Product Citation⭐ A study from the Université de Montréal used StressMarq's Blood Urea Nitrogen Kit (SKT-213) to examine Peptidylarginine Deiminase 4 as a potential therapeutic agent for systemic lupus erythematosus (SLE). Kit🧪 https://bit.ly/4dVDnZM Paper📖https://bit.ly/4nKXCNh

Blood Urea Nitrogen Kit | BUN Assay | SKT-213

Measure BUN in serum, plasma, or urine. Fast, accurate colorimetric detection for renal studies.

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⭐ New Products! StressMarq now offers Alpha Synuclein E83Q Mutant Monomers and Pre-formed Fibrils (SPR-538 & SPR-539). This rare missense variant promotes accelerated alpha synuclein aggregation, providing a valuable tool for synucleinopathy research. 🧪 Learn more: https://bit.ly/3TA3vSz

Product Citation💡A study out of the Rush University Medical Center used StressMarq's ENaC antibodies (SPC-403, SPC-404, & SPC-405) to investigate the role of CCD-secreted PCSK9 in MCD-associated hypercholesterolemia. Products📘https://bit.ly/4uXyQf2 Paper📖https://bit.ly/4nJGXcS

Product Citation💡A study from the Nagasaki University Graduate School of Biomedical Sciences used StressMarq's HO-1 Antibody (SPC-112) and found that GTS-21 administration attenuated allergic airway inflammation. Antibody📘https://bit.ly/4wOQi7s Paper📖https://bit.ly/4nFmlCm

Anti-HO-1 Antibody (SPC-112) - Rabbit Polyclonal

Order Rabbit Anti-Human HO-1 Polyclonal (SPC-112) from StressMarq. Suitable for WB, ICC/IF, IHC. High-quality antibodies for scientific research.

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Product Citation✨ Researchers at the Okayama University of Science used StressMarq's Tau-441 (2N4R) P301S Mutant PFFs (SPR-329) to show that CAC-717 water can break down pre-aggregated human mutant tau. Tau PFFs💡https://bit.ly/4nENq8M Paper🔬https://bit.ly/4f1bRLo

Human Tau-441 (2N4R) P301S Mutant PFFs (SPR-329)

Order Human Tau-441 (2N4R) P301S Mutant PFFs (SPR-329) from StressMarq. High-quality reagents for neurodegenerative disease research.

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⭐ New Products! StressMarq now offers Alpha Synuclein E83Q Mutant Monomers and Pre-formed Fibrils (SPR-538 & SPR-539). This rare missense variant promotes accelerated alpha synuclein aggregation, providing a valuable tool for synucleinopathy research. 🧪 Learn more: https://bit.ly/3TA3vSz

Product Citation🌟 A study from North Sichuan Medical College used StressMarq's 4-Hydroxynonenal Antibody (SMC-511) to examine how a ketogenic diet impacts cerebral energy metabolism in Alzheimer's disease. Antibody🔎https://bit.ly/3PDCoEi Paper🔬https://bit.ly/4a1iUAe

Anti-4-Hydroxynonenal Antibody - Mouse Monoclonal [12F7]

Order Mouse Anti-4-Hydroxynonenal (4-HNE) Monoclonal IgG1 from StressMarq. Suitable for WB, ICC/IF, ELISA. High-quality antibodies for scientific research.

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🧠 On #WorldAlzheimersDay, take a look at our latest blog: "Alzheimer's Disease: Discovery to Treatment." Explore the key scientific milestones that have shaped our understanding of Alzheimer's disease and the advances driving the development of new treatments. 🔗 Read more: https://bit.ly/3SRRyHN

Alzheimer’s Disease: From Discovery to Treatment

Explore Alzheimer's disease from its 1906 discovery to today's diagnostics, biomarkers, and emerging treatments shaping research and care.

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⭐ New Products! StressMarq now offers Alpha Synuclein E83Q Mutant Monomers and Pre-formed Fibrils (SPR-538 & SPR-539). This rare missense variant promotes accelerated alpha synuclein aggregation, providing a valuable tool for synucleinopathy research. 🧪 Learn more: https://bit.ly/3TA3vSz

Using human brain microvascular endothelial cells (HBMECs), scientists have demonstrated that #tau #oligomers can trigger endothelial barrier dysfunction through activation of the NLRP3 inflammasome pathway. Read more about the experimental findings on the StressMarq Blog 🍏 https://bit.ly/46K77Ev

Tau Oligomers as Key Drivers of Neuroinflammation

Tau oligomers trigger inflammatory signals in brain endothelial cells & increase barrier permeability, contributing to neurovascular dysfunction in Alzheimer's.

