OK, not a "tremendous breakthrough", but it is nice to have it completed - the first project in the group, started after moving to @hhu.de years ago, as a part of CRC 1208 (1st C is for "collaborative"). Thanks to all the co-authors for the joint effort and resilence ✊🤓 www.jbc.org/article/S002...

Conformational dynamics of the membrane-anchored foldase LipH from Pseudomonas aeruginosa governs recognition and release of its client lipase

The lipase LipA from Pseudomonas aeruginosa is an extracellular enzyme that plays an important role in bacterial infections. Prior to its export via the type II secretion system, LipA requires the cog...

jbc.org

Excited to share our latest publication!🚀🙏🏼🤩 We present ATPLyzer, an advanced ratiometric biosensor that is a clear step forward in sensor-related ATP-research, opening new perspectives for future applications. 📄 advanced.onlinelibrary.wiley.com/doi/10.1002/...

ATPLyzer—An Advanced Ratiometric Multi‐Color Biosensor for Long‐Term Monitoring of ATP Dynamics

ATPLyzer is a family of genetically encoded ratiometric biosensors developed for real-time monitoring of intracellular ATP dynamics in living cells. Using a Matryoshka design with single-wavelength e....

advanced.onlinelibrary.wiley.com

#Plastids appear to make use of the same protein as mitochondria to resolve #ribosome stalling by proline motifs. A fun project with great colleagues from @helsinki.fi Mitochondria and plastids really are best buddies that share everything.

Neue Therapieansätze gegen aggressiven Brustkrebs Bundesforschungsministerium fördert KI-Forschungsprojekt TriNova Das Bundesministerium für Forschung, Technologie und Raumfahrt (BMFTR) fördert das Projekt „TriNova“ an der Heinrich-Hein... weiterlesen

Der Biologe Dr. Florian Altegoer vom Institut für Mikrobiologie der Heinrich-Heine-Universität Düsseldorf (HHU) erhält einen mit 210.000 Euro dotierten „Exploration Grant“ der Boehringer Ingelheim Stiftung (BIS).

History in the making! 🎓 Huge congratulations to Nora Zöllner, who successfully defended her PhD - earning top honors! Nora is the very first graduate of our MibiNext cohort. We couldn’t be prouder! A massive achievement for her and a major milestone for the entire network. #MibiNet #MibiNext

Standing ovations for an incredible Maya Schuldiner, who just received the Otto Warburg Metal at the #MosbacherKolloqium of the @gbmev.bsky.social and delivered the most impressive, passionate speeches one can imagine... beautiful oration by Christian Ungermann and many tears in the lecture hall 🧪💕

This year‘s Lynen Lecture was held by Bruno Antonny (Valbonne, France). Robert Ernst gave the laudatio for Bruno‘s scientific achievements.

Breakthrough article 😊 Joint effort of teams Zarnack & König & Feldbrügge clarifies how multiple RNA-binding domains cooperate to identify functional important binding sites in vivo doi.org/10.1093/nar/... @zarnack-group.bsky.social @könig-lab.bsky.social @mibinet.bsky.social #EMBOrnaLocalization

Dissecting the RNA-binding capacity of the multi-RRM protein Rrm4 essential for endosomal mRNA transport

Abstract. RNA-binding proteins (RBPs) utilize multiple RNA-binding domains (RBDs) to engage with extensive messenger RNA (mRNA) networks. Understanding the

doi.org

First conference of the newly founded interfaculty Center of Membrane Research at HHU. Two days of exciting talks about all areas of membrane research. Thanks to all speakers and participants for a great time. For sure worth to be repeated!

@spp2330.bsky.social

Peter Fineran@peterfineran.bsky.social · 5mo ago

New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments.

Thanks for highlighting our work done at @hhu.de @chemiehhu.bsky.social published in @angewandtechemie.bsky.social , Aubrey @aubreyzerkle.bsky.social! Rare earth elements rock! doi.org/10.1002/anie...

Influence of Rare Earth Elements on Prebiotic Reaction Networks Resembling the Biologically Relevant Krebs Cycle

Rare earth elements can act as mediators in a prebiotic reaction network, producing various intermediates of the citric acid cycle starting from glyoxylate and pyruvate. The ionic radius and the resu...

doi.org

Aubrey Zerkle@aubreyzerkle.bsky.social · 5mo ago

New Astrobiology Revealed! @daumannl.bsky.social and @joguti.bsky.social describe how rare earth elements could play an important role in prebiotic chemistry. #SciComm #SciNews www.saganet.org/articles/ast...

AP4A functions as a regulatory switch of protein acetylation, connecting stress signaling to central metabolism. @synmikro.bsky.social @unimarburg.bsky.social @mpimicrobiomarburg.bsky.social Enjoy the reading: 
www.nature.com/articles/s41...

