📰 Nice, @vbio.bsky.social (the German Life Sciences association) posts about our work with #bacteriophages in #Plant #Protection. 🧪 #PlantScience #SciCom www.vbio.de/aktuelles/de... @fz-juelich.de @frunzkelab.bsky.social @guidogrossmann.bsky.social

Viren als Pflanzenschützer: Das Potenzial von Bakteriophagen

Bakterien können nicht nur Menschen und Tiere krank machen, sondern auch Pflanzen. Weltweit verursachen bakterielle Pflanzenkrankheiten erhebliche Ernteverluste. Für die Landwirtschaft ist das ein wac...

vbio.de

Congratulations Aude and team! @spp2330.bsky.social

Aude Bernheim@audeber.bsky.social · 2w ago

Out @cp-cellhostmicrobe.bsky.social, natural products meet bacterial immunity! We used genomics to identify lanthivirins: a family of >2,000 lanthipeptide BGCs that protect Actinobacteria against phages. Led by @hshomar.bsky.social & @mariegllm.bsky.social www.sciencedirect.com/science/arti...

2/10 The biological roles of most bacterial natural products remain unknown. A few were shown to provide antiphage phenotypes, as early as 1945 by Doris Jones and more recently by the @themaxwelllab.bsky.social and @frunzkelab.bsky.social labs. Ex: www.nature.com/articles/s41...

Latest science in press 🗞️: Biosustainable plant protection using #viruses (bacteriophages) 🧪 🦠 #PlantScience #botany #PlantMicrobeInteractions @fz-juelich.de @ceplas.bsky.social @mibinet.bsky.social www.fz-juelich.de/en/news/arch...

Borjana Arsova@borjana-a.bsky.social · last mo.

‪ #Bacteriophages help sustainable plant protection ✅#Phages restore 🌱 growth during 🦠 infection. ✅🧬 shows ⬇️🌱immunity & ⬇️bacterial virulence. #Biocontroll #PlantSci 🧪 #PMI @frunzkelab.bsky.social @guidogrossmann.bsky.social @mibinet.bsky.social @fz-juelich.de www.cell.com/cell-reports...

www.hhu.de/news-einzela...

Mikrobiologie: Veröffentlichung in Cell Reports

Forschende der Heinrich-Heine-Universität Düsseldorf (HHU) und des Forschungszentrums Jülich (FZJ) untersuchten, wie natürliche Viren, die gezielt Bakterien befallen („Bakteriophagen“), Pflanzen vor b...

hhu.de

Our paper out in Science today: The Metis defense system senses molecular byproducts released when a phage degrades the bacterial genome, and then prevents replication of the phage in the infected cell Congratulations @ostermanilya.bsky.social and co-authors!

Bacteria sense virus-induced genome degradation via methylated mononucleotides

Phages often degrade the genome of their bacterial host to individual nucleotides. Here we describe Metis, a bacterial defense system that directly senses phage-mediated host genome degradation. Metis...

science.org

Osterman Ilya@ostermanilya.bsky.social · 4w ago

Excited to share that our Metis story is now published in Science! 🎉 Bacteria can sense phage-induced degradation of their genome and activate immunity. Many thanks to everyone who contributed to this work. 📄 www.science.org/doi/10.1126/... More details in my earlier thread 🧵⬇️

@sebastianbeier.bsky.social has fixed some minor issues in our read trimmer Trimmomatic for R0.41 since the latest release just a few months ago academic.oup.com/bioinformati.... github.com/usadellab/Tr.... Please note, that the website trimmomatic.com is not ours and send you to commercials.

Trimmomatic: a decade of feature-rich, high-performance NGS read preprocessing

AbstractMotivation. Trimmomatic is a widely adopted tool for preprocessing high-throughput sequencing data, particularly from Illumina platforms. Since its

academic.oup.com

Happy to share our latest finding on ComFB, a new #cdiGMP receptor in bacteria Team effort w/ @freecyano.bsky.social at @sfb1381.bsky.social ComFB regulates type IV pilus-dependent functions via sequestering TFs (CRP1/2) @hhu.de @biologyunifreiburg.bsky.social www.sciencedirect.com/science/arti...

