Researchers from the National University of Singapore recently discussed how they identified a new developmental mechanism that contributes to the absence of the nose using stem cell models. Listen to the latest episode of The Stem Cell Report podcast to learn more: https://ow.ly/X7gg50ZfXIw
Stem Cell Reports
@stemcellreports.bsky.social
For scientists. By scientists. The official journal of the @isscr.org | Editor-in-Chief: Janet Rossant, CC, PhD
Listen to the latest episode of The Stem Cell Report podcast to hear how researchers from the National University of Singapore are addressing human craniofacial development using stem cell models 👉 https://ow.ly/5FQ950ZfXzY
👏 Thank you, Martin Pera, for your transformative leadership of Stem Cell Reports. From launching The Stem Cell Report podcast to creating the Early Career Editorial Board & advancing research rigor, Martin helped shape the journal & elevate voices across the community. https://ow.ly/Ng8l50Z7G4O
The ISSCR Celebrates Martin Pera for Transformative Leadership and Lasting Contributions to Stem Cell Reports as he Steps Down from the Journal’s Editorial Team — International Society for Stem Cell Research
The International Society for Stem Cell Research (ISSCR) and Stem Cell Reports are celebrating the remarkable contributions of Martin Pera as he concludes his long tenure with the journal following years of leadership that helped shape Stem Cell Reports into a leading voice in stem cell science
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Check out the paper in @stemcellreports.bsky.social www.cell.com/stem-cell-re... A collaborative effort between researchers at @fraunhoferitmp.bsky.social, @eu-openscreen.bsky.social, @mdc-berlin.bsky.social, and @hhu.de
Human organoids: Fit for drug discovery?
Wittich et al. provide an overview of human PSC-derived organoid screening technologies and outline key considerations for integrating them into drug discovery pipelines. As new approach methodologies...
cell.com
I’m delighted to serve as an Early Career Editor for @stemcellreports.bsky.social, the society journal of @isscr.org. Stem Cell Reports welcomes rigorous work across the stem cell field, from basic mechanisms to emerging applications. Consider us for your next submission! invt.io/1bxb03y6b81
Check out ISSCR's society journal, Stem Cell Reports!
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🎉 Welcome to the newest Early Career Editors of Stem Cell Reports! Their global perspectives will help shape the future of stem cell science and publishing. 🌍Read more: https://ow.ly/Sji850Z7FmI Alessandro Bertero, Shifeng Xue,
Guests on the latest episode of The Stem Cell Report shared reports from Health Canada–regulated Phase I and Phase II trials evaluating freshly cultured umbilical cord–derived MSCs in patients with COVID-19-related ARDS. https://ow.ly/Cnr750Z2u4n
From basic discovery to clinical translation, @ISSCR_org's open-access society journal showcases research shaping the field. @stemcellreports.bsky.social is the Official Meeting Journal of #ISSCR2026. Learn more about the journal and meet the editorial team this July! invt.io/1bxbkyomhe6
Stem Cell Reports, the ISSCR 2026 Official Meeting Journal.
Learn more.
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In the latest episode of The Stem Cell Report, guest share how their work explores a therapeutic strategy to improve ARDS outcomes using MSCs, which will be important for optimizing and targeting future cellular therapies. Listen to the full episode 👉https://ow.ly/Iytp50Z2sa9
New podcast episode! Guests from The Ottawa Hospital report results from a Health Canada-regulated Phase I and Phase II trials evaluating freshly cultured umbilical cord-derived MSCs in patients with COVID-19-related ARDS. Listen now 👉https://ow.ly/F7e650Z2rZK
Stem Cell Reports is proud to be the official meeting journal of BaCell 3D, taking place 22-24 June, 2026 in Basel, Switzerland. https://www.isscr.org/unaffiliated-events/bacell3d
Online now! Mitochondrial toxins cause widespread downregulation of pathways in X-linked dystonia-parkinsonism patient-derived neurons. https://ow.ly/4WPA50YXPf8
Are human organoids fit for drug discovery? New review explores screening strategies, ML-enabled readouts, and advantages over traditional models, while addressing major challenges like scalability, robustness, throughput, and standardization needed for pharma adoption. https://ow.ly/nBPJ50YXP6z
