Today’s potent #cannabis products pose a risk to the mental health of adolescents. To the brave parents turning their pain into advocacy, thank you for all you do at Johnny's Ambassadors & for inviting me to speak at your conference ♥️ Learn more here: johnnysambassadors.org/research/

Congratulations to @jenbussell.bsky.social and the whole team on this work! I'm so happy to see it out in the world 🎉 @ryanpaulbadman1.bsky.social

Jennifer Bussell PhD@jenbussell.bsky.social · 6d ago

How does the brain represent the value of knowledge? In our paper--out now at Nature Neuroscience--we identify a representation of intrinsic information value within neural population structures in the orbitofrontal cortex in mice. www.nature.com/articles/s41593-026-02377-y #neuroskyence 🧠🧪 (1/8)

Heading to #CCN26? Stop by and see what the Rajan Lab has been working on! Don't miss presentations from John Vastola, Satpreet Singh, and Nathan Wu. Drop by their sessions to chat about our ongoing projects and say hello to the team! @purpleantelope.bsky.social @satpreetsingh.bsky.social

Excited to share this paper led by two undergrads in the lab, out now in Neurobiology of Stress! Temporal reorganization of maternal care during early life stress in mice doi.org/10.1016/j.yn...

We're hiring professional track faculty in Psychology at UT Austin! Two Asst/Assoc Professor of Instruction positions & one Clinical Asst/Assoc Professor position for a licensed clinical psychologist. Instruction: apply.interfolio.com/188637 Clinical: apply.interfolio.com/188633 Please share!

Future BCIs could provide treatment for widespread disorders like depression, anxiety, PTSD, and OCD. Thanks to @neurosciencenews.bsky.social for covering the key takeaways and open questions from my recent review on the emerging field of cognitive BCIs. neurosciencenews.com/bci-depressi...

How Closed-Loop BCIs Will Treat Depression, Anxiety, and PTSD - Neuroscience News

A new study outlines closed-loop cognitive BCIs for depression, PTSD, and OCD.

neurosciencenews.com

Meet the team! Today’s spotlight: Erin Scott ✨ Erin is a PhD student working to characterize a family of dopamine sensors for the dLight 3.0 series. She is also developing a sensor for alpha-synuclein, a toxic protein heavily implicated in Parkinson’s disease.

We are hiring a number of AIxBio positions across the organization, including Directors of Machine Learning for each of our Institute Initiatives and postdoctoral fellows focused on ML for Biology and Biological Design in Patrick Hsu's Lab. Learn more or apply here: arcinstitute.org/jobs

Jobs | Arc Institute

Arc Institute is an independent nonprofit research organization headquartered in Palo Alto, California.

arcinstitute.org

What’s holding us back from developing a clinical BCI for mental health? My new review in @cp-trendscognsci.bsky.social outlines a roadmap to overcome the unique hurdles facing cognitive BCIs by integrating & expanding on existing neurotech methods. Read here: authors.elsevier.com/a/1nSLK4sIRv...

Complex I is the largest complex of the electron transport chain and the entry point for electrons that power ATP production. New work from Core Investigator Isha Jain and team identifies THAP12 as a dedicated transcription factor controlling how much Complex I a cell builds.

Behavior-trained AI captures what we do but not the mental process behind it. @patrickmineault.bsky.social & I call that gap cognitive dark matter & think it explains a lot about where today's models could be improved. Enjoyed this chat with Jan Witkowski at CSHL. www.youtube.com/watch?v=s4t6...

Interview with: Sean Escola

YouTube video by CSHL Leading Strand

youtube.com

Looking forward to this webinar! 🤓 Thank you to AFAR and MBRF for hosting it for World Brain Day! Register to watch it here: us02web.zoom.us/webinar/regi...

@mcknightbrain.bsky.social · 4w ago

Less than 2 weeks until our brain health webinar with the American Federation for Aging Research, featuring Leah Acker, MD, PhD, Duke University, Denise Cai, PhD, Icahn School of Medicine at Mount Sinai & Amit Etkin, MD, PhD, Alto Neuroscience. Learn more & RSVP: us02web.zoom.us/.../reg.../W...

Thanks to @bipolardiscoveries.org for supporting our work on the circuit-level basis of bipolar disorder! By uniting neurosurgery, neuroscience, and psychiatry, our unique multidisciplinary team is unlocking vital new insights into how the human brain works. More to come soon!

BD²@bipolardiscoveries.org · 3w ago

🧠 BD² PI @ignaciosaezphd.bsky.social and his team are using deep brain stimulation and epilepsy-based brain recordings to better understand the circuits that drive mood changes in bipolar disorder. The more we learn about these circuits, the closer we get to treatments tailored to brain biology.

Thoughtful insights from Michael Mager of @precisionneuro.bsky.social on what finally made commercial neural interfaces viable, and the potential future impact of BCIs on mental health. Read the interview at Rebellion Research: www.rebellionresearch.com/precision-ne...

