How can Bayesian methods help us learn more from Studies Within A Trial (SWATs)? Find out more here where we explore how Bayesian methods and ACCEPT analysis can help us get more meaningful insights from SWATs: link.springer.com/article/10.1... #Trials #TrialMethodology #SWAT #BayesianStatistics

The use of Bayesian methods for the analysis of Studies Within A Trial: a proof-of-concept case study - Trials

Background and Aims A Study Within A Trial (SWAT) is a research study embedded within a larger trial which aims to investigate different strategies for a particular trial process, such as trial recrui...

link.springer.com

📣New Publication: Investigating estimand considerations in adaptive trials: a systematic review link.springer.com/article/10.1...

Investigating estimand considerations in adaptive trials: a systematic review - Trials

Background Randomised controlled trials (RCTs) are the gold standard for evaluating treatment effects, with the results informing policy and clinical practice. To ensure appropriate methods are utilis...

link.springer.com

Investigating estimand considerations in adaptive trials: a systematic review by @statsci.bsky.social link.springer.com/article/10.1...

Investigating estimand considerations in adaptive trials: a systematic review - Trials

Background Randomised controlled trials (RCTs) are the gold standard for evaluating treatment effects, with the results informing policy and clinical practice. To ensure appropriate methods are utilis...

link.springer.com

🥳 We are thrilled to celebrate Jack Elkes, who has successfully defended his PhD on, Improving the evaluation of digital mental health interventions in randomised controlled trials by understanding and incorporating user engagement. Congratulations Jack! 🥳

To read their full article please see here: lnkd.in/epiZdzWB

Last week we enjoyed @vcornelius.bsky.social Inaugural lecture! Under pressure: smarter trials for better health outcomes - covering traditional trials to Bayesian, adaptive, and decentralised approaches. If you missed it - you can watch the full recording here: www.youtube.com/watch?v=Dpej...

Join us this evening to celebrate Prof Victoria Cornelius, Director of ICTU. Victoria will be sharing her academic journey through her research looking at examples where innovations in statistical methods have made real changes to clinical trials and the outcomes achieved.

Under pressure: smarter trials for better health outcomes

Join us for Professor Victoria Cornelius' inaugural lecture in person or online.

imperial.ac.uk

📢 New publication in #Trials led by @suziecro.bsky.social with the HEALTHY STATS public involvement group: Supporting public involvement in defining estimands: a practical tool accessibly explaining the five key attributes of an estimand trialsjournal.biomedcentral.com/articles/10....

Supporting public involvement in defining estimands: a practical tool accessibly explaining the five key attributes of an estimand - Trials

Background An estimand is a precise description of the treatment effect a trial is aiming to find out. We previously identified that public partners (defined as patients and/or members of the public w...

trialsjournal.biomedcentral.com

📢 Interested in a PhD in clinical trials methodology? The Trials Methodology Research Partnership are advertising projects for PhDs starting Oct 2026, in statistics, health economics, epidemiology, social science, and more, hosted at one of 12 UK partner institutions. mrctmrpdtp.com/current-oppo...

Current Opportunities

We have an iCASE studentship available to start for the 2025/2026 academic year, and applications to our fifth round of recruitment to our DTP to start in October 2026 are now also open. Please see…

mrctmrpdtp.com

📢 New blog post: www.statsci.co.uk/post/highlig... One of our NIHR pre-doctoral fellows Xiao Xuan Tan recently attended ISCB 2025 which was packed with cutting-edge statistical research & inspiring keynotes. Read all about her key highlights and takeaways from attending the conference here

Highlights and Reflections from ISCB 2025

This summer, I had the opportunity to attend the 46th Annual Conference of the International Society for Clinical Biostatistics (ISCB) in Basel. It was an incredible week of learning and networking wi...

statsci.co.uk

💡 Have you ever taken part in a clinical trial or thought about it? We want to hear your views on how health data is collected using technology like apps, wearable devices, and medical records. 🕐 5 mins, anonymous. imperial.eu.qualtrics.com/jfe/form/SV_... #PPIE #ClinicalTrials #DigitalHealth

New publication 📢: A Bayesian framework to evaluate non-inferiority in randomised controlled trials of uncommon conditions - Journal of Clinical Epidemiology led by @vcornelius.bsky.social www.jclinepi.com/article/S089...

A Bayesian framework to evaluate non-inferiority in randomised controlled trials of uncommon conditions

Non-inferiority (NI) trials typically require larger sample sizes than superiority comparisons. This is problematic for uncommon conditions where recruitment is restricted. When a power calculation re...

jclinepi.com

📢 Chelsea&Westminster Hospital NHS Trust Research Dept. are looking for an enthusiastic & dedicated senior statistician with experience working on drug trials to lead on the statistical work for a small portfolio of sponsored studies. For details please see here: www.chelwest.nhs.uk/about-us/wor...

