Shaili Mathur
@shaili-mathur.bsky.social
Biology PhD student @ Stanford w. Dmitri Petrov and Jonas Cremer
Don’t miss the deadline (Oct 31) if you want to apply for a faculty position in Evolutionary Biology in my department! facultypositions.stanford.edu/jobs/assista...
Assistant Professor in Evolutionary Biology - Stanford University, California, United States
The Department of Biology at Stanford University seeks applicants for a tenure-track Assistant Professor in Evolutionary Biology. A successful candidate will conduct research that asks fundamental que...
facultypositions.stanford.edu
Excited to share our new preprint where we ask: How does temp alter susceptibility to kanamycin, selection and spread of resistance in E. coli with the plasmids R1 and RP4. tl;dr AMR @ high temp is due to higher growth rates and susceptibility, increasing selection. www.biorxiv.org/content/10.6...
I’m excited to share our new preprint, where we ask: to what extent can evolution in fluctuating environments be predicted? Spoiler: far more than the strong history-dependence of fitness would suggest! www.biorxiv.org/content/10.6...
Order invariance of fitness makes evolution predictable despite strong history-dependent effects
Environmental change is ubiquitous in nature, yet understanding its effect on the predictability of evolution remains a challenge. Previous work in microbes has shown that growth and fitness in a part...
biorxiv.org
New Perspective w/ @petrovadmitri.bsky.social and Paul Schmidt! We ask what evolution-in-action studies tell us about an old question: what genetic variation matters for fitness, and what maintains it? ecoevorxiv.org/repository/v...
Common, consequential, and actively maintained: a neo-balance view of genetic variation
ecoevorxiv.org
I’m excited to share our preprint with @oliviamghosh.bsky.social, where we explore what it takes to ‘win’ in long-term evolutionary competition: www.biorxiv.org/content/10.1...
Adaptive evolution can overwrite initial natural fitness variation only in highest-fitness yeast isolates
The fitness of an organism determines its likelihood of succeeding in short-term competition, but many other factors can influence its long-term success. In this study, we investigate the relative con...
biorxiv.org
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential. www.biorxiv.org/content/10.1...
Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation
The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and n...
biorxiv.org