Having a reflective evening as I mull over a conference abstract rejection. Did the abstract hit the wrong note? Did it not tell an interesting story? Did I somehow get the message wrong? Should I care? I've had plenty journal submissions desk rejected in minutes. Never a poster abstract...

In a recent study, pupils using AI saw their average homework score rise by 18% across all subjects after six months. But come exam time, the same students scored 20% below their classmates who had not called on AI’s help. We analyse the data

Does AI stop children from learning?

New data show the peril and promise of the technology

bit.ly

journals.sagepub.com/doi/full/10.... Articles like this provide useful insight to the real world. I suspect the UK (sorry 🏴󠁧󠁢󠁥󠁮󠁧󠁿) has even more data on switching. We lack some outcome info. I bet clinicians wouldn't mind providing that if it was for use...

Sage Journals: Discover world-class research

Subscription and open access journals from Sage, the world's leading independent academic publisher.

journals.sagepub.com

Probably 18 months ago - maybe more - the fabulous team at #OpenPrescribing shared their beta of Open Hospital Prescribing one of the first things I did was take a look at CDK4/6i use to see if there was a noticeable shift in use - post OS data being published. Since then - we've been working on 👇🏻

Anyone would think that dropping the FMD to claim a Brexit win had been a stupid idea. But you'd also think that if barcodes really made a difference to workflow, then market forces would push it to happen? Take a look at Aldi and Lidl packaging...

The Pharmaceutical Journal @pharmaj.bsky.social · 2w ago

The government is looking into which barcodes are required on medicines packaging, the Department of Health and Social Care has confirmed #ukpharmacy #druglabelling #communitypharmacy pharmaceutical-journal.com/article/news...

I've written to 'Thr Oncologist' because I think it's really important we try to keep the record clear - if there is an interaction with PPIs and palbociclib, the only evidence if for the old capsule formulation. doi.org/10.1093/onco... If we get generics and they are capsules that could matter.

Proton-Pump Inhibitor use in combination with a CDK4/6 inhibitor: Is formulation the issue?

Calum Polwart; Proton-Pump Inhibitor use in combination with a CDK4/6 inhibitor: Is formulation the issue?, The Oncologist, , oyag293, https://doi.org/10.1

doi.org

www.bbc.co.uk/news/live/cg... Yvette Cooper takes the poison chalice of Health Secretary.

Healey appointed chancellor and Miliband becomes foreign secretary as Andy Burnham picks cabinet

Meanwhile Shabana Mahmood will stay on as home secretary as new Prime Minister Andy Burnham forms his top team.

bbc.co.uk

Wow. Just wow. @jamadermatology.com publish a case series on Vitamin D in oncodermatology. doi.org/10.1001/jama... If ever there was an article for a journal club to dismantle... It is this!

High-Dose Oral Vitamin D for Toxic Effects of the Skin Associated With Chemotherapy and Radiation

This case series evaluates the clinical response, safety profile, and time to improvement for high-dose oral vitamin D in patients with toxic erythema of chemotherapy and acute radiation dermatitis.

doi.org

Oh interesting 10.1001/jamaoncol.2026.2191 ct-DNA in resected liver mets. OK it's retrospective analysis. But as you might hope, ctDNA at resection is a bad sign. Negativity is a good sign But there is an additional hidden info...

www.bbc.co.uk/news/article... My mind is blown. It feels like a sketch from Yes Minister! "Repay the generosity of the British people". You'd almost think that was the concept of taxation. That as those people earn they pay it forward? And as for this sentence 👇🏻

Refugees will be told to repay £10,000 under new asylum rules

Ministers will be given powers to recover costs from adults who have received asylum support under new laws.

bbc.co.uk

The NYT says "it was too good to be true". They are right. Biologically it seemed implausible. A drug with a massive half life. With randomisation only apply to the first few doses. And now a load of research integrity questions. www.nature.com/articles/s41...

www.cnn.com/2026/05/22/u... Wow. I've spent a bit of time looking at patient level data and explaining why we need to only publish aggregate data not "anonymous" data. People think I'm mad when I say "in theory... You could recreate xyz"...

A PDF let the internet hear the final words in the cockpit of a UPS plane as it crashed. The NTSB now wants it taken down | CNN

New technology allowing audio of plane crashes to be extracted from still images has prompted the National Transportation Safety Board to take a rare step of pausing the public release of nearly all i...

cnn.com

I never quite understand why in this country when this happens... People just carry on... But in the US this would result in a full shutdown. That said. I don't understand why a contract can't be ready.

The Pharmaceutical Journal @pharmaj.bsky.social · 5mo ago

The ‘Community pharmacy contractual framework’ for 2026/2027 will not be in place for the start of the financial year, Community Pharmacy England has announced #ukpharmacy #communitypharmacy

Biosimilar Competition in Oncology—Beyond Insurer Pressure url: jamanetwork.com/journals/jam... Will need digestion before I comment... ...let's just say... The UK ain't on 45% at 5 years!

Biosimilar Competition in Oncology—Beyond Insurer Pressure

The high price of drugs continues to be the focus of policy discussions, with attention often drawn to the importance of promoting price competition through the use of generic and biosimilar versions ...

jamanetwork.com

www.bbc.co.uk/news/article... Would take me seconds as PM to withdraw permission and tell them to get off my land.