Yesterday we welcomed the new @imperialcollegeldn.bsky.social MSc Public Health cohort to the ‘Introduction to Statistical Thinking and Data Analysis’ module co-led by @suziecro.bsky.social and @rachpips.bsky.social - building the foundations of statistics for their future public health careers.

💬Got 5 mins? Help improve clinical trials by sharing your thoughts on health data collection. @anniestats.bsky.social a PhD researcher at Imperial has designed this survey with the help of her public involvement groups. 🔗 imperial.eu.qualtrics.com/jfe/form/SV_... #PPI #HealthEquity #ResearchVoices

New publication 📣: Are estimands being correctly used? A review of UK research protocols by Timothy P. Clark, Richard H. Wicentowski, Suzie Cro, Matthew R. Sydes & Brennan C. Kahan trialsjournal.biomedcentral.com/articles/10....

Are estimands being correctly used? A review of UK research protocols - Trials

Background The use of estimands in clinical trials was formalised with the adoption of the final International Conference on Harmonisation E9 Addendum on Estimands and Sensitivity Analysis in Clinical...

trialsjournal.biomedcentral.com

Attending the International Society for Clinical Biostatistics this week? Don’t miss @ellievanvogt.bsky.social and Xiao Xuan who will be presenting these exciting topics:

Meet Alex Dixon, who is spending his summer experiencing life within ICTUs statistics and trial methodology group and conducting a research project with us as part of an NIHR undergraduate internship Find out what he has been up to here: www.statsci.co.uk/news

🔊We're hiring! Imperial Clinical Trials Unit are looking for an ambitious senior statistician with experience in clinical trials & design & analysis of adaptive trials to lead a research programme in antimicrobial resistance & data-enabled trials. Full details: www.imperial.ac.uk/jobs/search-...

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

imperial.ac.uk

Delighted to share registration is open for Professor @vcornelius.bsky.social inaugural lecture -Under pressure: smarter trials for better health outcomes- Thursday, 30 October 2025, 17.30-18.30, Imperial College South Kensington/Online. For details & registration: www.imperial.ac.uk/events/19688...

New publication📣: Incorporation of Patient and Public Involvement in Statistical Methodology Research: Summary of Workshop Proceedings - aimed at addressing barriers to meaningful PPI in statistical methodology research. Open access in Statistics in Medicine onlinelibrary.wiley.com/doi/10.1002/...

The heatwave didn't stop us from dressing up yesterday for the Charlie & the Chocolate Factory theme summer social! Some amazing outfits here, can you guess the characters? #SummerSocial #StatsTeam #Heatwave

Thank you to Yulia Marchenko from StataCorp for sharing some really handy tips for creating programs in Stata, and for the fantastic insight to the suite of Bayes commands! #Stata #Bayesian #Programming

Curious about trust in trials? FREE webinar: 21 July, 3pm UK, exploring what makes research trustworthy. Hosted by @iasp.bsky.social PRF & supported by the @jclinepi.bsky.social 👥 Speakers are leading trust and integrity researchers and journal editors. 💬 Plus live Q&A! shorturl.at/FEeMz

Congratulations to @rachpips.bsky.social on her new role as part of the #UKCTUNetwork Statistics Group!

UK CTU Network@ukctunetwork.org · last yr.

Stephen Bremner & Jo Haviland, joint chairs of the Stats Group, update delegates on recent activities—plus a warm welcome to the group’s new members! Wonderful to see the group continue to attract people with such a wide range of specialties & interests #UKCTUNetwork #TrialStatistics #CTUStats2025

Attending NIHR stats conference this week @nihr.bsky.social? Don’t miss @anniestats.bsky.social , Leila Janani x.com/LeilaJTF, Jack Elkes, Marie Miller, and Francesco Lala, who will be presenting these exciting topics:

Delighted to share our first paper on the NeuOst intervention 😊 I’ve grown very passionate about this integrated physical and psychological approach for people w/ painful diabetic neuropathy. ...Results are coming soon! www.tandfonline.com/doi/full/10....

A multimodal intervention of manual therapy, exercise, and psychological management for painful diabetic neuropathy: intervention development and feasibility trial protocol

Therapeutic options for people experiencing neuropathic pain from diabetic peripheral neuropathy are limited, and impact can be severe. Physical and psychological interventions remain under-explore...

tandfonline.com

You can catch up on all of the Trials Special Series on #AdverseEvent webinars curated by @rachpips.bsky.social and @vcornelius.bsky.social so far on: www.statsci.co.uk/webinar-series

📢 The 11th annual meeting on Current Developments in Cluster Randomised Trials & Stepped Wedge Designs will take place 18/19 November 2025 in Birmingham UK. Abstract submission is open, deadline for submission 11 July 2025 forms.gle/jS83TAKhs4U8.... Info on registration etc to follow!

Attending #PSI2025 at Wembley stadium ⚽ this week? Don’t miss new research on a novel multiple imputation procedure for handling missing data in clinical trials targeting a treatment policy estimand by @suziecro.bsky.social James Roger & James Carpenter