In case you missed it, the ARC now has rough time-lines for introducing the new schemes 👇

Giulia Gizzi@giulia-gizzi.bsky.social · last wk.

Looks like there are some tentative timelines that have been published now as well www.arc.gov.au/revitalised-...

Saturday I had the opportunity to attend Netball Australia's Adelaide Thunderbirds vs Queensland Firebirds PLAY4PINK round, raising money for breast cancer research together with principal charity partner The Hospital Research Foundation Group, and speak on a panel with Ali Clarke and Paul Flynn.

I am delighted to be able to share that our latest paper arising from a project co-led by @drsarahboyle.bsky.social and me is now out in the world, published in AAAS Science Advances. www.science.org/doi/10.1126/...

Compressive stress–driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory

Compressive force drives PIEZO1-RHO-ROCK mechanotransduction and establishes an epigenetic memory that promotes tumor progression.

science.org

Why ‘being squeezed’ helps breast cancer cells to thrive “intense physical pressure at early stages of the disease… leaves a lasting ‘mechanical memory’ in breast cancer cells, promoting aggressive behaviour after the pressure itself has been relieved.” www.eurekalert.org/news-release...

Why ‘being squeezed’ helps breast cancer cells to thrive

A new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.

eurekalert.org

We are very excited to share our newest results, published in Science Advances: “Compressive stress-driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory”. doi.org/10.1126/scia...

Compressive stress–driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory

Compressive force drives PIEZO1-RHO-ROCK mechanotransduction and establishes an epigenetic memory that promotes tumor progression.

doi.org

October is breast cancer awareness month. 🎀 I spoke with Australian Breast Cancer Research on what to look out for, when to take action, and how to look out for your loved ones. The earlier breast cancer is detected, the better the chances of survival. www.instagram.com/reel/DQX9N45...

Very excited to be at the Proteoglycan and Matrix Biology Society of ANZ conference this week! 🔬👩‍💻Looking forward to some great talks and seeing colleagues. (Also, churros for afternoon tea 😮)

Closing out the meeting is Tim Sargeant with an engaging plenary on the “trash bags” of the cell (autophagy)!

Sarah Boyle@drsarahboyle.bsky.social · 10mo ago

Pleasure to then chair fascinating presentations in the ECR/MCR session at the ANZSCDB Adelaide Meeting 🪑🗣️

Pleasure to then chair fascinating presentations in the ECR/MCR session at the ANZSCDB Adelaide Meeting 🪑🗣️

Sarah Boyle@drsarahboyle.bsky.social · 10mo ago

Nice talk by our student @mogana-rajkumar.bsky.social on ROCK signalling in Metastasis at the ANZSCDB Adelaide Meeting.

Nice talk by our student @mogana-rajkumar.bsky.social on ROCK signalling in Metastasis at the ANZSCDB Adelaide Meeting.

Sarah Boyle@drsarahboyle.bsky.social · 10mo ago

Attending the 13th Adelaide Meeting of the ANZSCDB today, kicked off with a mesmerising seminar from @melaniedwhite.bsky.social.

Attending the 13th Adelaide Meeting of the ANZSCDB today, kicked off with a mesmerising seminar from @melaniedwhite.bsky.social.

Medical Research Future Fund: Advocates urge increased disbursements amid US research cuts “the government could release as much as $1.4 billion each year, more than double the current amount.” Funding delivers breakthroughs! ⁦‪ www.theage.com.au/politics/fed...

Billions going unspent from Australia’s $24b medical research fund

Costings commissioned by independent MP Monique Ryan reveal the government could double how much funding it gives to innovative health research each year.

theage.com.au

What an honour to be able to don the puffy hat again yesterday, to give the oration at a University of Adelaide graduation ceremony for the Faculty of Sciences, Engineering and Technology. Truly delighted to be asked. Congrats to all the graduates and wishing you the very best!

