What if part of Huntington's disease wasn't just damage, but a circuit stuck in the wrong pattern? Our new paper, out today in Nature, tests that idea.
Sonja Blumenstock
@sblumenstock.bsky.social
Neuroscientist, spying on circuits in health and disease 🐭🔬
Motor deficits in Huntington's disease mice were rescued by targeted activation of cortical inhibitory neurons. As a winner of the Emerging Neuroscientist Seminar Series, Dr Sonja Blumenstock, UCSD, explains her findings: www.sainsburywellcome.org/qa/targeting... #BrainAwarenessWeek
So excited to present my research at ENSS 2025/2026!
Sainsbury Wellcome Centre@sainsburywellcome.bsky.social · 12mo agoCongratulations to the SWC Emerging Neuroscientists Seminar Series winners! - Dimokratis Karamanlis, University of Geneva - @rafsarnataro.bsky.social & Peter S. Hasenhuetl, @ox.ac.uk - Saurabh Vyas, @columbiauniversity.bsky.social - @sblumenstock.bsky.social, University of California San Diego
Hi Bluesky, past time for an introduction! I’m Sonja, a Neuroscientist at UCSD. I track + tweak cortical circuits in Huntington’s disease using 2P imaging & optogenetics — to see how specific neurons fail, and how to fix them. Always up for talking circuits, neurodegeneration & smart analysis ideas.
