I am so excited to share with the community my newest pre-printed manuscript w/ my mentor @brainsonmymind.bsky.social investigating striatal astrocytes and neuromodulation in Parkinsonian conditions! www.biorxiv.org/content/10.6...

Striatal cholinergic and dopaminergic driven astrocyte Ca2+ activity is disrupted in Parkinsonian mice

Brain neuromodulatory systems exert powerful effects on local neuronal circuit function and behavior. In addition to classical actions directly on neurons, growing evidence indicates that neuromodulat...

biorxiv.org

New work from our lab done by the amazing @cherishardinger.bsky.social !!!

Cherish Ardinger, PhD@cherishardinger.bsky.social · 2mo ago

You’re at the bar having that first drink of the night 🍻 the excited, energized feeling you may have is the “stimulant response” to alcohol - a risk factor for alcohol use disorder. We researched an understudied cell-type’s role in this response #neuroskyence www.biorxiv.org/cgi/content/...

Thrilled to wrap up the year and my postdoc work in the Nester lab with this publication 🥳! We show that astrocytic CREB regulates astrocyte calcium and D1-MSN activity to drive behavioral response to cocaine. pubmed.ncbi.nlm.nih.gov/41406210/

At #SfN? Check out super talented graduate student Esther's poster on how acute alcohol modulates cell specific in vivo cortical activity. You can also congratulate her on recently defending her Masters thesis!!

Some sparsely-labeled VTA astrocytes for #fluorescenceFriday Green=GCaMP, red=jRGECO

Thrilled to share this work from my postdoc with Tom Carmichael, available online @ Neuron! Long story short: we find even more evidence that all reactive astrocytes are not equal, and we can take advantage of those differences to improve repair after stroke. www.sciencedirect.com/science/arti...

Regionally mapped astrocytic responses to cortical and white matter stroke show differential roles in astrocyte-induced vascular remodeling

Stroke is a major cause of disability. Astrocytes respond to stroke in a gradated manner, but details of that response and its consequences for tissue…

sciencedirect.com

Here's a look at a field of striatal astrocytes expressing GCaMP6f-cyto from the Huda Lab for #FluorescenceFriday !

So glad to see our new paper out as a #GliaPaper #GliaJune2025 !!!!

Shane Liddelow@liddelowsa.bsky.social · last yr.

#GliaPapers #GliaJune2025 RESEARCH Wesley Evans, …, @brainsonmymind.bsky.social @rutgersu.bsky.social Chemogenetic control of striatal astrocytes improves parkinsonian motor deficits in mice onlinelibrary.wiley.com/doi/10.1002/...