uchicago.wd5.myworkdayjobs.com/External/job... The Kreiner and Carley Lab groups are hiring a shared Research Analyst to help lead wet lab protocol development and management. We're a fun group and would love to hear from you :) Get in touch with questions!

Research, Analyst

Department BSD E&E Carley Lab About the Department The Kreiner Lab (kreinerlab.com) and Carley Lab (carleylab.uchicago.edu) in the Department of Ecology & Evolution at The University of Chicag...

uchicago.wd5.myworkdayjobs.com

Cannot be more excited about the lineup for the inaugural Function of Evolving Systems GRC conference I am co-organizing with the amazing Joy Bergelson. Less than a month away: August 9 - 14, 2026. Still a few spots left! And do check out the amazing list of speakers: www.grc.org/function-of-...

Do you love amplicon sequencing? Do you want to sequence MORE amplicons, faster and at lower cost? Check out 💘CUPID-seq💘, a highly multiplexed library design that lets you sequence hundreds of amplicon samples (16S, 18S, and more!) on a single sequencing run! (1/n) 🧵 www.biorxiv.org/content/10.6...

We are pleased to recognize two Honorable Mentions for the SSE Presidents’ Award this year: Skylar Berardi and Miles Roberts for their papers in Evolution Letters! shorturl.at/CpcoY @evolletters.bsky.social

I am excited to share our latest paper, Uniform bacterial genetic diversity along the gut, now out in Nature Communications! www.nature.com/articles/s41.... (1/n)

Really excited that this major work from my PhD is finally published in @plosbiology.org ! In it, we were trying to tackle a fundamental question in evolution - how do genetic mutations map onto evolutionary fitness? (1/n) journals.plos.org/plosbiology/...

Genotype-fitness mapping of adaptive mutants reveals shifting low-dimensional structure across divergent environments

Predicting the effect of a genetic mutation on fitness is a major challenge in evolutionary biology. This study uses fitness effects of a large collection of adaptive yeast mutants in multiple lab env...

journals.plos.org

Have you ever wondered 🤔... Does phenotypic variance respond to environmental perturbation? Does it have a genetic basis? Are mean and variance regulating loci exposed to different selection pressures? These and more questions are explored in our new preprint 🔥 www.biorxiv.org/content/10.6...

I am seeking a postdoc to join my group at UCLA -- ideally the candidate would have some experience in either population genetics or microbes/microbiome (computational background needed). We have a range of projects and are happy to tailer to your interests. Please dm/email me if interested.

Scientists across the career spectrum are burnt out, & people are leaving STEM in startling numbers, particularly those from under-represented groups. A lab handbook can foster a more positive research culture. By @scattercushion.bsky.social @nature.com 🧪 www.nature.com/articles/d41...

Lab morale got you down? Try a handbook

Documents that lay out a research group’s ethos and practical guidelines are becoming increasingly popular in the academic community.

nature.com

Very excited to be going to the Annual Drosophila Research Conference @genetics-gsa.bsky.social in Chicago this March. I think #Dros26 is the hashtag. There is still time for you to register! The fly community is so welcoming and supportive—if you are new to flies please consider going.

Excellent piece by Matz @heatshok.bsky.social and colleagues discussing the dire status of Caribbean reefs, and potential plans and policies that can be implemented if these reefs are to have any chance. Check it out in PNAS!

Registration is open for the inaugural GRC conference in the Function of Evolving Systems. Aug 9-14, 2026, Waterville Valley. Truly stellar speaker lineup. Student/postdoc fellowships are available! Please come join us! www.grc.org/function-of-... @joybergelson.bsky.social

How does the strength of genetic drift evolve over long times? New preprint out 👇 www.biorxiv.org/content/10.6...

Excited that SpaceBar is now out in Nature Methods!🥳 We combined clone tracing with spatial transcriptomics to untangle what drives gene expression in tumors: a cell's identity or its neighborhood? Most genes were driven by location, but some showed strong clonal patterns. rdcu.be/eVhpc

SpaceBar enables single-cell-resolution clone tracing with imaging-based spatial transcriptomics

Nature Methods - SpaceBar is a cellular barcoding strategy for simultaneous analysis of cell clonal and spatial identities.

rdcu.be

Working on this paper fundamentally changed how I thought about bacterial evolution, and I couldn't ask for a better to Hannukah present than to see it out, at last!

Nandita Garud@nanditagarud.bsky.social · 8mo ago

Grateful to share our paper on gene-specific selective sweeps in human gut microbiomes, now out in Nature! It has been a joy to work with @rwolff.bsky.social, whose insights and hard work made this possible. www.nature.com/articles/s41...

If you are interested in this work and are looking for a postdoc position, please get in touch -- we are actively looking for someone to join our group at UCLA!

Grateful to share our paper on gene-specific selective sweeps in human gut microbiomes, now out in Nature! It has been a joy to work with @rwolff.bsky.social, whose insights and hard work made this possible. www.nature.com/articles/s41...

