I am delighted to be able to share that our latest paper arising from a project co-led by @drsarahboyle.bsky.social and me is now out in the world, published in AAAS Science Advances. www.science.org/doi/10.1126/...

Compressive stress–driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory

Compressive force drives PIEZO1-RHO-ROCK mechanotransduction and establishes an epigenetic memory that promotes tumor progression.

science.org

We are very excited to share our newest results, published in Science Advances: “Compressive stress-driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory”. doi.org/10.1126/scia...

Compressive stress–driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory

Compressive force drives PIEZO1-RHO-ROCK mechanotransduction and establishes an epigenetic memory that promotes tumor progression.

doi.org

dx.doi.org/10.1126/scia...

Compressive stress–driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory

Compressive force drives PIEZO1-RHO-ROCK mechanotransduction and establishes an epigenetic memory that promotes tumor progression.

dx.doi.org

Why ‘being squeezed’ helps breast cancer cells to thrive “intense physical pressure at early stages of the disease… leaves a lasting ‘mechanical memory’ in breast cancer cells, promoting aggressive behaviour after the pressure itself has been relieved.” www.eurekalert.org/news-release...

Why ‘being squeezed’ helps breast cancer cells to thrive

A new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.

eurekalert.org

In a study co-led by myself and Prof @tmem-samuel.bsky.social at The Centre for Cancer Biology, Adelaide University, we found breast cancer cells subjected to compression, such as experienced during tumour growth in the restricted mammary duct, are changed in ways that worsen the resulting tumours.

Meet our invited Plenary and Keynote speakers! #HunterMeetingOz #JodiNunnari a pioneer in #mitochondrial biology, all the way from California #AltosLabs. Supported by Australia & NZ's leading #cell and #DevBio society #ANZSCDB @anzscdb.bsky.social

@drubin.bsky.social - another speaker joining us at #HunterMeetingOz from California's @ucberkeleyofficial.bsky.social #Cytoskeleton #MembraneTrafficking

#OdineCleaver joining the #HunterMeetingOz from Texas #UTSW @utswtxid.bsky.social a leader in blood vessel development and #organogenesis. #VascularBiology

@jacobhanna.bsky.social a #PluripotentStemCell & #SyntheticEmbryo expert all the way from the Weizmann #HunterMeetingOz

@judithklumperman.bsky.social joining the #HunterMeetingOz from University Medical Center #UMC Utrecht an #EM Expert in #lysosomes and #neurodegeneration

#LaiGuanNg joining the #HunterMeetingOz from #Shanghai #JiaoTongUniversity a leader in #MyeloidCell biology.

The Hunter Meeting has made it to the blue place! 🔵 If you are joining us in the beautiful #HunterValley 2-5 June 2025 - please tag us or search #HunterMeetingOz to follow along. #STEM #CellBiology #DevBio #SpatialOmics @anzscdb.bsky.social #AustralianMeeting

Our lab is seeking a postdoctoral scientist to join us to investigate modelling cancer extracellular matrix structures using nanofabrication approaches. Full details are at shorturl.at/fF4OC. Please feel free to alert anyone you know with suitable qualifications to this opportunity. Thank you!

Extremely happy for our team led by @tmem-samuel.bsky.social to have secured an NHMRC Ideas Grant, investigating how distinct ECM structures can influence cancer growth and metastasis. But, more support needed for EMCR apps to foster next gen of emerging leaders. www.unisa.edu.au/media-centre...

Cancer, birth defects and AI under the health microscope in 2025

NHMRC cancer cancer research national health and medical research

unisa.edu.au

ARC says they’ll release the Discovery Projects 2025 outcomes tomorrow. Recently, outcomes announcements have tended to happen at/around 11am Canberra time. My bot will pick up the announcement in RMS’s database and post immediately. Good luck!

Excellent resource for the biological/medical sciences community on Bluesky.

Johanna Joyce@johannajoyce.bsky.social · 2y ago

Inspired by the other amazing starter packs - here's one for cancer researchers! I tried to make this broad - from immunology to genomics to cell biology and so much more.. This list also includes organizations & institutes supporting cancer researchers 🧪🔬⚕️🩺 Hope its useful! go.bsky.app/FEoaJMc

Super cool for so many of us ➡️ The Human Tumor Atlas Network (HTAN) is constructing 3D atlases of the cellular, morphological, molecular, and spatial features of human #cancers (and their #microenvironments) over time 🧪 #mechanobiology #microscopy #physicsoflife www.cancer.gov/about-nci/or...

Human Tumor Atlas Network (HTAN)

The Human Tumor Atlas Network (HTAN) is constructing 3-dimensional atlases of the cellular, morphological, molecular, and spatial features of human cancers (and their surrounding microenvironments) ov...

cancer.gov