www.biorxiv.org/content/10.6... Local fluidization of an active cytoplasmic gel partitions large cells
Can mathematics explain how biological patterns are formed? Alan Turing thought so. Join me, @benswedlund.bsky.social, as we explore his reaction-diffusion theory and how it transformed our understanding of pattern formation and self-organisation.
Excited to share my first preprint from my PhD work in the Bement lab 🥳 💝 We discovered a previously unrecognized function of the RhoGAP RGA-3/4: RGA-3/4 directly and cooperatively binds to F-actin and reorganizes it by crosslinking actin filaments www.biorxiv.org/content/10.6...
Molecular and cellular characterization of the interaction between the Rho GAP RGA-3/4 and F-actin
During cytokinesis in amphibian and echinoderm embryos, propagating waves of Rho activity and F-actin assembly - cortical excitability - are amplified and focused at the equatorial cortex by the mitot...
biorxiv.org
📢 Pre-print alert 📢 We are excited to share the lab's first research article! We used our artificial cortex system to investigate how membrane composition regulates self-organized cortical dyanamics. Check it out here: www.biorxiv.org/content/10.1...
Membrane composition-dependent patterning of Rho and F-actin in an artificial cell cortex
Cortical excitability, a phenomenon in which the cell cortex is dynamically patterned with waves of F-actin assembly, has been described in a variety of animal model systems, including embryos of mamm...
biorxiv.org