Gene-specific selective sweeps are pervasive across human gut microbiomes - Nature

Development and application of the integrated linkage disequilibrium score (iLDS) reveals both selective pressures impacting the human gut microbiome and the mechanisms by which gut bacteria adapt to ...

nature.com

So excited to share this work led by @alexrob.bsky.social with Ben Kerr! We investigated a poliovirus capsid inhibitor that exploits a breakdown in the genotype-phenotype map to prevent drug resistance evolution. Or does it? See Alex's thread, but a few extras: #socialviruses #evosky #virosky 🧪

Alexander Robertson@alexrob.bsky.social · 8mo ago

My first lead author paper is out with Ben Kerr and @alisonfeder.bsky.social! We found that making an antiviral too strong can sometimes make resistance easier to evolve. This has implications for how we design drugs, choose doses, and think about viral evolution in the face of treatment. (1/n)

Genuinely one of the most important and interesting papers I have been a part of! Relevant to fundamental questions regarding the predictability of adaptation, as well as the applications of genomic data. Congrats to @j-smiley-rhodes.bsky.social and all co-authors for such a masterpiece!

Jess Smiley-Rhodes@j-smiley-rhodes.bsky.social · 9mo ago

Thrilled to finally share the magnum opus of my PhD that focuses on the genetic basis of evolutionary change! Specifically, we know we can map the genetic basis of a trait, but can we tell which genes will underlie the trait shift when it evolves? doi.org/10.1101/2025...

Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n) www.biorxiv.org/content/10.1...

One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential. www.biorxiv.org/content/10.1...

Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation

The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and n...

biorxiv.org

One week to apply for our fully funded PhD position in Norway! This is a really exciting project in collab. with University of Helsinki and Benchmark Genetics. Samples are ready - you do (read: learn) everything - functional genomics, bioinformatics, genotype-phenotype associations 🤩 Please RT!

Jukka-Pekka Verta@jpverta.bsky.social · 12mo ago

How do regulatory genes control alternative life histories? We have an open PhD position to answer this question using functional genomics in Atlantic salmon. Apply by October 15th through www.jobbnorge.no/en/available... Please share widely! 🧬🦑🖥️

Human-mediated land-use and climate change occur simultaneously, but how do they interact to shape adaptive dynamics? Super excited to share the first paper from the Kreiner lab, led by postdoc extraordinaire @rpineau.bsky.social

bioRxiv Evolutionary Biology@biorxiv-evobio.bsky.social · 10mo ago

The genomic response to drought across spatiotemporal scales in Amaranthus tuberculatus https://www.biorxiv.org/content/10.1101/2025.10.02.679894v1

New preprint led by undergrad Owen Moosman! We uncover extensive haplotype diversity in antifreeze protein gene copy number in polar Zoarcoidei fishes, and report new tools to evaluate assembly uncertainty and switch error in phased genomes www.biorxiv.org/content/10.1...

Very excited to see this work in press! I think there is a reason to believe that this is a common means of stabilizing large-effect polymorphisms in general and might be an important reason for why diploidy is so common. news.stanford.edu/stories/2025...

Classic recessive-or-dominant gene dynamics may not be so simple

New fruit fly research provides the first direct evidence of “dominance reversal,” revealing why pesticide resistance is so hard to eliminate in changing environments.

news.stanford.edu

Marianna Karageorgi@mkarag.bsky.social · 2y ago

How is functional variation at large-effect loci maintained in natural populations? Thrilled to share our work showing how beneficial dominance reversal helps fruit flies maintain a resistance polymorphism as selection varies in their environment! A thread 🧵 1/n www.biorxiv.org/content/10.1...

How do populations maintain an evolutionary memory? I am happy to share that our work with Dmitri Petrov @petrovadmitri.bsky.social, Paul Schmidt, and colleagues on dominance reversal and stabilization of insecticide resistance in changing environments over time is now published at Nature EE.

Beneficial reversal of dominance maintains a large-effect resistance polymorphism under fluctuating insecticide selection - Nature Ecology & Evolution

Measuring selection and dominance in fitness of the insecticide-resistant Ace alleles in Drosophila melanogaster, the authors show evidence for beneficial reversal of dominance, a mechanism that can s...

nature.com

Check out our paper in Evolution Letters! We used D. melanogaster pigmentation as a focal trait to explore parallelism in phenotypic and genomic responses to environmental change - read more at the link below 👇

Evolution Letters@evolletters.bsky.social · last yr.

How predictably does complex trait adaptation proceed over space and time in wild populations? doi.org/10.1093/evle... Now in @evolletters.bsky.social by @skylerberardi.bsky.social, @paulrschmidt.bsky.social et al. 📷: Dr. Rush Dhillon

I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!

Come join us at UCLA!!! We have a growing population genetics community here and Nandita and her lab are outstanding!

Nandita Garud@nanditagarud.bsky.social · last yr.

I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!

The Xue lab at UC Irvine is looking for a staff scientist to support our work investigating how microbes interact and evolve in the gut microbiome! Open to a wide range of previous experience levels, see ad for more. recruit.ap.uci.edu/JPF09601

Junior, Assistant, or Associate Specialist – Xue Lab

University of California, Irvine is hiring. Apply now!

recruit.ap.uci.edu