🚨 Registration for VEGA26 is 👏 officially open 👏 🚨 The 5th edition of our Viral EcoGenomics and Applications symposium will be held November 18-19, 2026, on the UC Berkeley campus 🧬 🦠 🔬 🧫 Event website ➡️ jgi.doe.gov/work-with-us... Registration link ➡️ cvent.me/e0RnA0

Looking forward to Viruses of Microbes 2026 in Prague!

How can we harness the vast functional diversity of microbes on our planet? Join us at EMBL Heidelberg from 8–10 December 2026 to hear about ongoing efforts to decode gene function and organisation in human gut microbes, and to present your own research. www.embl.org/about/info/c...

What is the impact of phage biocontrol on plant immune responses and bacterial virulence? Very happy that this is out @cp-cellreports.bsky.social! @mibinet.bsky.social, @dfg.de, @fz-juelich.de, @hhu.de, @spp2330.bsky.social

Borjana Arsova@borjana-a.bsky.social · last mo.

‪ #Bacteriophages help sustainable plant protection ✅#Phages restore 🌱 growth during 🦠 infection. ✅🧬 shows ⬇️🌱immunity & ⬇️bacterial virulence. #Biocontroll #PlantSci 🧪 #PMI @frunzkelab.bsky.social @guidogrossmann.bsky.social @mibinet.bsky.social @fz-juelich.de www.cell.com/cell-reports...

Open postdoc position in my lab on HGT and interbacterial competition. We seek candidates with a PhD in microbiology (or related fields)+ strong 1st-author publications. Curious, highly motivated, and dedicated team players ready to contribute fully are encouraged to apply. Details: tiny.cc/cz01101

Open Positions

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tiny.cc

Congratulations @athanasios-ppdpls.bsky.social and @mibinet.bsky.social!

Papadopoulos @ HHU@athanasios-ppdpls.bsky.social · last mo.

Excited to share our latest publication!🚀🙏🏼🤩 We present ATPLyzer, an advanced ratiometric biosensor that is a clear step forward in sensor-related ATP-research, opening new perspectives for future applications. 📄 advanced.onlinelibrary.wiley.com/doi/10.1002/...

Beyond AMGs: Phage-encoded transcription and sigma factors as understudied virocell reprogramming tools #phage #phagesky Trends in Microbiology www.cell.com/trends/micro...

Beyond AMGs: Phage-encoded transcription and sigma factors as understudied virocell reprogramming tools

Phages, the most abundant biological entities on Earth, infect bacteria and reprogram them into ‘virocells’ with altered physiology and ecology. While metagenomic studies have largely inferred reprogr...

cell.com

📣 We are hiring! In the collaborative research center 'Plant Ecological Genetics' @teamthomma.bsky.social searches a PhD candidate to study the role of plant-associated microbiota in plant density responses and inter-plant competition. See project A07: sl1nk.com/b7z0doc Deadline July 10!

Dr. Michael Sauer, FEMS Board Member and ÖGMBT President, invites you to join him this year in Vienna as collaboration takes centre stage at the FEMS Regional COLLAB. Discover how collaboration can transform ideas into impact. ⏰ 23 June EB Deadline: buff.ly/pg2yXvN

As promised: We have an open 2-year postdoc position in my lab at HHU Düsseldorf, starting September 2026. Come join us and help pioneering structural biology of fungal GPCRs! More about the lab: altegoerlab.de Apply here: karriere.hhu.de/index.php?ac... Please share with interested candidates!

Postdoc (m/f/d) structural biology of fungal G-Protein coupled receptors

karriere.hhu.de

Altegoerlab@faltegoer.bsky.social · 4mo ago

We just received funding for a 2yr postdoc position on cryoEM of fungal gpcrs. Official call will open soon. Contact me if you‘re interested!

NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back Preview of work IDing aRES, bacterial proteins that deplete cellular NAD+, generating products that cannot be utilized by phage NAD+ regeneration pathways www.cell.com/cell-host-mi...

NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back

In this issue of Cell Host & Microbe, Osterman et al. discover aRES, a new family of bacterial immune proteins that deplete cellular NAD+, generating cleavage products that cannot be utilized by canon...

cell.com

Our review on structural mechanisms of #CO2 fixation machinery by #cyanobacteria @theplantjournal.bsky.social is out🎉🎉 When #CO2 is limiting, #cyano concentrate it. Discover how they thrive? @hhu.de @ceplas.bsky.social @mibinet.bsky.social @sfb1381.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

Functional and structural insights into cyanobacterial CO2 concentrating mechanisms: from compartmentalization to regulation

Life on Earth depends on photosynthetic CO2 fixation via the Calvin–Benson–Bassham cycle to form organic carbon. This process evolved first in cyanobacteria and was later conveyed to eukaryotes, givi...

onlinelibrary.wiley.com

#Biofilm matrices containing filamentous phages help #Pseudomonas aeruginosa tolerate antibiotics. @abultarafder.bsky.social @tbharat-lab.bsky.social &co show that #nanobody disruption of #phage Pf4 #LiquidCrystalline droplets restores #antibiotic susceptibility @plosbiology.org 🧪 plos.io/4xkd6Mw

Now out in @pnas.org 🥳 "DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity" --> bad timing can kill you, even as a virus. www.pnas.org/doi/10.1073/... @spp2330.bsky.social, @mibinet.bsky.social, @dfg.de

Julia Frunzke@frunzkelab.bsky.social · 7mo ago

Happy to share our recent preprint: "DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity" www.biorxiv.org/content/10.6... @spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social

Please RT: Registration is ongoing for our International Symposium "Microbial Networking - from organelles to cross-kingdom communities" organized as highlight of the first funding period of CRC 1535 @mibinet.bsky.social www.sfb1535.hhu.de/internationa... @dfg.de, @hhu.de, @fz-juelich.de

Registration opened for our International Symposium of SPP 2330! This is going to be phage-tastic meeting in Berlin! Highlight of the second funding period! @spp2330.bsky.social, @dfg.de

New Concepts in Prokaryotic Virus-Host Interaction@spp2330.bsky.social · 3mo ago

📢 Registration for our International Symposium on “New Concepts in Prokaryotic Virus-Host Interactions” is now open! 🗓️ 5–7 October 2026 📍 Harnack House, Berlin, Germany ➡️ Information and registration: spp2330.de/symposium-20...

Happy to share our latest pre-print on the Druantia defense system. We find that Type III Druantia uses a cooperative helicase-nuclease mechanism to sense and degrade replication-associated forked DNA structures. www.biorxiv.org/content/10.6... A🧵

Our paper is out! Hiding in plain sight among Cas12a nucleases, Cas12a3 cleaves not its RNA target but the 3′ ends of tRNA. Huge thanks to all who made this possible, especially the Beisel lab, Biao & Dirk for the structure, & @sebastianglatt.bsky.social for all things tRNA. doi.org/10.1038/s415...

RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity - Nature

Cas12a3 nucleases constitute a distinct clade of type V CRISPR–Cas bacterial immune systems that preferentially cleave the 3′ tails of tRNAs after recognition of target RNA to induce growth arres...

nature.com

Must read: @spp2330.bsky.social

Mart Krupovic@mkrupovic.bsky.social · 3mo ago

With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...

David Attenborough has raised awareness of the natural world and its myriad interconnections on which humans depend go.nature.com/48RTqVz

Happy 100th birthday David Attenborough! Nature salutes you

Nature - The science communicator has raised awareness of the natural world andits myriad interconnections on which humans depend.

go.nature.com

Experienced researchers are less likely to produce ‘disruptive’ science than are those just starting their careers, finds an analysis of scientific papers published by 12.5 million researchers over 60 years go.nature.com/3Pb1lqg

Early-career researchers do more ‘disruptive’ science than veterans

Nature - Analysis of papers from millions of scientists shows that older researchers tend to stick with ideas from their past.

go.nature.com

Exciting times for our lab- recent developments in cryoET tools and workflows now allow us apply these to study microbes in the host context. #teamtomo www.sciencedirect.com/science/arti...

Beyond resolution: Cryo-electron tomography of microbial nanomachines in native host context

Cryo-electron tomography (cryo-ET) has revolutionized visualization of bacterial nanomachines by revealing molecular structures in situ under near-nat…

sciencedirect.com