Trump says Starmer is 'no Winston Churchill' over Iran strikes

Sir Keir Starmer had refused to grant the US permission to use the Diego Garcia military base.

bbc.co.uk

Cancer patients ditch NHS for private chemotherapy share.google/fKKhDJVQqyrf... 12% ⬆️ from 2021 to now. So if I did my maths right.. is less than a 2.9% annual increase in activity. While the NHS thinks chemo activity increases 6-8% annually. In other words.. private sector under delivering

Feels nuts that this is even a standard! Time critical... 24 hours...

The Pharmaceutical Journal @pharmaj.bsky.social · 6mo ago

NHS England has said that patients in emergency or acute hospital departments should have all their time-critical medicines identified and prescribed, including a plan for pharmacy review, within 24 hours of admission #ukpharmacy #time-criticalmedicines #hospital

Wow news.stv.tv/scotland/ban... Charlie must be desperate to be seen as a man of the people for some reason at the moment... Last I heard they hadn't actually won the final.

Bank holiday confirmed in Scotland for Monday after World Cup opener

The Tartan Army will be able to celebrate into the wee hours on Sunday, June 14, after a one-off bank holiday was granted by the King

news.stv.tv

New to #RPSLibrary: Neonatal Formulary: Drug Use in Pregnancy and the First Year of Life – 9th ed. (2026) Read it here: https://ow.ly/5Bmj50Y62pR under ‘Pediatrics'

Hobbycraft issues full recall of asbestos-tainted children’s play sand

Hobbycraft issues full recall of asbestos-tainted children’s play sand

Craft retailer says there is ‘risk to health’ after some vials in Giant Box of Craft set contained fibrous tremolite asbestos Hobbycraft has issued a full recall of children’s coloured play sand after confirming some bottles contained asbestos, presenting “a risk to health”. The Guardian revealed at the weekend that the craft retailer had stopped selling the kit after being alerted to the risk but had stopped short of alerting customers who had already bought the item. Continue reading...

theguardian.com

Just remembering Jan 25th about 10 years back. Explaining to my colleague who last I heard was now CEO of a major Hospital Group in 🏴󠁧󠁢󠁥󠁮󠁧󠁿 about #Haggis Hunting. For those who don't know the chap on the right is a vegetarian #Haggis & the lady on the left with her two kids are carnivore #BurnsNight 🏴󠁧󠁢󠁳󠁣󠁴󠁿🥃

jamanetwork.com/journals/jam...

Immune Checkpoint Inhibitor–Associated Cardiovascular Toxic Effects

This Special Communication outlines the International Cardio-Oncology Society position on immune checkpoint inhibitor–associated cardiovascular toxic effects.

jamanetwork.com

www.bbc.co.uk/news/article... Now I may be missing the point here... BUT... If you were a Conservative MP who had a vote in parliament and you now say Conservatives ruined Britain... Why does changing which 🏵️ you are wearing make you electable at the next election? Jenrick was a Conservative.

Robert Jenrick joins Reform UK after being sacked by Tories

The former minister says the Conservatives

bbc.co.uk

spcare.bmj.com/content/earl... Further reinforcement that H2 antagonists are not necessary with Paclitaxel.

H2-antagonists in paclitaxel premedication: systematic review and meta-analysis

This systematic review and meta-analysis aimed to investigate the necessity of histamine-2 antagonists (H2As) in paclitaxel premedication protocols, particularly in preventing hypersensitivity reactio...

spcare.bmj.com

Big thoughts today... I'm behind on opening my advent calendar... ...does that make Christmas come later?

A UK-first guideline has recommended that all patients should have pharmacogenetic testing to identify clinically relevant CYP2C19 genetic variants, regardless of indication #ukpharmacy #pharmacogenomics #bloodclots

All patients should undergo pharmacogenetic testing before being prescribed clopidogrel

A UK-first guideline has recommended that all patients should have pharmacogenetic testing to identify clinically relevant CYP2C19 genetic variants, regardless of indication. The clinical guideline,…

buff.ly

Mostly 📌 this here so I can read it in detail later. BUT my immediate thoughts are we usually struggle to agree what is 100% right when comparing human Vs human on MMM tasks. So human Vs LLM? If you get 80% correct, will that mean there is at least one error for every patient who has polypharmacy

medRxivpreprint@medrxivpreprint.bsky.social · 9mo ago

Rx-LLM: a benchmarking suite to evaluate safe LLM performance for medication-related tasks https://www.medrxiv.org/content/10.64898/2025.12.01.25341004v1

www.telegraph.co.uk/news/2025/11... They say your 1st job gives you life skills. I hope these 1700 kids are currently learning skills about redundancy payments and legal requirements for consulting etc. One of them must have a lawyer dad(or mum)... Off to 👩🏻‍⚖️.. (Legally required to consult for 30d)

“While you are on chemotherapy …” Myths: - Avoid large social gatherings - Wash clothes w body fluids STAT - Use a separate toilet - Avoid all EtOH - Avoid certain foods, coffee --> lack evidence, cause harm academic.oup.com/jnci/article... great article from @csoncol.bsky.social #oncology

“While you are on chemotherapy …”: common recommendations that lack evidence and may cause harm

Abstract. Patients on chemotherapy often use multiple resources to obtain information on wide-ranging issues, including prognosis, treatments, diet, exerci

academic.oup.com

www.ft.com/content/5d6f... Wow. Rarely do I see a comments section so polarised. "Charitable" sponsorship offering "access" to key people is dodgy in my eyes. It's interesting sitting on the sidelines watching this stuff. Having previously been among it. You don't see conflict you are among

UK military top brass mix with defence executives at luxury Alpine event

Details of armed forces and industry attendees at Méribel competition raise concerns about conflicts of interest

ft.com