What if we could locate, sequence, and identify every protein in a cell? This would unlock a transformative way to study biology and disease. That question shaped my PhD, and I’m excited to share our new preprint on the Principles of In Situ Protein Sequencing, now live on bioRxiv.

bioRxiv Biochemistry@biorxiv-biochem.bsky.social · 9mo ago

Principles of in situ protein sequencing: expansion microscopy-adapted Edman degradation and amino acid recognition https://www.biorxiv.org/content/10.64898/2026.01.29.702630v1

New preprint out! www.biorxiv.org/content/10.6... One of the most salient lessons I learned in all my adventures with screening and protein engineering is the importance of context. The context in which you test a gene or protein determines what function it has.

bioRxiv Bioengineering@biorxiv-bioeng.bsky.social · 9mo ago

Library transgenesis in zebrafish through delayed site-specific mosaic integration for in vivo pooled screening of transgenes https://www.biorxiv.org/content/10.64898/2026.01.30.702415v1