🚨New preprint from PGC SUI!! @pgcgenetics.bsky.social GWAS meta-analyses of suicidal ideation, attempt, death, and behavior across >50 cohorts identify 77 loci (59 novel), implicate subcortical brain regions, and show suicidality phenotypes are genetically distinct. www.medrxiv.org/content/10.1...

Genome-wide association studies identify 77 loci for suicidality and provide novel biological insights

Suicidality is heritable and a leading cause of global morbidity and mortality, yet its biological etiology remains largely elusive. We conducted multi-ancestry genome-wide association study meta-anal...

medrxiv.org

The PGC Suicide Working Group will provide a symposium at #WCPG2025 🇲🇽 covering our latest multi-ancestry GWAS and CNV meta-analyses, sex-specific meta-analyses, and GxEHR analyses. 🥳 @lcstoshio.bsky.social @andreyshabalin.bsky.social @sarahcolbert.bsky.social @caina89.bsky.social

@sarahcolbert.bsky.social ‘s #SRS25 presentation: Genome-Wide Association Studies of Suicidal Thoughts and Behaviors in the Psychiatric Genomics Consortium So incredible!

US military budget: $850 billion US National Institutes of Health indirect costs: $9 billion That they are so focused on cutting the budget of the latter says everything.

Happy to share the preprint of our GWAS of DSM-defined nicotine dependence! Thanks to all my coauthors for their hard work on this, especially co-first author Dongbing Lai & my fellow PGC SUD analysts for their many helpful suggestions.

medRxivpreprint@medrxivpreprint.bsky.social · 2y ago

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. https://www.medrxiv.org/content/10.1101/2025.01.29.25320962v1

1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in @cellpress.bsky.social. www.cell.com/cell/fulltex... A thread 🧵: