Coworker: hey, your wife sees a lot of new books, does she have one that tells a programmer how to be successful in business? Me: well, she specializes in science fiction Coworker 2: burn.
Matt
@tesel8s.bsky.social
Stewman in an ether factory. He/they. Los Angeles adjacent.
Without disrespect, I feel that giving the Nobel for this was like giving the Nobel to Noah Webster for "solving" spelling. It's a monumental effort, and kudos, but a really good educated guessing machine isn't a "solution". It provides no reductive laws or insights.
Alas poor AlphaFold, we knew you well... This is not entirely surprising to me, as it wasn't clear what more AF could do outside of what Hassabis is trying to build with Isomorphic. But I am interested in people's thoughts here #chemsky #biotech 🧪 www.ft.com/content/61b2...
I don’t know the first thing about “fambushing” but I’m 100% behind kids turning the nanny state around on their parents.
In case you’re in need of a long series of chuckles today, may I present:
honestly "Pickaxe Mountain" sounds less like a fortified nuclear facility and more like a spot the local prospector would be defending with at most a stick or two of dynamite
Oh the jails on pickaxe mountain They all are made of tin And you can walk right out again Just as soon as you are in
If anything, I think there should be more conceptual space for a pro-Israel-as-idea, anti-things-currently-happening-there position. But I would think this, as someone who, uh, thinks this.
Demis Hassabis seems to exhibit all the signs of what I'd like to think of as "Intelligence Chauvinism"...
A Framework for Frontier AI and the Dawning of a New Age
This is a pivotal moment in human history. Artificial General Intelligence (AGI), a system that exhibits all the cognitive capabilities the brain has, is probably only a few short years away.
open.substack.com
Hopemaxxing, Hypemaxxing, Fearmaxxing unsequenced.life/2026/05/15/h...
Hopemaxxing, Hypemaxxing, Fearmaxxing
Did you know that synthetic biology is going to save the world? Or possibly destroy it? Maybe both! Or neither, you know, whatever. It depends. But it’s going to change everything, and you be…
unsequenced.life
www.humblebundle.com/books/pathfi... So pleased to announce my new Humble Bundle exclusive short story! "From Author Gabrielle Harbowy (Gears of Faith) comes a new tale of the fan-favorite heroines (and their loyal riding dog companion, Appleslayer) set in Pathfinder's Lost Omens setting."
Humble RPG Bundle: Pathfinder Second Edition Bundle of Frogs! By Paizo Inc.
Set a course for adventure with this Pathfinder bundle featuring Dawn of the Frogs, Extinction Curse, and more! Pay what you want and support the Craft Emergency Relief Fund!
humblebundle.com
alt: a drawing of the "components of benzene" with a circle inside the ring. The circle's ring is labelled "benzene membrane," the outer ring layer "benzene wall" and the inside "benzoplasm."
There’s this window in the corner of a room at the Huntington that contrasts perfectly against the marble.
A man who publicly was doing something which, when done wrong, can cause graft-vs-host disease, an autoimmune disease which can attack, among other things, your GI tract, now has an autoimmune disease which is attacking his GI tract. What a coincidence.
Millionaire biohacker reveals he has incurable disease amid mission to ‘defeat death’
‘My stomach is eating itself,’ the tech entrepreneur announced on social media
the-independent.com
Blood transfusions from close relatives can cause graft vs host disease. Close relatives are literally the last people in the world rich weirdos should be roping into their creepy vampire hobby.
Vance just compared himself favorably to Richard fucking Nixon? www.theatlantic.com/newsletters/...
A Watergate Every Week
J. D. Vance contends that the scandal would be “a 12-hour news story” today. He’s probably correct, but the lesson isn’t what he claims.
theatlantic.com
The study of the mind and behavior of cats is called pspspsychology
Circa 2010 or so, Thiel used to hold court with a number of “thinkers” at dinner parties at his house. Did it not stick? Why is he so badly informed, if he’s seemingly put in the effort-time to consult others? …
It sort of makes me very irritated that Thiel also wants to spout off about religion and it's like, no, both Catholic theology and cancer are serious areas of scholarship, and YOU'RE A BILLIONAIRE, you could command the finest tutors in the world but instead you just wanna be a pundit
There's a Seanbaby turn of phrase that has really stuck with me, "the kind of thing that makes Satan shuffle the papers on his desk and go 'shit, do I even have a form for that?'"
BREAKING: DOJ reportedly launches criminal investigation into E. Jean Carroll
I think this is a splendid idea. I’d prefer, for reasons, it to be Reagan, but yeah 🧵 1/3
!!! Trump appointees at Treasury push for $250 bill with his face on it. Director of Bureau of Printing & Engraving, who resisted the effort, said she was involuntarily reassigned last month. “The buck stopped here,” she wrote in her goodbye. wapo.st/4fM4Hei
I wonder how old I’ll be when my livejournal is old enough that I don’t feel weird asking my livejournal out.
this is your six month notice that the character and tone of this account is about to transform, A LOT. If you're following me predominantly for my identity as a professional scientist, just be aware, I'm retiring soon. In general, I DGAF who knows my social or identity politics- but, heads up.
Online: tesel8s/tesel8me/“tes” My friends call me: Matt By day: scientist/chemist/pharma safety and mfg Hobbies: science projects/exhibits, photography, “Making”, cooking Pronouns: he/they Identity: out queer, GNC, sub. Married, ENM.
Sending a little support for a new hearing aid, one slowly-going-deaf person to another!
Trying to save up for a Hearing Aid🦻 so I’ll be opening comm, I’ll also offer sets on k0fi (nazunita) and custom stuff! Please help me 🙏 More info on sets and custom stuff: clownnita.uwu.ai More info on commissions vgen.co/nazunita nita.uwu.ai