New work from the lab is up on bioRxiv, where we introduce “SpikeLab: Agentic tools for spike data analysis” was led by postdoc Tjitse van der Molen and supported the crew at @ucscgenomics.bsky.social and @baskinengineering.bsky.social www.biorxiv.org/content/10.6...
Sequences are everywhere! In every brain region. And are written in stone. Invariant Activity Sequences Across the Mouse Brain. Out today, by Célian Bimbard, with @kenneth-harris.bsky.social. Based on data by Célian and by @intlbrainlab.bsky.social. www.biorxiv.org/content/10.6...
New research led by #BaskinEngineering Prof @talsharf.bsky.social suggests the brain might be preloaded with a kind of internal template for reading the world, even before the world reaches us - via @discovermag.bsky.social bit.ly/4rFJMx8
Our Brains May Have Pre-Configured Instructions to Understand the World When We're Born
Discover how brain organoids are helping us uncover whether early thought patterns emerge from experience or are hardwired into our DNA.
bit.ly
Slate status: not blank
Auditory-Visual Speech Association (AVISA)@avsp.bsky.social · 8mo agoPreconfigured neuronal firing sequences in human brain organoids www.nature.com/articles/s41... "...results suggest that temporal sequences do not arise in an experience-dependent manner, but are rather constrained by a preconfigured architecture established during neurodevelopment"
I was told it would take about three years to get a new lab up and running. Nearly three years later, our work on preconfigured neuronal firing sequences in human brain organoids is finally out in Nature Neuroscience: www.nature.com/articles/s41...
Preconfigured neuronal firing sequences in human brain organoids - Nature Neuroscience
Examining human brain organoids and ex vivo neonatal murine cortical slices demonstrates that structured neuronal sequences emerge independently of sensory input, highlighting the potential of brain o...
nature.com
"We can, should, and will use cerebral organoids to discover new medical treatments, study brain development, reduce the demand for animal testing, and even power computers and more energy-efficient AI." www.vox.com/future-perfe...
The challenge of creating brains in a lab
Lab-grown brains don’t have to inspire horror.
vox.com
In an NSF-supported study, @talsharf.bsky.social and collaborators will investigate the capacity of human brain organoids to learn and adapt, with implications for #organoid research, #bioethics, and science education. news.ucsc.edu/2025/10/lear...
Effort aims to uncover the learning and reasoning potential of brain organoids
The Braingeneers team will to test the ability of brain organoids to solve tasks in real time
news.ucsc.edu
What if… spontaneous neural activity 🧠 reflects the baseline rumblings of a brainwide dynamical system initialized for learning? We find that the rumblings have macroscopic properties like those emerging from linear symmetric, critical systems 🧵 #neuroscience #neuroAI www.biorxiv.org/content/10.1...
Awesome work by @mrbadash.bsky.social and the crew at @ucscgenomics.bsky.social Goal-directed learning in cortical #organoids www.biorxiv.org/content/10.1...
Goal-Directed Learning in Cortical Organoids
Experimental neuroscience techniques are advancing rapidly, with major recent developments in high-density electrophysiology and targeted electrical stimulation. In combination with these techniques, ...
biorxiv.org
I’m thrilled to share our revised work on neuronal sequences in brain #organoids. It has been an absolute joy to collaborate with an incredible team of talented experimental and computational neuroscientists brought together by this project. www.biorxiv.org/content/10.1...
Protosequences in brain organoids model intrinsic brain states
Neuronal firing sequences are thought to be the basic building blocks of neural coding and information broadcasting within the brain. However, when sequences emerge during neurodevelopment remains unk...
biorxiv.org
