A great couple of days in Nagoya with many excellent talks and discussions.

MRC Biostatistics Unit@mrc-bsu.bsky.social · last mo.

🤩 Fantastic BSU presence at the 18th World Meeting of the International Society for Bayesian Analysis in Nagoya, Japan last week, with lots of of our brilliant staff and students presenting their work and building new connections. #ISBA2026

We are delighted to be hosting MASAMB 2026. This year's conference will have a strong focus on interdisciplinary collaboration and early-career researchers. Abstract submission for talk and poster presentations is now open. Deadline: 15 May 👇 docs.google.com/forms/d/1--e...

New paper in The Lancet Psychiatry, with @thomasjaki.bsky.social as co-author, about the GAINS-2 Trial - A Bayesian adaptive randomised trial which uses a digital intervention to combat the trauma UK healthcare workers experienced during the COVID-19 pandemic. www.sciencedirect.com/science/arti...

A digital imagery-competing task intervention for stopping intrusive memories in trauma-exposed health-care staff during the COVID-19 pandemic in the UK: a Bayesian adaptive randomised clinical trial

Psychological trauma, such as witnessing an untimely or gruesome death, commonly provokes intrusive memories that might persist for days to years with…

sciencedirect.com

@lshtm.bsky.social will be running a 3-day online short course on using multiple imputation to handle missing data on 23-25th June 2026. Teaching staff include James Carpenter, Ruth Keogh, Clémence Leyrat, and myself. Further details about the course at www.lshtm.ac.uk/study/course...

Libby Daniells from the BSU and colleagues have developed a new technique to improve the reliability of #ClinicalTrials. Read more 👇 www.mrc-bsu.cam.ac.uk/news/incorpo... Paper in Biostatistics 👇 academic.oup.com/biostatistic...

Yesterday I received a grant rejection. Obviously very disappointed, but at least one of the reviewers recognised that I was a young researcher with potential.

Back in Germany and looking at a full day of teaching. At least it is Winter wonderland here.

Final day of my trip to Australia and finishing with a bang: AusTRiM conference starting of with a session on rare diseases.

Good Morning Melbourne. Lovely debate at the ACTA symposium yesterday on "Is AI Driving Smarter, Faster, Fairer Clinical Trials".

Had a great day yesterday talking at ACTA about Evaluating AI algorithms for healthcare.

A great couple of days at the University of Queensland. Never thought I'd take a ferry to work.

A wonderful day @UQ. Looking forward to continuing discussions around trials for chronic pain.

Unglaublich was gerade in Wien abgeht. Die Kürzungen betreffen nicht nur die Beschäftigten, sondern gehen uns alle an. Bitte unterstützt die Petition: mein.aufstehn.at/petitions/st...

Stoppt den Kahlschlag im Wiener Sucht- und Drogenhilfenetzwerk - SDHN

Sucht ist eine Erkrankung, die viele Personen in Österreich betrifft.    Eine Kürzung der Angebote für Suchterkrankte betrifft damit uns alle, • als Betroffene oder als Angehörige • als Steu...

mein.aufstehn.at

Incorporating historic information to further improve power when conducting Bayesian information borrowing in basket trials academic.oup.com/biostatistic...

Incorporating historic information to further improve power when conducting Bayesian information borrowing in basket trials

ABSTRACT. In basket trials a single therapeutic treatment is tested on several patient populations simultaneously, each of which forming a basket, where pa

academic.oup.com

Design of platform trials with a change in the control treatment arm academic.oup.com/biometrics/a...

Design of platform trials with a change in the control treatment arm

ABSTRACT. Platform trials are an efficient way of testing multiple treatments. We consider platform trials where, if a treatment is found to be superior to

academic.oup.com

Fantastic two days of stimulating talks and discussions at our Workshop on Adaptive and Bayesian Designs in Real Trials, where statisticians, clinicians and patients have shared their experiences of #ClinicalTrials. Thanks to all our speakers and all those who attended.

A thought provoking event. Glad I could participate.

MRC Biostatistics Unit@mrc-bsu.bsky.social · last yr.

