It’s an inversion of liberty to deny citizenship to people who have overcome so much, it’s a betrayal of the American experiment

Sarah Betancourt@sweetadelinevt.bsky.social · 8mo ago

“She showed up as scheduled, and when she arrived, officers were asking everyone what country they were from, and if they said a certain country, they were told to step out of line and that their oath ceremonies were canceled.” www.wgbh.org/news/local/2... @gbhnews.bsky.social

ok I have a mystery. What is the food ingredient “inland sea water powder”?

I am once again reminded that the loudest person in the room is not necessarily the smartest or most qualified

Reader, we would not like a dictator in the “land of the free and home of the brave”

Aaron Rupar@atrupar.com · 12mo ago

Trump: "A lot of people are saying maybe we'd like a dictator."

Delighted to present our second paper of the year. This one explores the molecular mechanism of TTP, a key post-transcriptional regulator of AU-rich mRNAs. Work led and coordinated by @filippekovic.bsky.social, in collaboration with Perry Blackshear. www.nature.com/articles/s41...

Multivalent interactions with CCR4–NOT and PABPC1 determine mRNA repression efficiency by tristetraprolin - Nature Communications

Deadenylation leads to mRNA decay, with PABPC1 protecting the poly(A) tail, while tristetraprolin and CCR4–NOT promote deadenylation. Here, the authors describe how these three proteins interact to re...

nature.com

I remember when OS updates were like "we will protect your computer from viruses and make it faster" and now they lead with

Paper 2 -- Translational co-regulation detected in mammalian cells www.nature.com/articles/s41... A deeper explanation of the human story, scientific conclusions, and Github/Zenodo links to use the pre-trained models: www.linkedin.com/feed/update/...

Translation efficiency covariation identifies conserved coordination patterns across cell types - Nature Biotechnology

Matched ribosome profiling and RNA sequencing data quantify translation efficiency patterns across 140 human and mouse cell lines.

nature.com

Very excited that our most significant work, a collaboration w/ Dr. Can Cenik at UT Austin on translational gene regulation, was finally published in Nature Biotechnology in a dual set of studies: Paper 1 -- an AI model trained to predict translation rates from mRNA sequences: rdcu.be/exN1l

Predicting the translation efficiency of messenger RNA in mammalian cells

Nature Biotechnology - A deep convolutional neural network model predicts the influence of the full-length mRNA sequence on translation efficiency.

url.de.m.mimecastprotect.com

Another example of spurious effects when you try to interpret RNA biology from DNA introduced into cells without confirming exactly what RNA processing is happening. Important and common confounder - great paper!

DjuranovicLab at Brown University RNA Center@djuranoviclab.bsky.social · last yr.

Our collaboration with Tony Mustoe's lab us out today. MPRA libraries and possible cryptic splicing in MPRA reporters, or reporters in general. The additional novelty here is that such events are controlled or influenced by AU-rich sequences. www.nature.com/articles/s41...

“With these considerations, we expect to fund through the 4th percentile.” There it is, in black and white, the destruction of cancer research in the US.

Edwin Antony@professorantony.bsky.social · last yr.

Funding policy for 2025 from NCI. Was just released: 4 percentile…maybe! www.cancer.gov/grants-train...

apropos of nothing, a strong rec for “The Tyranny of Merit”, in which Sandel notes a putative meritocracy “fosters a sense of entitlement among the successful while humiliating those who do not succeed, ultimately undermining the common good and social solidarity” bookshop.org/p/books/the-...

The Tyranny of Merit: Can We Find the Common Good?

Can We Find the Common Good?

bookshop.org

this is an example of the so-called meritocracy that’s threatened by introspection on who gets into college and why

NYTimes: affirmative action for mediocre editors angry at MeToo@originalist.bsky.social · last yr.

"Nearly half of white students admitted to Harvard between 2009 and 2014 were legacy students or Dean’s Interest List—a list of applicants whose relatives have donated to Harvard, the existence of which only became public knowledge in 2018" 75% of them would not have been admitted otherwise

great review on the myriad ways that genetic variation in mRNA untranslated regions can cause disease!

Nicky Whiffin@nickywhiffin.bsky.social · last yr.

Ever craved a review that details the diverse mechanisms through which UTR variants have been show to cause rare disease??? Or maybe just curious? Well this review, written by the amazing Dr @nechamawieder.bsky.social , is for you 🤓🧬🩺

This July 4 I celebrate my country born by separation from a tyrannical king, with the principles that all people are created equal and that the government represents the will of the People, not a monarch. The unalienable rights of Life, Liberty, and the pursuit of Happiness. Let freedom ring!

Zohran Kwame Mamdani@zohrankmamdani.bsky.social · last yr.

