Sandra V. Gomez-Gutierrez

@sgomezguti.bsky.social

Postdoctoral researcher @ Purdue Biology - ecsolab.com 🧬👩‍🔬 | Evolutionary history of nascent genes | Adaptation in microbial populations 🦠| Plant Pathologist and Computational biologist. Evolutionary biologist in training 👩‍💻

Happy to finally see this as a preprint in bioRxiv Genetics. We were able to disrupt a target effector gene using CRISPR/Cas9 in Zymoseptoria tritici for the first time. Thanks to our collaborators from @w-u-r.bsky.social who shared and contributed all their knowledge and experience!

bioRxiv Genetics@biorxiv-genetic.bsky.social · 4mo ago

Development of a CRISPR/Cas9-mediated transformation procedure for the wheat pathogen Zymoseptoria tritici https://www.biorxiv.org/content/10.64898/2026.05.27.728285v1

Check the most recent publication from my Ph.D. work published in Molecular Plant-Microbe Interactions Journal! Happy to contribute to understanding the Zymoseptoria infection strategy and see this finally out for the community!

Molecular Plant-Microbe Interactions® (MPMI)@mpmijournal.bsky.social · 7mo ago

To investigate infection phase-specific gene expression in #Zymoseptoria tritici, Sandra V. Gomez-Gutierrez et al. analyzed gene expression during infection of susceptible and resistant wheat cultivars, as well as the nonhost species barley: https://doi.org/10.1094/MPMI-07-25-0090-R

Fig. 10.
Subcellular localization of six Zymoseptoria tritici effectors in Nicotiana benthamiana leaf cells expressed without their putative signal peptides.

👋 Hi #AcademicSky! Together with @smbe-idea.bsky.social I’m organizing a symposium at #SMBE2026 (Copenhagen) 🇩🇰 🌈 Our mission is to 𝗮𝗺𝗽𝗹𝗶𝗳𝘆 𝘂𝗻𝗱𝗲𝗿𝗿𝗲𝗽𝗿𝗲𝘀𝗲𝗻𝘁𝗲𝗱 𝘃𝗼𝗶𝗰𝗲𝘀 𝗶𝗻 𝗺𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗯𝗶𝗼𝗹𝗼𝗴𝘆 & 𝗲𝘃𝗼𝗹𝘂𝘁𝗶𝗼𝗻 📣 Call for abstracts 𝗢𝗣𝗘𝗡 ⏰ Deadline: 𝗙𝗲𝗯 𝟯 ✨ Hope to see you there! 😉 @official-smbe.bsky.social

SMBE IDEA taskforce@smbe-idea.bsky.social · 8mo ago

Join us for the IDEA Symposium at SMBE 2026 (June 28–July 2) in Copenhagen! We celebrate SMBE’s commitment to inclusion, equity, and diversity by addressing systemic inequities in molecular biology and evolution. 💬 Like to participate? Abstract deadline is February 3rd! smbe2026.org/symposia/

New preprint reveals bacteria can't just collect all resistance genes like Pokemon cards. We found mutually exclusive evolutionary pathways to multidrug resistance in E. coli & P. aeruginosa - some resistance mechanisms actively prevent others from coexisting www.biorxiv.org/content/10.1...

Genomic constraints shape the evolution of alternative routes to drug resistance in prokaryotes

Background Variation within the prokaryotic pangenome is not random, and natural selection that favours particular combinations of genes appears to dominate over random drift. What is less clear is wh...

biorxiv.org

Happy to share our latest preprint! We show that two Z. tritici effectors trigger necrosis in Nicotiana, and that ROS modulation by some effectors depends on the presence of a signal peptide. These findings highlight that effector function can go beyond predictions based only on expression profiles.

bioRxiv Molecular Biology@biorxiv-molbio.bsky.social · last yr.

Functional Characterization of Zymoseptoria tritici Candidate Effectors Reveals Their Role in Modulating Immunity in Nicotiana benthamiana https://www.biorxiv.org/content/10.1101/2025.05.20.655180v1

One week ago, I successfully defended my Ph.D. dissertation! I'm deeply grateful to my advisors, mentors, and all the amazing scientists whose insights and support shaped this journey. And of course, thanks to Zymoseptoria—such a fascinating fungus to study! ☺️

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Very excited with @tobybarilbio.bsky.social to share this preprint about his latest work on TEs! We knew that TEs were very pretty active in this global fungal pathogen of wheat. Now with nearly 2000 Illumina genomes available, we could finally ask questions about historic TE activation waves.

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Toby Baril@tobybarilbio.bsky.social · 2y ago

Excited to share our latest preprint 🥳 Historic transposon mobilisation waves create distinct pools of adaptive variants in a major crop pathogen @danielcroll.bsky.social #TESky www.biorxiv.org/content/10.1...