New preprint out! www.biorxiv.org/content/10.6... One of the most salient lessons I learned in all my adventures with screening and protein engineering is the importance of context. The context in which you test a gene or protein determines what function it has.

bioRxiv Bioengineering@biorxiv-bioeng.bsky.social · 6mo ago

Library transgenesis in zebrafish through delayed site-specific mosaic integration for in vivo pooled screening of transgenes https://www.biorxiv.org/content/10.64898/2026.01.30.702415v1

Principles of in situ protein sequencing: expansion microscopy-adapted Edman degradation and amino acid recognition https://www.biorxiv.org/content/10.64898/2026.01.29.702630v1

What if we could locate, sequence, and identify every protein in a cell? This would unlock a transformative way to study biology and disease. That question shaped my PhD, and I’m excited to share our new preprint on the Principles of In Situ Protein Sequencing, now live on bioRxiv.

bioRxiv Biochemistry@biorxiv-biochem.bsky.social · 6mo ago

Principles of in situ protein sequencing: expansion microscopy-adapted Edman degradation and amino acid recognition https://www.biorxiv.org/content/10.64898/2026.01.29.702630v1

🎉 #SMPS4 Group Photo! 🎉 A huge thank you to all the brilliant minds who joined us and made this event unforgettable. Your passion and insights are what drive this community forward. Here's to pushing the boundaries of science together! 🧬✨

We learned so much from Camille Mitchell's session about:Towards in situ protein sequencing with Expansion Microscopy using in-gel Edman degradation and N-terminal amino acid binders #SMPS4