‼️New review by @amandaanderssonr.bsky.social and @hansclevers.bsky.social discussing the latest applications for organoids is now out in Nature Reviews Molecular Cell Biology: “New developments and applications of human organoids.” 🧫 🔗Read here: www.nature.com/articles/s41...

New developments and applications of human organoids - Nature Reviews Molecular Cell Biology

Organoids are powerful tools for studying human development and disease mechanisms in vitro. This Review discusses their limitations and recent advances that increase their complexity to better mimic ...

nature.com

1/4 New in Science: Gut renewal is not passive “crowd control.” Instead of being pushed out by crowding or dying from apoptosis, cells compete in a mechanical tug-of-war. Weaker cells are eliminated—reframing intestinal homeostasis as a force-regulated process. www.science.org/doi/10.1126/...

Epithelial tension controls intestinal cell extrusion

Cell extrusion is essential for homeostatic self-renewal of the intestinal epithelium. Extrusion is thought to be triggered by crowding-induced compression of cells at the intestinal villus tip. In th...

science.org

Do you want to learn how to make mouse thymus organoids? Our lab recently published a STAR Protocol on generating thymic epithelial organoids from adult mouse thymus tissue. Read it here: doi.org/10.1016/j.xp... #Thymus #Organoids #STARProtocol #TEC

Our PhD student @samwillemsen.bsky.social presented our work on thymus organoids at this year’s Global Thymus Network meeting, ThymUS 2025. #ThymUS2025 #Organoids #Thymus

The Clevers lab is in Spain! Our postdocs Hanxiao, @sarinashabso.bsky.social, @amandaanderssonr.bsky.social and a PhD student @katarinabalazova.bsky.social are taking part in an @embo.org Workshop on Liver and Pancreas in Metabolic Diseases in Girona 🌞 #embo #liver #pancreas #girona

IFN-responsive intestinal BEST4/CA7+ cells are targets of bacterial diarrheal toxins @cp-cellstemcell.bsky.social @thecleverslab.bsky.social www.cell.com/cell-stem-ce...

Organoid drug profiling identifies methotrexate as a therapy for SCCOHT, a rare pediatric cancer www.science.org/doi/10.1126/... @thecleverslab.bsky.social

Check out this new article highlighting our postdoc @amandaanderssonr.bsky.social ’s work on a novel pancreatic organoid model that includes all three key cell types, offering new insights into pancreatic development: www.the-scientist.com/a-novel-thre...

A Novel Three-in-One Pancreatic Organoid

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and possible regeneration.

the-scientist.com

📢New human fetal pancreatic organoid model generates all three key cell types of the pancreas. New paper in @cellpress.bsky.social by @amandaanderssonr.bsky.social , @hansclevers.bsky.social and collaborators. See the article here: www.sciencedirect.com/science/arti...