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Product Citation: Researchers investigated aldehyde dehydrogenase-2 (ALDH2) as a modulator of acrolein-mediated damage in spinal cord injury, using a transgenic mouse model & StressMarq's #Acrolein Antibody. Paper 💭 https://bit.ly/3SXYDmy Product ☀️ https://bit.ly/3OreOXF

Anti-Acrolein Antibody [2H2] MOLECULAR SIGNATURE®

Acrolein Antibody - Mouse monoclonal antibody to Acrolein conjugated protein, 2H2. Species Independent. Validated for Western Blot, ICC/IF, and ELISA.

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Our team recently enjoyed a fantastic Summer BBQ at Elk Lake! ☀️🌲 As summer winds down, it was a great opportunity to celebrate with the StressMarq team, enjoy delicious food, take part in fun activities, and share plenty of laughs. Thank you to everyone who helped make the day such a success!

Product Citation: StressMarq's #Tau-441 P301S Mutant PFFs played a role in elucidating the relationship between #neurodegeneration & #circadian rhythym dysfunction, in a PS19 mouse model of #tauopathy. 🐭🔬 Paper 📬 https://bit.ly/3HH1Jcd Product 📦 https://bit.ly/3RdB0pI

A novel study conducted by the University of Michigan employed quantitative FACS methods, magnetic-activated sorting, and quantum dots to sort nanobody libraries against fibrillar #tau aggregates found in #neurodegenerative diseases. Read the blog! 💫 https://bit.ly/3ZC62LV

Conformational Nanobodies Targeting Tau Aggregates

The study employs quantitative FACS methods, magnetic-activated sorting, and quantum dots to sort nanobody libraries against fibrillar tau aggregates.

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Product Citation: StressMarq's #Tau dGAE Monomers were employed to demonstrate that antibodies targeting the MTBR/R' region of tau may prevent & even reverse synaptic dysfunction in #Alzheimer's disease. Paper🪐https://bit.ly/4jDmmD8 Product 🚀 https://bit.ly/3ZTh1R4

Truncated Tau(AA297-391) (dGAE) Monomers (SPR-444)

Human Truncated Tau (AA297-391) (dGAE) Protein Monomer expressed in E. coli. Can be used in Alzheimer's and Parkinson's disease research.

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Product Citation: IHM nanoparticles reprogram diseased microglia to degrade αSyn & reduce #neuroinflammation in #Parkinson's disease. StressMarq's Mouse #AlphaSynuclein PFFs were used to model immune crosstalk. Paper 🌱 https://bit.ly/3HIG1nU Product 🍃 https://bit.ly/2HJyYee

Using StressMarq's #BetaSynuclein, #GammaSynuclein & #AmyloidBeta 1-42 PFFs, scientists developed a quiescent seed amplification assay (QSAA) to detect #AlphaSynuclein aggregates in #cerebrospinal fluid & #skin samples. Read about it on the blog! https://bit.ly/43QvnTN

Optimizing Alpha Synuclein Seed Amplification Assays

Seed amplification assays detect abnormal forms of alpha synuclein. An improved quiescent SAA method streamlines this process and maintains tissue integrity.

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Product Citation ⏰ Nitrated #AlphaSynuclein may be a key driver of #PD pathology. A nitration-selective antibody reduced #αSyn spreading & aggregation in Parkinson's disease models seeded with StressMarq's αSyn PFFs & Monomers. Paper 🔖 https://bit.ly/4c7JKYw αSyn 📭 https://bit.ly/2u9YHV2

A recent multi-institution collaboration used O-PTIR spectroscopy to reveal how alpha synuclein and tau cross-seeding creates unique amyloid strains in #neurodegenerative disease. Read the blog🔍 https://bit.ly/4cvRIek

Product Citation🧪 Researchers from the @gladstoneinst.bsky.social used StressMarq's Tau (pSer202/pThr205) antibody (SMC-601) to explore overall tau reduction as a therapeutic strategy for #Alzheimer's disease. Ab🔬 https://bit.ly/3THW8Zd Paper🔍 https://bit.ly/4hMgJWj

Tau Antibody (pSer202/ pThr205) - Rabbit Monoclonal [AH36]

Order Rabbit Anti-Human Tau (pSer202/ pThr205) Monoclonal IgG (SMC-601) from StressMarq. Suitable for WB, DB, ICC/IF, ELISA, IHC. High-quality antibodies for scientific research.