Precision Neuroscience Co-Founder & CEO Michael Mager Sits Down With Rebellion Research

Precision Neuroscience Co-Founder & CEO Michael Mager Sits Down With Rebellion Research

rebellionresearch.com

We'll be at @umlaufsculpture.bsky.social Family Day this Sunday! Stop by our table to explore hands-on science activities & learn more about our work. Whether you're a curious kid, a budding scientist, or love learning something new, we want to meet you! Join us for a day of art, nature & STEAM!

Effective treatments for mitochondrial disease are scarce. A new paper in Nature Metabolism from Core Investigator Isha Jain and team offers one, showing that breathing low-oxygen air nearly triples lifespan in a mouse model of HTRA2 deficiency.

AI models are trained on the outputs of human cognition, like behavior, but miss the underlying processes. It was great chatting about this “cognitive dark matter” with Annelies Gamble and how it could be key to improving the cognitive capabilities of AI. www.mixtureofexperts.co/p/the-though...

The thoughts that never become behavior

A conversation with Sean Escola, Dan Wetmore, and Tom Griffiths

mixtureofexperts.co

🤔 Why does prior stress make future stress hit harder? In new work led by @zachtpennington.bsky.social, the Cai Lab discovered a brain circuit that controls stress vulnerability, reshaping how the brain reacts to the next stressor. I'll be speaking about at @fens.org. Come check it out!

We just wrapped our first cycle of Fast Grants: we’re funding 37 projects across diagnostics, AI scientists, phage therapies, and more. Global demand for fast, flexible research funding is even larger than we expected, and it’s shaping how we’re building Cycle 2 this fall. More to come soon.

Big congrats to @rhienhare.bsky.social on her promotion to Account Supervisor this month! ✨

🎉 Congratulations to @zachtpennington.bsky.social on receiving this year's Banting Discovery Award! I worked closely with Zach when he was a postdoc in my lab and I know he is incredibly deserving of this award. Read more about his award here: psych.ubc.ca/news/zachary...

Two milestones in the Preston Lab this week 🎉 1️⃣ Andrei Amatuni defended his dissertation proposal! His work asks how we learn the hidden structure of experience & use it to reason in new situations + how that ability develops from childhood to adulthood. Congrats, Andrei!

Science Fellow Jingtian Zhou and colleagues traced stress-driven glioma growth in mice to a bone marrow-derived macrophage that infiltrates the brain tumor and acts on the immune environment rather than the tumor cells.

As kids break for summer, it’s important to talk with them about #cannabis use. The cannabis products sold today have a high THC content, risking addiction and long-term effects on developing brains 🧠 Empower kids to make the right decisions for a happy and healthy summer ☀️

Nobody spells it out like @kordinglab.bsky.social. In this latest @juanbenetpodcast.bsky.social episode, Konrad discusses why we need “compilers” to translate molecularly annotated connectomes into neural dynamics – generating data we could use to build better AI. www.youtube.com/watch?v=FHQf...

The Power of a Single Neuron and a Path to Simulating the Brain | Dr. Konrad Kording

YouTube video by Juan Benet Podcast

youtube.com

Start assembling your team because the 2026 Virtual Cell Challenge officially kicks off on Thursday, August 20. This is round two of our global competition to understand and predict how cells respond to internal cues and external stimuli.

Cells control gene expression through combinatorial interactions between readers, writers, and erasers of chromatin marks, but most epigenetic editing tools rely on a single effector in isolation. COMBINE is the first platform to test those combinations at scale, screening 50,000+ effector pairs.

Congratulations to PSFC on their new website. Coordinated philanthropy for safe, ethical, evidence-based access to psychedelic healing — visual identity, illustrations, and report design via @stellatecomms.bsky.social. psfc.co | stellatecomms.com/creative-portfolio

Congrats to @brianhie.bsky.social, @synbiogaolab.bsky.social, & team on Germinal, now out in NatBiotech. Their pipeline designs epitope-targeted antibodies with nanomolar affinity while testing only tens of designs per target, making antibody design far more accessible. nature.com/articles/s41...

Efficient generation of epitope-targeted antibodies with Germinal - Nature Biotechnology

Germinal achieves epitope-targeted, de novo complementarity-determining region design with high experimental success rates.

nature.com

Arc Institute@arcinstitute.org · 11mo ago

In another preprint from the @brianhie.bsky.social Lab and @synbiogaolab.bsky.social, they introduce Germinal, a generative AI system for de novo antibody design. Germinal produces functional nanobodies in just dozens of tests, making custom antibody design more accessible than ever before.

Mentorship works best when we stop expecting one person to do all the mentoring. We talk about needing "a mentor," singular. But a better model is constellation mentoring: a set of relationships that together give us what we need, shifting as we do. We all need a constellation!