Reported problems and responses during the conduct of stepped-wedge cluster randomized trials in healthcare settings: a qualitative systematic review

AbstractBackground. The stepped-wedge cluster randomized trial (SW-CRT) is a pragmatic complex design that can be difficult to implement. We aimed to summa

academic.oup.com

Role of recruitment bias in stepped-wedge cluster randomised controlled trials: a systematic review

Objectives Increased popularity of stepped-wedge cluster randomised trials (SW-CRT) highlights the importance of understanding and appropriate mitigation of sources of bias within this trial design. W...

bmjopen.bmj.com

A scoping review identified additional considerations for defining estimands in cluster randomised trials

An estimand is a clear description of the treatment effect a study aims to quantify. The ICH E9(R1) addendum lists five attributes that should be described when defining an estimand. However, the adde...

jclinepi.com

CRT Conference 2025 | University of Birmingham Online Shop

The 11th annual meeting on Current Developments in Cluster Randomised Trials & Stepped Wedge Designs

shop.bham.ac.uk

Assessing Mediation in Cross‐Sectional Stepped Wedge Cluster Randomized Trials

Mediation analysis has been studied for independent data, but relatively little work has been done for correlated data observed under stepped wedge cluster randomized trials (SW-CRTs). Motivated by t...

onlinelibrary.wiley.com

Information-Theoretic Criteria for Optimizing Designs of Individually Randomized Stepped-Wedge Clinical Trials - Statistics and Computing

Clinical trials are essential for advancing medical knowledge and improving health care, with Randomized Clinical Trials (RCTs) considered the gold standard for minimizing bias and generating reliable...

link.springer.com

Grand rounds in methodology: improving the design of staggered implementation cluster randomised trials

The stepped-wedge cluster randomised trial is a popular design in implementation and health services research. All clusters, such as clinics or hospitals, start in the control state, and gradually swi...

qualitysafety.bmj.com

Power calculation for cross-sectional stepped wedge cluster randomized trials with a time-to-event endpoint

ABSTRACT. Stepped wedge cluster randomized trials (SW-CRTs) are a form of randomized trial whereby clusters are progressively transitioned from control to

doi.org

Identifying Less Burdensome and More Cost‐Efficient Incomplete Stepped Wedge Designs for Continuous Outcomes Collected via Repeated Cross‐Sections

Stepped wedge trials can be costly and burdensome. Recent work has investigated the iterative removal of cluster-period cells from stepped wedge designs, producing a series of candidate incomplete de...

onlinelibrary.wiley.com

How Should Parallel Cluster Randomized Trials With a Baseline Period be Analyzed?—A Survey of Estimands and Common Estimators

The parallel cluster randomized trial with baseline (PB-CRT) is a common variant of the standard parallel cluster randomized trial (P-CRT). We define two natural estimands in the context of PB-CRTs w....

onlinelibrary.wiley.com

What Is a Stepped-Wedge Cluster Randomized Trial?

This Guide to Statistics and Methods describes design, interpretation, and examples of a stepped-wedge cluster randomized trial.

jamanetwork.com

Bayesian Hierarchical Penalized Spline Models for Immediate and Time‐Varying Intervention Effects in Stepped Wedge Cluster Randomized Trials

Stepped wedge cluster randomized trials (SWCRTs) often face challenges related to potential confounding by time. Traditional frequentist methods may not provide adequate coverage of an intervention's ...

pmc.ncbi.nlm.nih.gov

Analysis of Cohort Stepped Wedge Cluster-Randomized Trials With Nonignorable Dropout via Joint Modeling - PubMed

Stepped wedge cluster-randomized trial (CRTs) designs randomize clusters of individuals to intervention sequences, ensuring that every cluster eventually transitions from a control period to receive t...

pubmed.ncbi.nlm.nih.gov

Sage Journals: Discover world-class research

Subscription and open access journals from Sage, the world's leading independent academic publisher.

journals.sagepub.com

A systematic review of stepped wedge cluster randomized trials in high impact journals: assessing the design, rationale, and analysis

Stepped wedge cluster randomized trials (SW-CRTs) are an appealing study design because they enable sequential roll out of an intervention across clusters, bringing logistical advantages. This review ...

jclinepi.com

How nurse researchers can use stepped-wedge design and analysis

How nurse researchers can use stepped-wedge design and analysis

journals.rcni.com

Multilevel Intervention Stepped Wedge Designs (MLI-SWDs) - Prevention Science

Multilevel interventions (MLIs) hold promise for reducing health inequities by intervening at multiple types of social determinants of health consistent with the socioecological model of health. In sp...

link.springer.com

Reporting of cluster randomised crossover trials: extension of the CONSORT 2010 statement with explanation and elaboration

This article presents the CONSORT (consolidated standards of reporting trials) extension for cluster randomised crossover trials. A cluster randomised crossover trial involves randomisation of groups ...

bmj.com

A Systematic Review of Stepped Wedge Cluster Randomized Trials in High Impact Journals: Assessing the Design, Rationale, and Analysis

Stepped wedge cluster randomized trials (SW-CRTs) are an appealing study design because they enable sequential roll out of an intervention across clusters, bringing logistical advantages. This review ...

jclinepi.com

The application of stepped-wedge cluster-randomized controlled trial study designs in oncology settings: A systematic review

Stepped-wedge cluster-randomized trials (SW-CRTs) offer advantages for implementation research in healthcare and have been increasingly utilised in th…

sciencedirect.com