Today we welcome Professor Jenny Nichols (University of Edinburgh), who will talk about her work on early mammalian development. Host: Stan Strawbridge @stanleystrawbridge.bsky.social All welcome!

Very happy to have been part of such a fun and interesting project with an excellent team!

Anestis Tsakiridis@tsakiridis.bsky.social · 3mo ago

Our latest preprint is out: we used hPSC differentiation and quantitative modelling to dissect the role of Notch signalling, a pathway that is perturbed in Hirschsprung disease, a potentially lethal enteric neuropathy, in human enteric nervous system (ENS) progenitor dynamics (1/n)

🚨 New Preprint 🚨 "Quantification and statistical comparison of cell-state transition kinetics using a parametric failure-based model" doi.org/10.64898/202... Cells do not usually change state at a single fixed time. How can we compare these distributions across conditions? 🧵 1/3

⏰ Deadline Approaching! ⏰ 📅 15 January 2026 Under two weeks to apply for our fully funded PhD project “Engineering an in vitro human embryo implantation platform to study pathologies arising in early pregnancy” at @sheffielduni.bsky.social. #development #endometrium #materialsscience

I strongly encourage ECRs to apply for opportunities like the Travelling Fellowships from the ever supportive @biologists.bsky.social They are a fantastic for learning new skills, building collaborative networks, and honing scientific writing. doi.org/10.1242/dev....

The Company of Biologists Travelling Fellowships programme: a commitment to support the next generation of scientists

ABSTRACT. Between 2008 and 2025, four of The Company of Biologists' journals – Development, Journal of Cell Science (JCS), Journal of Experimental Biology (JEB) and Disease Models & Mechanisms (DMM) –...

doi.org

⏰ Deadline in two weeks! ⏰ Work at the interface of biology + computation to build a virtual human embryo to predict developmental success and failure. Happy to answer questions!

🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬 This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share! www.findaphd.com/phds/project... 🧪

🚨 PhD Projects 🚨 We are advertising two UKRI funded PhD projects at the @sheffielduni.bsky.social. #stemcells #development #embryology #reproductivephysiology #mathmaticalmodelling #quantitativebiology

🚨 New paper out in Development! 🚨 We show that donor embryonic stem cells (ESCs) reshape the developing mouse embryo, not just by what they signal, but where they push. 📄 doi.org/10.1242/dev.... [1/8]

1/10🧵 New preprint! 🚀 We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place. 👉doi.org/10.1101/2025.06.02.657331

Today’s speaker in our DRN external seminar series is Dr Thorsten Boroviak (PDN, University of Cambridge) @pdncambridge.bsky.social , who will talk on early embryonic development in primates. Host: Anestis Tsakiridis @tsakiridis.bsky.social All welcome!

Thanks to Anne Wiblin and the team at abcam for the invitation to share and discuss my research today! #stemcells #development

It was fantastic to have @lbates.bsky.social visit last week! Thank you for sharing your exciting work!

Development, Regeneration and Neurophysiology@drn-sheffield.bsky.social · last yr.

The speaker in our DRN external seminar series today is Dr Lawrence Bates @lbates.bsky.social from the University of Edinburgh @edinburgh-uni.bsky.social, presenting his work on early human development. Host: Stanley Strawbridge @stanleystrawbridge.bsky.social All welcome!

Check out our new research in @royalsocietypublishing.org's Open Biology! We experimentally induce a transition from chemical to mechanical patterning in the chicken embryo 🐣🔬 @lanevol.bsky.social 🧪 royalsocietypublishing.org/doi/10.1098/...

Exacerbated sonic hedgehog signalling promotes a transition from chemical pre-patterning of chicken reticulate scales to mechanical skin folding | Open Biology

Many examples of self-organized embryonic patterning can be attributed to chemically mediated systems comprising interacting morphogens. However, mechanical patterning also contributes to the emergenc...

royalsocietypublishing.org

TIL, I can get excited about a -80. #StrawbridgeLab #NewPI

Check out these feather buds on the chicken embryo's wing! Our latest study @plosbiology.org reveals that temporary inhibition of sonic hedgehog signalling transforms feathers into simple, protofeather-like structures—similar to those of their dinosaur ancestors🔬🦖🧪 journals.plos.org/plosbiology/...

A fantastic meeting of early career researchers in Vienna this week. It was great to see old friends and to meet new people. Thank you so much for the opportunity to present my work at SY-Stem 2025! @impvienna.bsky.social @imbavienna.bsky.social @maxperutzlabs.bsky.social

Thank you!!! @drn-sheffield.bsky.social and @sheffielduni.bsky.social has been and continues to be a welcoming and stimulating research environment!

Development, Regeneration and Neurophysiology@drn-sheffield.bsky.social · last yr.

A warm welcome to Stanley Strawbridge @stanleystrawbridge.bsky.social, who joins us as a #PhysicsOfLife & #QuantitativeBiology Fellow from @scicambridge.bsky.social. His work explores early human embryo form and function. #AdvancedImaging #AppliedMathematics #Bioengineering #stemcells #development

A warm welcome to Stanley Strawbridge @stanleystrawbridge.bsky.social, who joins us as a #PhysicsOfLife & #QuantitativeBiology Fellow from @scicambridge.bsky.social. His work explores early human embryo form and function. #AdvancedImaging #AppliedMathematics #Bioengineering #stemcells #development

It was great to be back @cambridgeuni.bsky.social to give a talk @gurdoninstitute.bsky.social Developmental Biology Seminar Series, and to talk science with people from @scicambridge.bsky.social, @loke-ctr.bsky.social, and @mrclmb.bsky.social! Spring has sprung @christscollegecam.bsky.social!

Fully funded #PhD Studentship with myself and JJ Phillips at the Living Systems Institute, @uniofexeter.bsky.social "Control of chromatin remodeller activity to direct cell fate decisions" #Chromatin #Transcription #StemCells #StructuralBiology Please re-skeet! www.exeter.ac.uk/research/ins...

LSI PhD programme | Living Systems Institute | University of Exeter

exeter.ac.uk

PhD positions available in the LSI www.exeter.ac.uk/research/ins... via the Wellcome Trust funded GW4 CAT PhD Programme for Health Professionals. Applications open now until 17.January 2025. @uniofexeter.bsky.social

See you there!

The Company of Biologists@biologists.bsky.social · 2y ago

Abstracts are due in one month for Biologists @ 100, a unique conference to celebrate our 100-year anniversary and bring together our different communities. We hope you can join us. Abstract deadline is 13 December. Submit yours at 100yearsconference.biologists.com/abstracts/ #biologists100

🚨 A PhD project to develop an in vitro human implantation platform is available with me and an interdisciplinary supervisory team at the University of Sheffield. #blastoids #endometrialAssembloids #stemCellBiology #embryology #biomaterials #advancedImaging #dataScience tinyurl.com/ycykmwv4