Natale R. Sciolino, PhD

@sciolinolab.bsky.social

Norepinephrine brain circuits regulating feeding, taste, and aversion. Asst Prof UConn| NIDCD R01| NIDDK R00| NARSAD Grant | BRF Seed Grant| Postdoc NIEHS| PHD UGA https://www.sciolinolab.org/ WE ARE HIRING A POSTDOC.

Happy to share that my lab received an NIH R01 award focused on studying how norepinephrine from the locus coeruleus shapes cortical taste coding, using imaging, optogenetics, fiber photometry, & behavior. Excited to explore how neuromodulatory dynamics shape hedonic regulation & decision-making.

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🧪 I might be the only author on Blueksy, so here we go. Serotonin in the caudate while doing uniquely human things (a social game) provides information about movement disorder diagnosis. This work started a long time ago with Ken (when he was at Wake Forest) working with Read at VT. rdcu.be/eDDPf

Caudate serotonin signaling during social exchange distinguishes essential tremor and Parkinson’s disease patients

Nature Communications - Measurements of dopamine, serotonin and norepinephrine in the caudate of conscious humans reveal a neurochemical boundary between patients with essential tremor and...

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Our new preprint: 𝐅𝐞𝐚𝐭𝐮𝐫𝐞-𝐬𝐩𝐞𝐜𝐢𝐟𝐢𝐜 𝐭𝐡𝐫𝐞𝐚𝐭 𝐜𝐨𝐝𝐢𝐧𝐠 𝐢𝐧 𝐥𝐚𝐭𝐞𝐫𝐚𝐥 𝐬𝐞𝐩𝐭𝐮𝐦 𝐠𝐮𝐢𝐝𝐞𝐬 𝐝𝐞𝐟𝐞𝐧𝐬𝐢𝐯𝐞 𝐚𝐜𝐭𝐢𝐨𝐧. We describe how the LS guides defensive responses by forming critical computations built from functionally and molecularly distinct cells and their afferent inputs. www.researchsquare.com/article/rs-6...

Feature-specific threat coding in lateral septum guides defensive action

The ability to rapidly detect and evaluate potential threats is essential for survival and requires the integration of sensory information, with internal state and prior experience. The lateral septum...

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