Our Ethics and Innovative Trial Designs Workshop has kicked off with @thomasjaki.bsky.social speaking on routinely used and complex adaptive designs.

(1/2) Another action packed day at the workshop on Adaptive Designs and Multiple Testing Procedures in Regensburg, with great talks from BSU researchers and PhD students - Gianmarco Caruso, Stef Baas and James Willard.

David Robertson and Thomas Jaki are organising a workshop on Adaptive Designs and Multiple Testing Procedures, happening today and tomorrow in Regensburg. admtp.github.io/ADMTP2025/ BSU PhD students, Connor Fitchett and Weishi Chen, have presented today.

The deadline to apply for a @mrc-bsu.bsky.social PhD studentship has been EXTENDED to March 27, 2025! 🗓️✨ Explore the exciting PhD projects available here: www.mrc-bsu.cam.ac.uk/phd-opportun... 🔍📚 🌟 Special shoutout to the project by @thomasjaki.bsky.social and myself 👼

I suspect many of us need to hear this today. @charliemackesy1.bsky.social

Bioresonanz. Die Älteren von euch erinnern sich ja daran, dass ich diese Studie so mag. link.springer.com/article/10.1... Warum ist diese Studie so toll? Weil keine andere Studie Bioresonanz an Menschen, Leberkäse(!), einem feuchten Tuch sowie einem Leichnam(!) ausprobiert hat. Ein paar Zitate:

Einfache Testverfahren zur Überprüfung der Aussagekraft von Bioresonanz-basierten medizinischen Befunden — der Leberkäse-Test - Allergo Journal

Allergo Journal - Trotz aller Aufklärungsarbeit wird die Bioresonanz weiter benutzt. Seit einigen Jahren sind modifizierte Geräte auf dem Markt, die auch in Reformhäusern zum Einsatz...

link.springer.com

I am looking for a PhD student in Medical Statistics. This project aims to develop new methods for design of early phase trials starting from monotherapy and progressing into combinations. More details are in the link. Feel free to contact me if any questions. www.findaphd.com/phds/project...

Designs for sequences of early phase (modular) studies at University of Cambridge on FindAPhD.com

PhD Project - Designs for sequences of early phase (modular) studies at University of Cambridge, listed on FindAPhD.com

findaphd.com

Interested in learning about Bayesian Clinical Trials? We are running a 2-day short course (24th-25th February 2025) on the topic directly prior to the Adaptive Designs and Multiple Testing Procedures Workshop. To register and more information visit admtp.github.io/ADMTP2025/co...

Our 3 day short course @lshtm.bsky.social on multiple imputation for missing data using R is now open for registration. 17-19 June 2025. This year the course will be online only. More info here: www.lshtm.ac.uk/study/course...

Our design for the early phase platform AGILE for treatments for COVID-19 has just been published. journals.sagepub.com/doi/10.1177/...

A seamless Phase I/II platform design with a time-to-event efficacy endpoint for potential COVID-19 therapies - Thomas Jaki, Helen Barnett, Andrew Titman, Pavel Mozgunov, 2024

In the search for effective treatments for COVID-19, the initial emphasis has been on re-purposed treatments. To maximize the chances of finding successful trea...

journals.sagepub.com

Our part 2 series paper in peer review... Confidence intervals for adaptive trial designs II: Case study and practical guidance arxiv.org/abs/2411.08771

Confidence intervals for adaptive trial designs II: Case study and practical guidance

In adaptive clinical trials, the conventional confidence interval (CI) for a treatment effect is prone to undesirable properties such as undercoverage and potential inconsistency with the final hypoth...

arxiv.org

Our part 1 series paper in peer review ... Confidence intervals for adaptive trial designs I: A methodological review arxiv.org/abs/2411.08495

Confidence intervals for adaptive trial designs I: A methodological review

Regulatory guidance notes the need for caution in the interpretation of confidence intervals (CIs) constructed during and after an adaptive clinical trial. Conventional CIs of the treatment effects ar...

arxiv.org

Registration is open for the next Adaptive Designs and Multiple Testing Procedures Workshop (taking place on 26th-27th February 2025 in Regensburg, Germany). For further details and to register, please see admtp.github.io/ADMTP2025/regi…