Bob C-J and Geoff Cumming
@thenewstats.bsky.social
Open science, estimation statistics, and random thoughts from Bob Calin-Jageman and Geoff Cumming. https://thenewstatistics.com/itns/
New paper on DaBest 2.0, outlining its cool visualizations for complex designs. For both R and python, DaBest is a fantastic, easy tool for focusing on effect sizes and uncertainty. #statsky www.nature.com/articles/s41...
Getting over ANOVA: estimation graphics for multi-group comparisons - Nature Methods
Nature Methods - Getting over ANOVA: estimation graphics for multi-group comparisons
nature.com
Today we launch the first stable release of RegCheck: v1.0.0. RegCheck makes it easier and quicker to compare study registrations to published papers for consistency - something we know is important in principle, but rarely done in practice. A 🧵 on what's new: regcheck.app
RegCheck
RegCheck is an AI tool to compare preregistrations with papers instantly.
regcheck.app
Receive up to $1000 from @FUNFaculty to subsidize your travel costs to SfN 2026 in Washington D.C. Applications must be submitted by a FUN faculty member in good standing. Researchers presenting undergraduate research, even if they have already graduated, are…
Will there be a PSE9? Have the dates/locations been determined yet? (trying to plan before my university cuts faculty travel again) @lakens.bsky.social @annaveer.bsky.social
OMB's proposed rule threatens the foundation of scientific discovery. Join SfN’s Advocacy Team & legislative advisors for this members-only town hall about the rule & other recent actions that have the potential to affect the scientific enterprise. 🔗 vist.ly/584nt #neurosky
My buddy Richard Olivo have often talked about how our curmudgeonly takes on the state of #neuroscience makes us feel like we're Statler and Waldorf. Now AI can let us see what that'd look like... and it is spot on!
Psychologists Help Society in so Many Ways thenewstatistics.com/itns/2026/04... Portrait below of Ron Cumming, aeronautical engineer, psychologist, pioneer (with Ross Day) of human factors in Australia
This is us!! This is the sluglab!!
The Transmitter @thetransmitter.bsky.social · 3mo agoMemory formation needs transcription, but memory maintenance may not. A new study adds nuance to a foundational neuroscience question. #neuroskyence By @siddhantpusdekar.bsky.social www.thetransmitter.org/memory/new-s...
Recent work from our lab got a lovely write up in @thetransmitter.bsky.social today, summarizing the ongoing mystery of memory maintenance. #neuroscience www.thetransmitter.org/memory/new-s...
New work questions how long-term memories are maintained
An experiment in sea slugs suggests transcriptional changes might fade after 24 hours.
thetransmitter.org
All the more reason to use systematic software designed to tackle this very problem, like RegCheck (regcheck.app)
RegCheck
RegCheck is an AI tool to compare preregistrations with papers instantly.
regcheck.app
Brendan Nyhan@brendannyhan.bsky.social · 3mo agoJournal editors - the status quo on preregistration is not working! You need to check submissions vs. preregistrations before sending articles out for review. *56%* of experiments I reviewed in last year have severe problems with non-disclosure, undocumented deviations, & more - see Claude summary ↓
1. The paper with the implausibly large effects of Omega-3 fatty acids on mental health was now retracted. A little thread on the process where @ianhussey.mmmdata.io and I was involved. www.sciencedirect.com/science/arti...
RETRACTED: The effects of Omega-3 supplementation on stress, anxiety, depression, sleep quality, and everyday memory in individuals with psychological distress: A randomized, double-blind, placebo-con...
This article has been retracted: please see Elsevier policy on Article Correction, Retraction and Removal (https://www.elsevier.com/about/policies-and…
sciencedirect.com
Martin Plöderl@ploederl.bsky.social · 7mo agoHurray, Omega-3 ends all mental suffering! Reduction of stress, anxiety, and depression with SMD > 3! Quite a lubricated review process, too: Received 8 Sep 2025; Revised 17 Nov; and accepted on Christmas (24 Dec). www.sciencedirect.com/science/arti...
The Faculty for Undergraduate Neuroscience Teaching Workshop will take place July 15-19 at North Central College, just outside of Chicago. Registration is open (tinyurl.com/fun2026nc) and you can still submit a poster. Keynotes include Michell Miller and Alexxai Kravitz. #neuroscience
Up to 2008 there were over 1700 published gene/schizophrenia association studies implicating over 1000 genes. Now none of these studies are viewed as useful. -- Legge et al., 2025 What a fascinating post-mortem this would make for a meta-science project. #neuroscience #stats #metascience
BOLD is not a simple monotonic readout of local firing. Instead, it reflects the net activity of two opposing neural populations. Interpreting it may require modeling their latent composition, not just overall activity. www.nature.com/articles/s41... #neuroscience
Brainwide blood volume reflects opposing neural populations - Nature
Combined functional ultrasound imaging and Neuropixels recording of mouse brains identify two neuronal populations with opposing arousal-related activity and distinct haemodynamic response functi...
nature.com
Just saw David Byrne’s Theater of the Mind and let me save anyone reading this $100: skip it. No matter how much you like the talking heads or David Byrne. The show is bad, bad, bad: treacly pablum with some neuroscience demos awkwardly mixed in. 75 minutes and $100 you won’t get back.
