Congratulations to George, Andras, @lakatoslab.bsky.social and collaborators for the publication of the human motor axis in dish! As a neurologist, it was amazing to see the corticospinal tract in vitro and how it can reveal new strategies for axon regrowth after injury. www.cell.com/cell-reports...

We are excited to share our new pre-print "Mecp2 deficiency impairs microscale cortical network topology and dynamics in a Rett syndrome mouse model" on bioRxiv! www.biorxiv.org/content/10.6...

Hurrah! The bioRxiv preprint introducing MEA-NAP is now linked to the Cell Reports Methods publication! #MEA-NAP

Jeremi spotted this cool paper studying Parkinson's disease in midbrain-striatum organoids that assessed the degree of functional connectivity, between different regions of their assembloid on the microelectrode array, using MEA-NAP! www.nature.com/articles/s42...

Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids - Communications Biology

Generation of a midbrain-striatum assembloid with progerin overexpression as an in vitro model of possessing aging and senescence characteristics for studying Parkinson’s disease.

nature.com

Congrats to Yiwei Gong on posting on arXiv her PhD work featuring our new network dynamics method for MEA data! arxiv.org/abs/2411.04229 #neuroscience

Detecting State Changes in Functional Neuronal Connectivity using Factorial Switching Linear Dynamical Systems

A key question in brain sciences is how to identify time-evolving functional connectivity, such as that obtained from recordings of neuronal activity over time. We wish to explain the observed phenome...

arxiv.org

Our MEA-NAP video abstract appears on the Cell Press YouTube channel with an #elephant-showering!! youtu.be/RJuvSDivApQ?...

3D human brain organoid neuronal network analysis strategies: an exciting collaborative work led by Susanna Mierau - and more to come: www.cell.com/cell-reports...