Online Now! NRG-1 restoration reactivates NPCs and fosters hippocampal repair by supporting neurogenesis, neuronal complexity, synaptogenesis, and remyelination that reverses memory loss in mice with progressive brain demyelination👉 https://bit.ly/4t9sB6K
Stem Cell Reports, ISSCR's open-access, peer-reviewed journal, has been named the Official Conference Journal of the BaCell3D Organoid Conference, taking place 22-24 June 2026 in Basel, Switzerland. Read more 👉 https://ow.ly/Bo7Q50YRJff
Online now in Stem Cell Reports! TOE1 is a β-catenin interacting protein and novel regulator of hematopoietic cell proliferation through PAK2 modulation https://ow.ly/297I50YP49O ISSCR | Cell Press The Gairdner Foundation | SickKids Foundation
Check out this new #organoid research in Stem Cell Reports: MECP2 mutations rewire human embryonic stem cell fate and bias cortical lineage commitment https://ow.ly/N37850YP3V3 ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
New paper provides ultrastructural and 3-D features of ventricular-subventricular zone (V-SVZ) neuroblasts in postnatal microminipigs, establishing them as a tractable gyrencephalic model for postnatal neurogenesis. https://ow.ly/gRnc50YKv4L ISSCR | The Gairdner Foundation | SickKids Foundation
Online Now! An optimized protocol for efficient derivation of pancreatic islets from multiple human pluripotent stem cell lines that enables production of highly functional stem cell-islets suitable for type 1 diabetes cell therapy. https://ow.ly/RUML50YKuVP ISSCR | Cell Press
In this anniversary episode, Janet Rossant is joined by a few of our past guests who helped define the conversations of the past five years. Revisit where their work stood then, explore where it has gone since, & take a closer look at what lies ahead 👉https://ow.ly/WcRv50YJ0Uo
Check out this new intestinal #organoid research: Phenotypic screening identified that glycyrrhizin confers protection against tumor necrosis factor-induced cell death, which may be a novel therapeutic compound for Crohn’s disease. https://ow.ly/VZvQ50YKuMG
New #RareDisease research! Bosma arrhinia microphthalmia syndrome (BAMS) is marked by the absence of a nose and eye/reproductive anomalies, which may result from impaired differentiation to cranial placode cells and changes in cell adhesion. https://ow.ly/kRPX50YGFGl
Stem Cell Reports, ISSCR's open-access, peer-reviewed journal, has been named the Official Conference Journal of the BaCell3D Organoid Conference, taking place 22-24 June 2026 in Basel, Switzerland. Read more 👉 https://ow.ly/mesl50YInK1
Chemotherapy-induced thrombocytopenia (CIT) is a severe complication in elderly cancer patients. New research shows that dietary restriction mitigates CIT in aged mice via mitochondrial potentiation in hematopoietic stem cells and megakaryocyte progenitors. https://ow.ly/VpFm50YEMX5
A nuclear receptor screen identifies Rora as a dose-dependent regulator of cell fate. Transcription factor dosage—not just identity—drives reprogramming efficiency, pointing to nuclear receptor modulation as a lever for cell plasticity https://ow.ly/B4jU50YEN1g
A screen of 49 nuclear receptors identifies the ROR subfamily as OKS (OCT4/KLF4/SOX2) enhancers. Rora acts as a dose-dependent regulator of cell fate, tuning reprogramming efficiency. https://ow.ly/XPlQ50YEMWN Cell Press | The Gairdner Foundation | SickKids Foundation
Stem Cell Reports is pleased to announce the appointment of Hongmei Wang, Ph.D., as an Associate Editor. Dr. Wang is a professor of State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology (IOZ), Chinese Academy of Sciences (CAS). Read more 👉https://ow.ly/rfEu50YGw9E
New research from Duke University in Stem Cell Reports uses multimodal human podocyte injury models to discover kidney disease targets, highlighting the predictive power of human-relevant experimental models. https://ow.ly/5gsa50YEMWk Cell Press | The Gairdner Foundation | SickKids Foundation
Online Now! A semi-automated multi-electrode arrays (MEA) spike sorting method for high-throughput assessment of cultured neurons; enhances the resolution & utility of MEA in disease modeling and drug development using hPSC-derived neurons. https://ow.ly/lzkW50YEMVV
Stem Cell Reports is proud to be the official meeting journal for the 20th Annual Wisconsin Stem Cell Symposium! Learn more about the event 👉 https://stemcells.wisc.edu/7376-2/