Harnessing the murine inner cell mass mechanical environment enhances derivation of in vitro nascent primitive endoderm precursor cells Read this Article from our special issue #DevSIextracellular by Elena Corujo-Simon, Jennifer Nichols, @kevinchalut.bsky.social & co. doi.org/10.1242/dev....
Takuya Azami
@tazami.bsky.social
Developmental biologist at MRC Human Genetics Unit, Institute of Genetics and Cancer, The University of Edinburgh.
Save the date! The 2027 BSDB Spring Meeting will take place on 19 - 22 April in Edinburgh. An exciting programme with a fantastic lineup of speakers showcasing developmental biology across scales! More details soon!
Another nice visit to Tokyo and a great catch-up with a colleague.
Thank you so much for hosting me! It was a very nice visit!
Today’s speaker in our DRN external seminar series is Dr Takuya Azami (University of Edinburgh) @tazami.bsky.social Host: Anestis Tsakiridis @tsakiridis.bsky.social All welcome!
1/10🧵 New preprint! 🚀 We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place. 👉doi.org/10.1101/2025.06.02.657331
STAT3 signaling enhances tissue expansion during postimplantation mouse development
STAT3 signaling enhances tissue expansion during postimplantation mouse development
Azami et al. reveal that STAT3 deletion depletes epiblast cells at implantation, causing a persistent developmental delay of around a day. STAT3 null embryonic stem cells contribute to all embryonic tissues in chimeras except blood. Mixing with wild-type cells for in vitro erythroid differentiation causes the outcompetition of STAT3 null cells.
dlvr.it
Happy to share our study on Stat3, now published in Cell Reports! Huge thanks to all collaborators! www.cell.com/cell-reports...
STAT3 signaling enhances tissue expansion during postimplantation mouse development
Azami et al. reveal that STAT3 deletion depletes epiblast cells at implantation, causing a persistent developmental delay of around a day. STAT3 null embryonic stem cells contribute to all embryonic t...
cell.com