Lasse presents our CRC1535 MibiNet project at the first RNA confluence meeting at the EMBL. @rhinelandrna.bsky.social @mibinet.bsky.social

‪ Please RT: Looking forward to our International Symposium on "Microbial Networking - from organelles to cross-kingdom communities". Highlight of our first funding period of our Collaborative Researc Center @mibinet.bsky.social, @dfg.de www.sfb1535.hhu.de/mibinet @hhu.de , @fz-juelich.de

Super happy to share that our Chemical Science article ‘Structural control of dynamic covalent cages: kinetic vs. thermodynamic assembly and PFAS removal from water’ (pubs.rsc.org/doi/D5SC02247A) has been selected for the 2025 most popular supramolecular articles collection 🎉

Happy to announce that our review article on vesicle-coupled mRNA trafficking is now availalbe @mibinet.bsky.social #EMBOrnaLocalization link.springer.com/article/10.1...

I feel very grateful that our recent publication on rapid biosensor creation has been announced by HHU (Heinrich Heine University Düsseldorf). 🍀🙏🏼🤩🧪🦠🧫🔬 www.hhu.de/news-einzela...

Strukturanalyse: Veröffentlichung in ACS Sensors

Um Stoffwechselprozesse zu verstehen, ist es wichtig, einzelne wichtige Elemente in lebenden Organismen nachweisen zu können. Forschenden der Heinrich-Heine-Universität Düsseldorf (HHU) entwickelten n...

hhu.de

✨ I am thrilled to share ✨ that our paper on computational biosensor design has just been published! Huge thanks to all co-authors and collaborators for the great teamwork and dedication throughout this journey! 🙌 📄 Read the paper here: pubs.acs.org/doi/10.1021/...

A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design

Genetically encoded biosensors enable the monitoring of metabolite dynamics in living organisms. We present CoBiSe, a computational biosensor design approach using Constraint Network Analysis to ident...

pubs.acs.org

We Are very happy that our Paper was published. Thank to everyone involved pubs.acs.org/doi/10.1021/... @mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social

🔬 Job Alert! 🚨 Goethe University Frankfurt is hiring a Head of our new Imaging Facility at Campus Riedberg! Lead and support a vibrant imaging community, working with cutting-edge microscopes, e.g. a new Zeiss LSM 980, a Z1 Light Sheet, and a new Leica Stellaris. gerbi-gmb.de/resources/ca...

Yvonne Stahl@yvonnestahl.bsky.social · 8mo ago

🚨JOB ALERT! We’re hiring a Head of the new Imaging Facility at Goethe University Frankfurt. You’ll support researchers across disciplines, train users, and help enable cutting-edge science with high-end microscopy platforms. tinygu.de/TknxZ If facility-building + imaging is your thing, please apply!

Werde Teil des Teams @hhu.de: #Stellenangebot, scheinbar unbefristet. Grüße an #ichbinHanna & #ichbinReyhan

Abteilungsleitung (m/w/d) Forschungsmanagement und Transfer - Heinrich-Heine-Universität Düsseldorf

Heinrich-Heine-Universität Düsseldorf bietet Stelle als Abteilungsleitung (m/w/d) Forschungsmanagement und Transfer in Düsseldorf - jetzt bewerben!

jobs.zeit.de

Very happy to See This Published!!!! Thanks for the collaboration link.springer.com/article/10.1...

Vesicle-coupled mRNA transport and translation govern intracellular organelle networking - EMBO Reports

Eukaryotic cells are highly compartmentalized, enabling sophisticated division of labour. For example, genetic information is stored in the nucleus while energy is produced in mitochondria. Despite th...

link.springer.com

Very happy to See This Published!!!! Thanks for the collaboration link.springer.com/article/10.1...

Vesicle-coupled mRNA transport and translation govern intracellular organelle networking - EMBO Reports

Eukaryotic cells are highly compartmentalized, enabling sophisticated division of labour. For example, genetic information is stored in the nucleus while energy is produced in mitochondria. Despite th...

link.springer.com

Finally out – It is all about cholesterol Thanks to all for this excellent collaboration

📢Postdoc position available!🧪🧫🧬 Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions. Full details & application: karriere.hhu.de//index.php?a.... Please help us get the word out!

Postdoc (m/f/d) in Endosymbiosis Research

karriere.hhu.de

Die DFG fördert Projekte für ressourceneffizientere Großgerätenutzung in der Forschung mit insgesamt ca. 5,5 Mio €. Außerdem werden zusammen mit der GWK bis Ende 2025 Anträge unter dem üblichen Schwellenwert möglich, die eine längere Nutzung vorhandener Geräte erlauben. Details: sohub.io/r4km

DFG fördert Projekte für ressourceneffizientere Großgerätenutzung in der Forschung

sohub.io

✨X-ray crystallography reveals surprising twist in how proteins enter the unique photosynthetic organelles of Paulinella. The chromatophore targeting peptide (crTP) folds into a 3D structure, hinting that folded proteins cross peptidoglycan and inner membrane. (1/2) academic.oup.com/plphys/artic...

New publication in J Mol Biol New insights in to the function of the CLD and the entire hemolysin secretion machinery. Thanks to Holger Gohlke’s lab and CSS for the wonderful collaboration. Congrats to Sakshi and Cigdem!

🚨Our paper is out! 🥳 Hijacking a bacterial ABC transporter for efficient genetic code expansion. Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social www.nature.com/articles/s41... it all started years ago with a failed experiment 🧵👇 1/9

Hijacking a bacterial ABC transporter for genetic code expansion - Nature

Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...

nature.com