareness of #KidneyDisease 🫘 #Run4Kidneys #850Challenge 🎗️ #SantiagoDeChile 🇨🇱

Urea may be a cost-effective alternative to tolvaptan for 🏥 SIADH patients. In a retrospective 📑 (n=537) both achieved similar correction of HypoNa (>130 mmol/L) while tolvaptan acted faster but caused more overcorrection & was substantially more 💵 🔗https://doi.org/10.1093/ndt/gfag165

Urea vs. tolvaptan for hospitalized patients with SIADH

AbstractRationale. Hyponatremia is the most common electrolyte disorder found in hospitalized patients and is associated with an increased mortality. Urea

doi.org

A machine learning–guided strategy successfully identified 🏥 patients at ⬆️risk for #AKI, but triggering early nephrology consultation didn’t improve 🫘 function, ⬇️readmissions, or ⬇️mortality better prediction does not guarantee better outcomes. 🔗 jamanetwork.com/journals/jam...

Early Nephrology Consult and Acute Kidney Injury in Hospitalized Patients

This randomized clinical trial assesses whether a structured early nephrology consultation triggered by a machine-learning acute kidney injury (AKI) risk score in patients at high risk for AKI improve...

jamanetwork.com

¡Nos vemos en #ANDESCRRT2026! Del 30 de julio al 1 de agosto en Santiago de Chile, compartiendo los últimos avances en #AKI, #CRRT, #POCUS y soporte extracorpóreo junto a destacados expertos de Latinoamérica 🇦🇷 🇧🇴 🇨🇱 🇨🇴 🇪🇨 🇲🇽 🇺🇾. ¡Los esperamos! 🇨🇱🩺🩻 #Nephrology

C5a/C5aR1 may drive the AKI-to-CKD transition. In mice, tubular—not myeloid—C5aR1 promoted inflammation, oxidative stress, apoptosis and fibrosis. C5aR1 deletion or PMX53 enhanced autophagy and mitochondrial function: a therapeutic target. #AKI #CKD 🔗 doi.org/10.1093/ndt/...

C5a/C5aR1 mediates AKI-CKD transition by enhancing autophagy

AbstractBackground. Excessive production of complement C5a detected in acute kidney injury (AKI) and during the development of chronic kidney disease (CKD)

doi.org

Kidney care is no longer just about kidney disease, it’s about #CKM health. There is a evolving role of nephrologists in early screening, prevention, & multidisciplinary care for #CKM syndrome. Breaking silos is essential to improve outcomes. journals.lww.com/cjasn/pdf/10...

Nephrology in the Paradigm of... : Clinical Journal of the American Society of Nephrology

The “Saving Kidneys, Hearts, and Lives” workshop in March 2025, hosted by the American Society of Nephrology, brought together diverse stakeholders...

journals.lww.com

New #NDT study: #Semaglutide did not significantly change measured GFR despite small increases in creatinine and β-trace protein. Combined creatinine+cystatin C eGFR more accurately reflected measured GFR than either marker alone. #Nephrology #CKD 🔗

Effect of Semaglutide on Measured vs Estimated Glomerular Filtration Rate

AbstractBackground and Hypothesis. Semaglutide is a glucagon-like peptide-1 receptor agonist widely used for its glucose-lowering effects in people with ty

doi.org

✍️ ¿Quieres convertir tu investigación en un artículo científico? El curso online «¿Cómo escribir un artículo científico?» te llevará de la hoja en blanco a la revista. 📅 Inicio: 13 de agosto de 2026 🔗 comoescribir.slanh.net #InstitutoSLANH #SLANH #PublicaciónCientífica

¿Cómo escribir un artículo científico? De la hoja en blanco a la revista - SLANH

Fechas: Del 13 de agosto al 2 de septiembre 2026 Objetivo general Aplicar los principios de la escritura académica para transformar las observaciones de la práctica clínica en conocimiento científico ...

comoescribir.slanh.net

Does impaired kidney tubular secretion predict AKI during AHF 💔? In a recent 📑 a secretion score based on 11 endogenous tubular secretion markers measured years before hospitalization was not associated with AKI risk during subsequent #AHF admissions. 🔗 journals.lww.com/kidney360/pd...

Association of Markers of Kidney Tubular... : Kidney360

Background:Acute heart failure (heart failure) is a common cause of acute kidney injury (AKI) in hospitalized patients, yet it remains unclear why...

journals.lww.com

¡Buena carrera esta mañana con el jersey del equipo de atletismo de la U de Chicago! 🏃‍♂️💨 Gracias a mi amigo Jay Koyner por la cortesía. ¡A seguir sumando kilómetros! #ChicagoMaroons #Running

Severe pregnancy-associated AKI is rising. In 4.09M US pregnancies, severe PrAKI nearly tripled by the COVID-19 era. Maternal mortality increased, while dialysis use remained stable. Key risks: hypertension, obesity, diabetes, CKD, age & COVID-19. 🔗 doi.org/10.1093/ndt/...

How is dialysis-requiring AKI managed across Latin America? The #LATAMAKID registry will provide the first multinational characterization of epidemiology, RRT practices, and outcomes across 10 countries—helping shape future AKI care and policy. #AKI 🔗 doi.org/10.1136/bmjo...

In 672 US adults with diabetes and CKD, serum uric acid was not linked to all-cause mortality. However, SUA >9 mg/dL was associated with higher cancer mortality, combined CVD/cancer mortality, and CVD mortality in those without baseline CVD. 🔗 doi.org/10.1038/s415...

The retraction of the ADVOCATE trial marks a pivotal moment for ANCA-associated vasculitis. Scientific integrity is non-negotiable. Yet, patients should not lose access to effective therapies because of research misconduct. Regulators must balance evidence, safety, & patient care

#JustDoItSunday 🏃🏻‍♂️ #Run4Kidneys 🫘 #850Challenge 🎗️and raise awareness of #KidneyDisease

Should fish oil be recommended to all patients on hemodialysis? The PISCES trial reported a 43% reduction in cardiovascular events with EPA/DHA, but uncertainties remain regarding atrial fibrillation and event rates. Shared decision-making is essential. 🔗 journals.lww.com/kidney360/pd...

High altitude–associated kidney injury is an evolving field. A new 📑 highlights key mechanisms—including hypoxia signaling, oxidative stress, mitochondrial dysfunction, and the gut–kidney axis—and explores emerging therapies beyond acetazolamide. 🔗 doi.org/10.1016/j.xk...