Bubna-Litic, M., & Mayor, R. (2025). Beyond mechanosensing: How cells sense and shape their physical environment during development. Current opinion in cell biology, 94, 102514. #EpithelialMechanicsReview buff.ly/Ea2ZoFg

.@ahxanjaved.bsky.social, @sarawickstrom.bsky.social & team discover that Piezo1 balances membrane & cortex tension to stabilize intercellular junctions & maintain the epithelial barrier. journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/... #OpenAccess

Tiny molecular spirals in cells can scale up to control the twist and turn of entire tissues, an important step towards understanding left-right symmetry in tissues and organs. buff.ly/2pSf3xS

Just simple antibody optimisations, but it feels good to be back doing lab work after a year away from the bench. 🔬🥼👩‍🔬 #immunofluorescence #confocal

Was my pleasure to moderate the panel today at the inaugural Female Fellows symposium “Balancing Acts”. An insightful, open and frank discussion on juggling a scientific career with caring, part time work and leave, and a real sense of solidarity.

Absolutely thrilled to receive an AIPS 2025 SA Young Tall Poppy Award! Wouldn't be possible without our wonderful team, dedicated patient advocates, & various funding bodies that allowed me to connect with scientific/non-scientific groups to communicate our research. www.unisa.edu.au/media-centre...

Our Poppies the pick of the bunch

Six researchers from the University of Adelaide and University of South Australia have been named as this year’s South Australian Young Tall Poppies.

unisa.edu.au

Finally got the time to put together my awesome new Lego, The Evolution of STEM 🧬🔬🧪🚀

Come work with us! Seeking a Research Associate/Fellow to work on our NHMRC funded project using nanofabrication to model tumour ECM structures.

Michael Samuel@tmem-samuel.bsky.social · last yr.

Our lab is seeking a postdoctoral scientist to join us to investigate modelling cancer extracellular matrix structures using nanofabrication approaches. Full details are at shorturl.at/fF4OC. Please feel free to alert anyone you know with suitable qualifications to this opportunity. Thank you!

Happy birthday, David Attenborough! 99 ways he has inspired us, by Barack Obama, Billie Eilish, Morgan Freeman – and many more

Happy birthday, David Attenborough! 99 ways he has inspired us, by Barack Obama, Billie Eilish, Morgan Freeman – and many more

This week the presenter turns 99. To celebrate, we asked 99 nature lovers – including Margaret Atwood, Jane Fonda, Bono, Kate Winslet and Michael Palin – how he has helped us see the world with fresh eyes

theguardian.com

A bit late to the party, but finished Lessons in Chemistry by Bonnie Garmus. POV as a reader: captivating, funny, gripping story, relatable in professional sense. As a woman in science: Fantastic to see how far we’ve come, but some aspects still unfortunately resonate. Recommend!

ITGB1/FERMT1 mechanoactivation enhances CD44 characteristic stemness in oral squamous cell carcinoma via ubiquitin-dependent CK1α degradation www.nature.com/articles/s41...

ITGB1/FERMT1 mechanoactivation enhances CD44 characteristic stemness in oral squamous cell carcinoma via ubiquitin-dependent CK1α degradation - Oncogene

Oncogene - ITGB1/FERMT1 mechanoactivation enhances CD44 characteristic stemness in oral squamous cell carcinoma via ubiquitin-dependent CK1α degradation

nature.com

Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes www.nature.com/articles/s41...

Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes - British Journal of Cancer

British Journal of Cancer - Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes

nature.com

Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...

Measuring and manipulating mechanical forces during development - Nature Cell Biology

This Review discusses the recent advances in experimental approaches to interrogate the mechanical forces that mediate tissue deformations during development, highlighting the insights afforded at bot...

nature.com

Inhibiting fibronectin assembly in the breast tumor microenvironment increases cell death and improves response to doxorubicin https://www.biorxiv.org/content/10.1101/2025.02.12.637963v1

Hey folks! I got a tattoo of my beloved PIEZO ion channel on my arm! Now I can show how they activate (flatten) under pressure by flexing—Will add a bit of performance art to my science talks 🧪🧠.

Today on #InternationalDayofWomenandGirlsinScience, I’m reflecting on where I’m at. Pausing and slowing things down to raise a family takes its toll on an academic career in so many invisible ways, but it pushes me to work harder. This little babe (me!) knows it’s worth it.

Really enjoyed this session put together by @themeshwork.bsky.social. Always good to hear about the latest research and meet new people in the mechano field!

The Meshwork@themeshwork.bsky.social · last yr.

A truly amazing and inspiring session on Advances in Mechanobiology!!! Huge thanks to @drsarahboyle.bsky.social @carstenschulte4.bsky.social @mathildemathieu.bsky.social for sharing their research with the rest of us and @ccstorytime.bsky.social for moderating!!!! See u all in the next!!!