And it's finally out!!! www.nature.com/articles/s41... go.nature.com/4fuaJzW Congrats to first author @moisesdisante and the research teams in my Synthetic Physiology Lab @unipv.bsky.social @berterolab.bsky.social and @florianjug.bsky.social .

#CALIPERSv2 🚀 preprint is locked—journal submission next. Final polish, more hiPSC reference lines, and fresh light-sheet data. Still, a great collaboration led by @moisesdisante with the team @LabPhysiology and the amazing @berterolab.bsky.social and @florianjug.bsky.social group members! 1/N

Eager to share our pre-printed #CIRI platform during this upcoming FREE webminar organized by @10xgenomics.bsky.social

10x Genomics@10xgenomics.bsky.social · 3w ago

Join us on Tuesday, July 21, for a webinar on combinatorial CRISPR screens in human iPSCs. Explore how pooled single cell screening and TF mapping enable predictive modeling of cell fate. Register at https://bit.ly/4pFBUeB

In this ISSCR Member Spotlight, Alessandro Bertero reflects on his group's work on how chromatin architecture guides pluripotent stem cell differentiation, the importance of international collaboration, and the experiences that have shaped his career. Read more: https://bit.ly/4uCsOQE

🎉 Welcome to the newest Early Career Editors of Stem Cell Reports! Their global perspectives will help shape the future of stem cell science and publishing. 🌍Read more: https://ow.ly/Sji850Z7FmI Alessandro Bertero, Shifeng Xue,

I’m delighted to serve as an Early Career Editor for @stemcellreports.bsky.social, the society journal of @isscr.org. Stem Cell Reports welcomes rigorous work across the stem cell field, from basic mechanisms to emerging applications. Consider us for your next submission! invt.io/1bxb03y6b81

Check out ISSCR's society journal, Stem Cell Reports!

invt.io

Este jueves, en el IBBTEC: > CHROMATIN ARCHITECTING: UNDERSTANDING AND PROGRAMMING STEM CELL DIFERENTIATION. Con Alessandro Bertero, investigador invitado de la Universidad de Turín. IBBTEC (PCTCAN - Cantabria) - 13 h. #ibbtec @berterolab.bsky.social #BerteroLab #seminar

Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇

New paper in @natcomms.nature.com: we report #TwinC, a neural network model that predicts inter-chromosomal genome architecture from sequence only. Great collaboration with Bill Noble’s group at UW led by @anupamajha.bsky.social. Thanks to @erc.europa.eu for support! www.nature.com/articles/s41...

Applications open for the Stem Cell & Developmental Biology Early Career Symposium being held September 23-25, 2026 in Seattle, WA. This joint symposium is a collaboration between @alleninstitute.org, @isscr.org and @socdevbio.bsky.social Application Deadline: May 1. bit.ly/4p98dkv

Applications are now open for the Stem Cell & Development Biology Early Career Symposium! Together with @isscr.org and @socdevbio.bsky.social, we're hosting a scientific focused on incubating the next generation of research leaders. Apply by May 1 at: https://bit.ly/4lriiZm

Excited to see our work on the cover of @molsystbiol.org! Cover art by Laura Seclì shows barcoded #stemcell clones navigating inducible perturbations: iPS2-seq reads each trajectory, and catcheR sorts clones—highlighting SMAD2 as a key #cardiac regulator and capturing epigenetically biased outliers.

Molecular Systems Biology@molsystbiol.org · 6mo ago

2/2026 Issue ➡️ link.springer.com/journal/4432... expansion microscopy, spatial omics and gene networks, cell population control by cell cycle, #IBD heterogeneity, aging monkey lipid signatures Cover: single-cell loss-of-function screening in human pluripotent stem cells from @berterolab.bsky.social

iPS2-seq is a clone-aware platform for #singlecell loss-of-function screening in #hiPSCs and derivatives including #organoids, here revealing SMAD2 role in cardiac progenitor specification from @berterolab.bsky.social @mendjanlab.bsky.social #functionalgenomics ➡️ link.springer.com/article/10.1...

💸 Stem cell culture that’s ~95% cheaper and weekend-free: a win-win for PIs and trainees! Our revised manuscript is online at ORE: open-research-europe.ec.europa.eu/articles/4-1... Benchmarked across cell lines & differentiation protocols, including scRNA-seq — with lessons for #cultivatedmeat too!

A tour de force that elevates the #CALIPERS technology to a whole new level! A must read for all iPSCs, cell cycle, and developmental biology aficionados.

#CALIPERSv2 🚀 preprint is locked—journal submission next. Final polish, more hiPSC reference lines, and fresh light-sheet data. Still, a great collaboration led by @moisesdisante with the team @LabPhysiology and the amazing @berterolab.bsky.social and @florianjug.bsky.social group members! 1/N

#CALIPERSv2 🚀 preprint is locked—journal submission next. Final polish, more hiPSC reference lines, and fresh light-sheet data. Still, a great collaboration led by @moisesdisante with the team @LabPhysiology and the amazing @berterolab.bsky.social and @florianjug.bsky.social group members! 1/N

This is the way forward: here’s hope the “Fondo Italiano per la Scienza” will embrace this model instead of performing long, expensive, and less rigorous new evaluations (plus asking scientists to rewrite in ~half the space an already dense project)

European Research Council (ERC)@erc.europa.eu · last yr.