America is beautiful, contradictory, unfinished. I am proud of our country even as we constantly strive to make it better, to protect and deepen our democracy, to fulfill its promise for each and every person who calls it home. Happy Independence Day. No Kings in America.

absolutely love this new tour of the cosmos using the Skyviewer app built using new images off the Vera Rubin telescope - gorgeous and great explanations skyviewer.app/tours

whenever I need some sunshine I turn to cientotres 103.1 FM out of San José, Costa Rica radios-de-costa-rica.com/1031-fm

A federal judge on Monday declared the Trump administration’s move to cut hundreds of grants issued by the National Institutes of Health illegal, accusing the government of discrimination against minorities and L.G.B.T.Q. individuals. nyti.ms/4jSIjOG

Trump’s Cuts to N.I.H. Grants Are Illegal, Federal Judge Rules

The judge accused the Trump administration of discriminating against minorities and L.G.B.T.Q. people and ordered the government to restore much of the funding.

nyti.ms

the story today is of a profoundly low energy military parade being met with millions of americans in nationwide protests denouncing the dictatorial pretensions of the president

Traveling for a soccer tournament and there’s a rally of maybe 500 people here in South Lake Tahoe today, too. Solidarity. No kings, no tyrants 🇺🇸

Dave Levitan@davelevitan.bsky.social · last yr.

Dude's wanted a military parade for himself for years and he finally makes it happen and turnout is worse than at a medium sized city's farmers market on a rainy day while like 2% of the entire country went out to protest his bullshit

Racism and xenophobia is already turning the US into a backwater to avoid

people will literally die because of this

Carl Zimmer@carlzimmer.com · last yr.

“Covid-19 deniers, skeptics and outright anti-vaccine individuals.” Meet the government's new vaccine advisors. Story by @sherylnyt.bsky.social Gift link: nyti.ms/4462vqO

"all the best" 💩🤡

Elizabeth Villa@thevillalab.bsky.social · last yr.

I urge others to similarly support our patriots at NIH who use their training and talents to improve human health and position the US as the world’s leader in biomedical discovery, innovation and technology development 🙏

Stanford AAUP@stanfordaaup.bsky.social · last yr.

Stanford's professor and Bethesda Declaration signatory @carolynbertozzi.bskyverified.social notes that the declaration “represents the voices of the highly trained Americans at NIH who want to serve their country and steward the biomedical enterprise.” 🧪 www.science.org/content/arti...

fully agree - the real question is: will Trump let the DOGEs out?

Terry McGlynn@hormiga.bsky.social · last yr.

In full sincerity, now is the moment to emphasize that undoing the changes implemented by DOGE is good for America, and increasing investment into NASA, NSF, NIH and other agencies will keep Elon from profiting off taxpayers.

These are not just grants. This is thousands of people who devoted their lives and careers - taking pay cuts, working long hours, living with uncertainty - all for the chance to try to make people's lives a bit better for you and your loved ones. This breaks my heart.

Joshua Tucker@jatucker.bsky.social · last yr.

Cutting NIH or NSF funding sounds abstract. Seeing what research is actually being cut makes it real. Kudos to @nytimes.com for this piece: www.nytimes.com/interactive/...

local yay area man discusses choices, when to go (dumb), how to be sprinkled with game, and gouda + broccoli

NPR@npr.org · last yr.

Bay Area ambassador E-40 packs in three decades worth of hits at the Tiny Desk for Black Music Month.

if the US wants to be competitive on the world stage, investing in education, science, and technology is the way. one doesn’t simply discriminate your way to the top

Stand Up for Science!@standupforscience.net · last yr.

McCarthyism 2.0: Now with added racism. Trump wants to purge Chinese students from U.S. universities under the guise of “national security.” This isn’t defense — it’s discrimination, plain and simple. We stand up for international students. www.politico.com/news/2025/05...

prelim phase 1/2 trial results of the Moderna H5N1 vaccine program included no (none) dose-limiting toxicity and 97.8% (NINETY SEVEN POINT EIGHT PERCENT) of participants reaching protective antibody levels. defunding this program makes America sicker endpts.com/trump-axes-m...

Helen Branswell 🇨🇦@helenbranswell.bsky.social · last yr.

BREAKING: In a serious blow to US pandemic flu preparedness, HHS has cancelled a contract with Moderna to test and license prototype vaccines for #H5N1 #birdflu and other potential pandemic viruses. In a pandemic, mRNA is the fastest way to vaccine doses. www.statnews.com/2025/05/28/m...

Thinking of this @propublica.org reporting today about stillbirths of unvaccinated parents during the Delta wave, before CDC had explicitly recommended COVID vaccines for pregnant people and the damage the virus did to the placentas. www.propublica.org/article/covi...

“God, No, Not Another Case.” COVID-Related Stillbirths Didn’t Have to Happen.

A lack of testing data and government guidance led many to avoid the COVID-19 vaccine during pregnancy, unwittingly increasing their chances of a stillbirth.

propublica.org

Maggie Astor@maggieastor.bsky.social · last yr.

A huge step from HHS that is at odds with science showing significant risks for young children and pregnant women — and that directly contradicts *the FDA's own publication* from last week listing pregnancy as a high-risk condition that would qualify people for this fall's Covid vaccine

today’s anti-vaccination, pro-disease decision by RFK in the Orwellian name of “making America healthy again” will lead to more moms dying and more unhealthy babies why anyone would choose to not protect moms and babies as best we can is beyond my comprehension

Emily R Smith, ScD, MPH@dremilyrsmith.bsky.social · last yr.

🤰 Among pregnant women, those who get COVID are more likely to die or end up in the ICU. And their babies are more likely to be born too soon or too small. (BMJ Global Health Paper here: gh.bmj.com/content/8/1/...)