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Product Citation 🔮 StressMarq's #Tau (K18) P301L PFFs & Monomers (SPR-330 & SPR-328) enabled the validation of Leucettine L41 as a modulator of #tau fibril formation, Ser202/Thr205 phosphorylation & pro-inflammatory #cytokine levels. Paper ⭐ https://bit.ly/4wxQpCO Tau 🪄 https://bit.ly/4gvoy1g

Product Citation ☁️ In HuMiNAX, a humanized iPSC-based model of #neurodegeneration, StressMarq’s #Tau (K18) P301L PFFs (SPR-330) induced tau aggregation, neuronal loss & inflammatory #microglial activation. Paper ☀️ https://bit.ly/4x0wddM Tau PFFs 🌈 https://bit.ly/2mMPiSr

Product Citation 🌿 #AlphaSynuclein pathology differentially impacts #dopaminergic neuron subtypes in rodent models of Parkinson's disease seeded with StressMarq's αSyn PFFs & Monomers (SPR-322 & SPR-321). Paper 📫 https://bit.ly/4w6reH9 αSyn 🔖 https://bit.ly/3KcMdGq #PD #neurodegeneration

💡 StressMarq is pleased to be exhibiting in partnership with Neobioscience at the ICNS Conference in Nanjing, China, from August 13-14! Explore StressMarq’s tools for #neuroscience research, including PFFs, Oligomers, Monomers, Antibodies, and more! 🍁 https://bit.ly/2II2Jeg

Product Citation⭐ A study from The Catholic University of Korea used StressMarq's NCC antibody (SPC-402) to test the efficacy of CRISPR/Cas9 gene editing as a potential treatment of Gitelman's syndrome. Antibody📖https://bit.ly/4zhKMve Paper📚https://bit.ly/4z9cw52

Anti-NCC Antibody (SPC-402) - Rabbit Polyclonal

Order Rabbit Anti-Rat NCC Polyclonal (SPC-402) from StressMarq. Suitable for WB, IHC, ICC/IF, IEM. High-quality antibodies for scientific research.

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Product Citation💫 A study from @usask.ca used StressMarq's HSP70/HSC70 antibody (SMC-104) & HSP90 (total) antibody (SMC-149) to research the physiological process of pregnancy recognition in mares. HSP70 Ab https://bit.ly/4g4Vah3 | HSP90 Ab https://bit.ly/4fQLoQN Paper📚https://bit.ly/4qdT57h

Anti-HSP70/HSC70 Antibody - Mouse Monoclonal [N27F3-4]

Order Mouse Anti-Human HSP70/HSC70 Monoclonal IgG1 from StressMarq. Suitable for WB, IHC, ICC/IF, IP, FCM, IEM. High-quality antibodies for scientific research.

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Product Citation🔍 Researchers from Ohio State University used StressMarq's Tau (pSer202/pThr205) antibody (SMC-201) to develop a framework for single-cell resolution spatial transcriptomics in post-mortem brains. Antibody🧪https://bit.ly/3THW8Zd Paper🧫https://bit.ly/4fT5kCF

Tau Antibody (pSer202/ pThr205) - Rabbit Monoclonal [AH36]

Order Rabbit Anti-Human Tau (pSer202/ pThr205) Monoclonal IgG (SMC-601) from StressMarq. Suitable for WB, DB, ICC/IF, ELISA, IHC. High-quality antibodies for scientific research.

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Product Citation⚡ A study from Fukuoka University used StressMarq's KDEL Receptor antibody (SMC-129) to investigate the mechanisms of inhibition of cancer cell line proliferation by the carboline derivative PMC. Antibody⭐ https://bit.ly/4q6XfgU Paper💫 https://bit.ly/4quXFhD

Anti-KDEL Receptor Antibody - Mouse Monoclonal [KR-10]

Order Mouse Anti-Bovine KDEL Receptor Monoclonal IgG1 from StressMarq. Suitable for WB, IHC, ICC/IF, IP. High-quality antibodies for scientific research.

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💫 #Neurodegeneration begins long before the onset of Parkinson's disease symptoms. Explore the cellular mechanisms behind early #PD, including the roles of #neuroinflammation and toxic #AlphaSynuclein #oligomers in disease progression. Read the blog 🔎 https://bit.ly/4gppBQg

Cellular Mechanisms in Early Parkinson’s Disease

Microglial activation and alpha synuclein oligomers drive early Parkinson’s pathology in cortical regions before the formation of Lewy bodies and neuronal loss.

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📢 We’re thrilled to announce that StressMarq has been awarded the EcoVadis Committed Badge! 🌱 This achievement highlights our ongoing commitment to continuous improvement and our dedication to advancing our #environmental, #social, and #ethical practices. Learn more 🌿 https://bit.ly/3WqdGbv