We lack the budget to fund all the project proposals that are assessed as excellent by our peer review panels. So it's encouraging to see that some of these projects eventually receive funding. A big thank you to the Latvian government for supporting excellent science; a worthwhile investment!

This is such an important article, about the simplistic visions now pushing aside scientific research and complex social issues. A must read. newrepublic.com/article/1933...

The Flawed Ideology That Unites Grass-Fed Beef Fans and Anti-Vaxxers

From RFK Jr. to Hollywood A-listers and Democratic senators, people across the political spectrum are jumping onto the slippery slope of nature-based solutionism.

newrepublic.com

Yup. What an effective way to speed up the sixth mass extinction

Dr. Jonathan Foley@globalecoguy.bsky.social · last yr.

The beef industry has done an incredible job of greenwashing -- far better than the fossil fuel industry. And the playbook is pretty damn clear. And, sadly, it's working incredibly well -- to the point of misleading the whole world, including many environmentalists... www.vox.com/future-perfe...

NIH has rescinded its scientific integrity policy. Hard to see this as anything other than clearing the way for shoddy research on things like vaccines. Regardless of the rationale, it's bad news for public health. grants.nih.gov/grants/guide...

Blood chilling list. The nightmare continues

Carl T. Bergstrom@carlbergstrom.com · last yr.

Take the time to follow the link and read for yourself the list of cancelled grants. The combination of cruelty, shortsightedness, and absolute ignorance is astounding.

Honored to be recognized as a 2025 @isscr.org Public Service Award Honoree for my commitment to the Early Career Advisory Committee! Supporting early-career scientists has been a rewarding journey I am very proud of. Read more about the award and my fellow honorees: invt.io/1lxbo0wcokz

#ISSCR joined hundreds of biomedical research organizations to urge House and Senate appropriators to support robust funding for NIH & avoid drastic measures that will slow scientific progress and weaken the U.S. research ecosystem. www.isscr.org/isscr-news/t...

The ISSCR Signs on to Coalition Letter in Support of NIH — International Society for Stem Cell Research

The ISSCR joined with Research!America, hundreds of biomedical research organizations, and thousands of private citizens from the U.S. scientific community to urge House and Senate appropriators to av...

isscr.org

🚀 The first 2025 Call for Access for our National Facilities is now open! Researchers can apply for cutting-edge services in the fields of omics, imaging and data analysis. Submit your proposal by 31 May! Apply here 👉 humantechnopole.it/en/national-...

National Facilities - Human Technopole

humantechnopole.it

Struggling with #silencing of doxycycline-inducible transgenes in human pluripotent #stemcell derived lineages? You're not alone! In my very first #skeetorial I break down our latest paper on potential solutions to this common problem. Read on! 1/10 open-research-europe.ec.europa.eu/articles/4-2...

Superb review from my friends and colleagues in @porpolab.bsky.social that helped me finally grasp the complexity of this often-overlooked disease in cancer patients. Bookmark it and give the authors a follow!

Paolo E Porporato@porpolab.bsky.social · 2y ago

Let's Start this 2025 (and this new Social) with a Post :) Our review on inter-organ crosstalk driving Cancer Cachexia is now available @cp-trendsendomet.bsky.social Systemic metabolic crosstalk as a driver of cancer cachexia by Wyart et al. #Research #CancerCachexia #Metabolism #Muscle

Brilliant work from @grazianomartello.bsky.social, tackling a major shift in the stem cell field to unlock large-scale experimentation with naïve human pluripotent stem cells. Great to see so many friends on the author list—science truly takes a village!

Graziano Martello@grazianomartello.bsky.social · 2y ago

With pleasure we share our preprint reporting robust and cost-effective expansion of naive human Pluripotent Stem Cells without feeder cells. A fantastic collaborative effort with @leeboratory.bsky.social @jzylicz.bsky.social @pasquelab.bsky.social and Nicolas Rivron. tinyurl.com/5n6z9rt9

Seeing is believing! My friends and colleagues in Pavia have delivered a tour de force, packed with stunning images. @fspasqualini.bsky.social is reshaping how I see biology—his preprints might just change your perspective too!

CALIPERS: Cell cycle-Aware Live Imaging for Phenotyping Experiments and Regeneration Studies* led by @moisesdisante and in collaboration with the amazing labs of Ale Bertero and @florianjug.bsky.social www.biorxiv.org/content/10.1...

Hello @bsky.app! Excited to join this island of science escapism in a world going madder each day. We’re the Armenise-Harvard Lab of Genome Architecting at the University of Torino, Italy, applying #stemcell, #CRISPR, #genomics, and #imaging to explore heart #development, #regeneration, and #cellag.