We reengineered the TIR-Learner for 60-100 times faster de novo search of Terminal Inverted Repeat transposons. We completed annotating 579 vertebrate genomes in 4 hours! Kenji Gerhardt did all the heavy lifting for this "side project".
TIR-Learner v4: Accelerated annotation of terminal inverted repeat transposons https://www.biorxiv.org/content/10.64898/2026.07.21.739826v1