Glad to share this Viewpoint on Dual IRE1 targets, now out in @febsj.bsky.social. With @tonyavril.bsky.social, Eva Billat and Léane Legrand, from the PROSAC team @csignaling.bsky.social. febs.onlinelibrary.wiley.com/doi/10.1111/...
FEBS Press
IRE1 is an ER stress sensor that restores protein homeostasis through two signaling activities: XBP1s, which upregulates its target gene expression or RIDD which downregulates its target transcripts....
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