If you're interested in our 'Inositol Phosphate and Pyrophosphate Signalling' meeting (abstract deadline Thursday!), you may be interested in these related articles from our journals 🧪 bit.ly/4xsXIfW

Join @blindlab.bsky.social, @structplantbio.bsky.social, @thelahalab.bsky.social and many others at Inositol Phosphate and Pyrophosphate Signalling in October, in the beautiful medieval city of York 🧪 bit.ly/4p16yP3

Lorraine Reese@lorraine-reese.bsky.social · last mo.

A ‘must attend’ event for everyone interested in cell signalling: Inositol Phosphate and Pyrophosphate Signalling promises a contemporary interpretation of the biology of this extraordinary class of cellular messengers. Submit your abstract and save £100 if booked by Monday 13 July! 🧪 bit.ly/4p16yP3

I am happy to share that the final version of our review on Metabolism, Perception, and Functions of Inositol (Pyro)Phosphates in Plants has been published. Many thanks to Ricardo Giehl @leibnizipk.bsky.social for this great collaboration - www.annualreviews.org/content/jour...

Metabolism, Perception, and Functions of Inositol (Pyro)Phosphates in Plants

Inositol phosphates and pyrophosphates are small, water-soluble molecules involved in a range of physiological processes across eukaryotic organisms, including plants. Over the past two decades, signi...

annualreviews.org

Deeply grateful to all co-authors for their contributions, especially Henning Jessen @jessenlab.bsky.social and Dorothea Fiedler for bringing their fantastic expertise to this project. Very happy to see this story published!

Nice piece of work. Congratulations to Gabriel, Martina and entire team!

Gabriel Schaaf@gabrielschaaf.bsky.social · 3mo ago

Excited to see our new Science Advances paper out! A wonderful collaboration with Martina Ried-Lasi’s group at IPB Halle. Many thanks to Kiran Raj and Verena Gaugler for their outstanding work, and to everyone involved who helped make this study possible. www.science.org/doi/10.1126/...

interested in inositol pyrophosphate interactors in plants? here is a complete list based on photoaffinity pulldown. congrats to Kevin and many thanks to all fantastic collaborators. advanced.onlinelibrary.wiley.com/doi/10.1002/...

Affinity‐Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6‐PP‐InsP5‐Binding Proteins in Plants

Inositol pyrophosphates (PP-InsPs) are central regulators of eukaryotic signaling events. While certain PP-InsP isomers have been conclusively linked to the regulation of phosphate homeostasis throug...

advanced.onlinelibrary.wiley.com

onlinelibrary.wiley.com/doi/10.1002/... Caged Magic Spot Nucleotides with 4 or 5 phosphates can now be delivered into living E coli cells and be released with light on demand. Congratulations to Christoph Popp for all the great work.

In celebration of Agrisera’s 40th anniversary, we have conducted a series of short interviews with scientists, who have supported the development of Agrisera's antibody collection. Read full interview with Assistant Prof. Debabrata Laha: www.agrisera.com/en/Agrisera-...

The expanding landscape of inositol phosphate signaling network in land plants - Ghosh - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/...

Our November issue is live! www.nature.com/nchembio/vol... The cover depicts a SEM image of a dorsal surface of liverwort M. polymorpha female thallus. Liverwort were found to have a noncanonical pathway for the regulation of master growth repressor DELLA.

Really delighted and humbled to see that we made it into cover! This is first time for us. Please see more details about work in PMID: 40745478.

Nature Chemical Biology@natchembio.nature.com · 10mo ago

Our November issue is live! www.nature.com/nchembio/vol... The cover depicts a SEM image of a dorsal surface of liverwort M. polymorpha female thallus. Liverwort were found to have a noncanonical pathway for the regulation of master growth repressor DELLA.

Happy to share our work on identification of non-archetypal activity of IPK2 in producing inositol pyrophosphate 4/6-IP7 and regulating heat stress acclimation-conserved in studied land plants. Grateful to @jessenlab.bsky.social for wonderful collaborative efforts! journals.plos.org/plosgenetics...

Conservation of heat stress acclimation by the IPK2-type kinases that control the synthesis of the inositol pyrophosphate 4/6-InsP7 in land plants

Author summary Inositol pyrophosphates (PP-InsPs) are eukaryote-specific cellular messengers that control a plethora of critical physiological processes, ranging from cellular metabolism to cellular e...

journals.plos.org

Delighted to share our work "GA-independent DELLA regulation by pyrophosphate in a nonvascular land plant" published now in Nature Chemical Biology! @natchembio.nature.com www.nature.com/articles/s41...

GA-independent DELLA regulation by inositol pyrophosphate in a nonvascular land plant - Nature Chemical Biology

A noncanonical pathway of DELLA regulation by a conserved inositol pyrophosphate synthase was identified in the liverwort, Marchantia polymorpha, that lacks the canonical gibberellin-induced DELLA deg...

nature.com

congrats to Kevin! His paper on new inositol pyrophosphates is out in @angewandtechemie.bsky.social doi.org/10.1002/anie...

Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP‐InsP4 Isomers in Plant Signaling

Inositol pyrophosphates (PP-InsPs) are highly phosphorylated signaling molecules that regulate diverse cellular processes, including phosphate homeostasis and energy metabolism across species. Despit...

doi.org

An alternative strategy to access inositol derivatives by stereoselective dephosphorylation. Happy to share the work by Markus Haener together with @gabrielschaaf.bsky.social and many others. chemrxiv.org/engage/chemr...

Stereoselective chemoenzymatic phytate transformations provide access to diverse inositol phosphate derivatives

Phosphorylated myo-inositols (InsPs) are essential cytoplasmic signaling molecules, while their lipidated analogs (PtdInsPs) play a crucial role in membrane signaling. Stereoselective synthesis of the...

chemrxiv.org

The final version of our study on SERK-BIR module in Marchantia is out. Congratulations Cate and many thanks to collaborators! www.sciencedirect.com/science/arti...

Conserved role of the SERK-BIR module in development and immunity across land plants

SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASES (SERKs), which are subfamily II of leucine-rich repeat receptor-like kinases (LRR-RLKs), play diverse role…

sciencedirect.com

Marc Somssich@somssich.bsky.social · 2y ago

New work from @grandpahiro.bsky.social's lab here at the MPIPZ in Cologne: "Conserved role of the SERK-BIR module in development and immunity across land plants" They looked at the evolution of the SERK co-receptors. www.biorxiv.org/content/10.1... #PlantScience #PlantEvoMPMI #PlantEvoDevo

Happy to share Kevin´s great work on PP-InsP4 synthesis and analysis now available on Chemrxiv! chemrxiv.org/engage/chemr...

Expanding the PP-INSP₄ Toolbox: Synthesis, Stereochemical Assignment, and Application in Plant Phosphate Signaling

Inositol pyrophosphates (PP-InsPs) are highly phosphorylated signaling molecules that regulate diverse cellular processes, including phosphate homeostasis and energy metabolism across species. Despite...

chemrxiv.org