Simulator of the following (attentional) models: 🔎 Rescorla-Wagner 🔎 Pearce-Kaye-Hall 🔎 Mackintosh Extended 🔎 Le Pelley’s Hybrid 🔎 Rescorla-Wagner with a unified variable learning rate (integrating Mackintosh’s and Pearce and Hall’s quasi-opposing conceptualisations). github.com/cal-r/PALMS-...
Esther Mondragón@e-mondragon.bsky.social · 6mo agoNew preprint and simulator of associative learning attentional models. Have fun! 👁️ arxiv.org/abs/2602.07519 cal-r.org/index.php?id... #simulation #associative_learning #attention
esci produces lovely figures of effect sizes with CIs for most common designs. It's catching on: In March 2026, esci was downloaded over 2700 times in jamovi and another 700 times in CRAN. Still lots of rough edges-- send feature requests and feedback my way! github.com/rcalinjagema... #stats
SCORE, a collaboration of 865 researchers, is now released as three papers in Nature, six preprints, and a lot of data (cos.io/score/). SCORE examined repeatability of findings from the social-behavioral sciences and tested whether human and automated methods could predict replicability.
SCORE | Center for Open Science
SCORE shows that there is no shortcut to producing credible research findings, and there is no single indicator of trustworthiness. Research progress depends on transparency, rigor, and establishing r...
cos.io
Who says null results are uninteresting? Here, our lab shows that most transcriptional changes fade *before* memory expression. This is surprising, and raises lots of interesting questions about how long-term memories are maintained. #neuroskyence #stats www.eneuro.org/content/13/3...
Transcriptional Changes Fade Prior to Long-Term Memory for Sensitization of the Aplysia Siphon-Withdrawal Reflex
Forming a long-term memory requires changes in neuronal transcription. What happens, though, as the memory is forgotten? And how does the transcriptional state relate to the maintenance and recall of ...
eneuro.org
Genuinely a thrill to see figures created with esci popping up in papers. Here's one from a meta-analysis of antibiotic residues in food in Southern Africa... something I know nothing at all about, but apparently esci came in handy. www.sciencedirect.com/science/arti... #stats
More evidence that intranasal oxytocin does not reliably impact trust: www.sciencedirect.com/science/arti... Cool work from @wviechtb.bsky.social, @leonieseidel.bsky.social, @dhernaus.bsky.social and others. #neuroskyence #stats.
Absence of a meaningful effect of intranasal oxytocin on trusting behavior: a registered report with pooled equivalence testing
The neuropeptide oxytocin (OXT) is thought to modulate important aspects of prosocial behavior. In a seminal paper, Kosfeld et al. (2005) reported tha…
sciencedirect.com
doi.org/10.1111/jep.... Statistical reform spreads around the world and across disciplines: Beyond the p Value Dichotomy: Alternatives for Statistical Inference—A Critical Review
thenewstatistics.com/itns/2026/03... We want the best research methods–of course–but should also consider philosophy, ethics, global heating and health.
The eNeuro "Improving Your Neuroscience" series continues with a two-part primer on experimental design and blocking from Penelope Reynolds. These new guides will help you up your design game. #stats #neuroscience www.eneuro.org/content/13/2... www.eneuro.org/content/13/2...
Experimental Designs for Preclinical Neuroscience Experiments: Part I—Design Basics
Rigorous, statistically grounded experimental design is central to ethical and effective animal research. Foundational principles for statistically based Design of Experiments (DOE) were established o...
eneuro.org
Scientists created prosthetic barn-owl ears and got human participants to wear them for 3-59 days. Yes, people walked around with barn-owl ears for up to 2 months *for science*. This is the type of news I need today to restore a bit of my faith in humanity. www.biorxiv.org/content/10.6...
Sterling, 1959 updated. We still aren’t sharing science in a scientific manner. With 65 years of knowing the problem, how are we still struggling to address it?
Ryan Briggs@ryancbriggs.net · 6mo agoI have a new paper. We look at ~all stats articles in political science post-2010 & show that 94% have abstracts that claim to reject a null. Only 2% present only null results. This is hard to explain unless the research process has a filter that only lets rejections through.
So excited to see DaBest 2.0 is out: get bootstrapped estimation statistics for simple through complex designs, all with beautiful visualization, available in R and Python. Check it out! Pre-print describing new features for complex designs: www.biorxiv.org/content/10.6... #stats
Getting over ANOVA: Estimation graphics for multi-group comparisons
Data analysis in experimental science mainly relies on null-hypothesis significance testing, despite its well-known limitations. A powerful alternative is estimation statistics, which focuses on effect-size quantification. However, current estimation tools struggle with the complex, multi-group comparisons common in biological research. Here we introduce DABEST 2.0, an estimation framework for complex experimental designs, including shared-control, repeated-measures, two-way factorial experiments, and meta-analysis of replicates. ### Competing Interest Statement The authors have declared no competing interest.
biorxiv.org
