Tony Cunningham

@tonycunningham.bsky.social

Fiona & Cormac's dad | Assistant Professor & Director of the Center for Sleep & Cognition (CfSC) at Harvard Medical School & Beth Israel Deaconess Med Center | Licensed Clin Psychologist #BLM he/him Go Irish!☘️ https://www.centerforsleepandcognition.com/

How much can 15 days of a disrupted sleep-wake schedule change the emotional brain? Wang et al. found reduced gray-matter volume across multiple left amygdala subregions after experimentally induced circadian disruption, with larger reductions associated with worse sleep quality. buff.ly/aI2w7Br

Impact of circadian rhythm disruptions on the emotional brain: gray matter and functional connectivity changes in the amygdala - Translational Psychiatry

Translational Psychiatry - Impact of circadian rhythm disruptions on the emotional brain: gray matter and functional connectivity changes in the amygdala

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Does sleep process a stressful day differently from a neutral one? Hein et al. found that stress before bed ⬇️ SO–spindle coupling & disrupted the relationship between NREM low-frequency activity & overnight memory retention—particularly for emotional material. buff.ly/cQIDVSN

CBT-I may help during hypnotic tapering, but the evidence for actually getting people off medication is less clear. Zhang et al.’s meta-analysis of 13 RCTs found no reliable improvement in complete benzodiazepine/Z-drug discontinuation, despite some benefit for insomnia symptoms. buff.ly/tH1HFy9

Sage Journals: Discover world-class research

Subscription and open access journals from Sage, the world's leading independent academic publisher.

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Fear learning may actually make some hippocampal representations more similar. In mice, Rozeske et al. found greater threat/neutral overlap in ventral CA1, which predicted faster reinstatement of the fear memory. Might be why it's harder to overwrite those memories! buff.ly/06J8o4X

Overlapping representations in the ventral hippocampus support rapid fear memory retrieval - Nature Neuroscience

Fear learning increases the similarity of threatening and neutral context representations in ventral CA1, which may enable faster reinstatement of threat memories, compared to dorsal CA1.

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Sleep beliefs may shape behavior even when sleep itself doesn’t change. In an experimental study, Chu et al. told participants they had slept either well or poorly; those told they slept poorly behaved less prosocially on a behavioral task—not bc they became more overtly aggressive. buff.ly/rcOg3X4

LJMU Research Online

Ireland, J ORCID: 0000-0002-5117-5930 and Chu, S (2026) Can misinformation about sleep shape aggressive and prosocial behaviour. Journal of Aggression, Conflict and Peace Research. ISSN 1759-6599

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Sleep loss may change how we experience art! 🎨 In a controlled crossover study, Godinho et al. found that restricting sleep to 5.5 hours reduced ratings of both the beauty and likability of abstract artwork, with the effects mediated by reduced positive mood and greater sleepiness. buff.ly/X1kbaca

<em>Journal of Sleep Research</em> | ESRS Journal | Wiley Online Library

Sleep loss influences basic emotional and cognitive processes, but its impact on higher-order naturalistic cognition, such as aesthetic judgements, is less understood. The current study primarily…

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Closed-loop stimulation may improve memory through more than just boosting slow waves. Grimaldi et al. found that better retention tracked the balance of slow-oscillation vs delta coupling to spindles, along with ⬆️ parasympathetic activity—not simply stronger SO–spindle coupling. buff.ly/JyhmjGn

Acoustic enhancement of slow wave sleep improves memory retention by coordinating brain oscillatory rhythms and autonomic activity

Sleep plays a crucial role in memory consolidation. While the interaction between sleep oscillations and autonomic activity likely influences this process,

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A striking demonstration that sleep physiology can be manipulated in real time: Levitt et al found that closed-loop auditory stimulation timed to slow-wave peaks ⬆️ cerebrospinal fluid flow during NREM sleep, providing evidence for a causal link btwn slow waves & CSF dynamics! buff.ly/qLtjlWy

Closed-loop auditory stimulation in phase with slow waves during sleep enhances cerebrospinal fluid flow in humans

Sleep slow-wave neurofeedback inside the MRI scanner can drive large-scale cerebrospinal fluid flow.

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Digital CBT-I can expand access, but accessibility isn’t automatic. In a case study, Van Rossen et al. found sleep efficiency improved from 63% to 87%, while sound-based alarms and other treatment features created avoidable barriers for a deaf patient. Accessibility is key! buff.ly/HqqGxLT

Is Digital Cognitive Behavioral Therapy for Insomnia Accessible for th | NSS | Dove Medical Press

Highlighting unaccounted gaps in dCBT-I treatment adherence, by exploring the experience of a deaf individual engaging in a six-week dCBT-I program

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A great opportunity for early-career sleep and circadian researchers: applications are open for AASM Foundation’s Young Investigators Research Forum 2027. I was a past YIRF trainee and highly recommend it! Applications due Oct. 19: buff.ly/knCqdUZ

Young Investigators Research Forum - AASM Foundation

The AASM Foundation is committed to growing and supporting the pipeline of sleep scientists by investing in the research careers of new investigators through mentorship and grantsmanship training…

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A nice real-world look at the sleep–mood relationship: across 1,712 nights with home EEG, Pierson-Bartel et al. found later sleep onset predicted lower positive affect the next day. Sleep timing may matter for mood independently of how well we sleep. buff.ly/iryU8Qc

Sleep timing regulates mood: A multilevel-EEG study of daily life

Sleep and mood are homeostatically regulated systems essential for mental and physical health. Understanding how sleep timing and mood dynamically influence each other, and which individual traits mod...

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Can what we think about before sleep shape our dreams? Holder & @wamsleylab.bsky.social found that reactivating emotional autobiographical memories shifted subsequent dream emotion, but dreaming about those memories did not reduce overnight emotional reactivity. Sweet dreams! doi.org/10.1093/slee...

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This research demonstrates that reactivating remote emotional memories before sleep influences subsequent dream emotions. Notably, we found no evidence tha

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Postpartum sleep problems may be getting missed more often than we realize. Takenoshita et al found that 13% of adults met criteria for insomnia disorder 6 weeks postpartum, but only 2 of 20 cases had received a clinical evaluation highlighting a major gap in postpartum care doi.org/10.1007/s444...

Insomnia disorder at 6 weeks postpartum: a prospective study - Journal of Clinical Sleep Medicine

Purpose To estimate the prevalence of insomnia disorder and insomnia symptoms, explore risk factors for insomnia disorder, and characterize sleep at 6 weeks postpartum. Methods Following IRB…

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Interesting evidence that sleep-dependent memory processing may begin before we even fall asleep: Denis et al. found that theta activity during learning predicted later slow oscillation–spindle coupling during sleep, which in turn predicted better memory. doi.org/10.1371/jour...

Theta oscillations tag episodic memories for sleep-dependent consolidation

Why some experiences are retained while others fade remains a central question in memory research. This study shows that theta-band activity during learning marks memories for sleep-dependent consolid...

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Anderson et al found that greater EEG slowing during REM sleep was linked to worse global cognition and executive function in Lewy body disorders—and tracked dysfunction in cholinergic brain networks. An interesting example of sleep physiology as a potential biomarker www.nature.com/articles/s41...

Electroencephalographic slowing during REM sleep as a marker of cholinergic network dysfunction in Lewy body disorders - npj Parkinson's Disease

npj Parkinson's Disease - Electroencephalographic slowing during REM sleep as a marker of cholinergic network dysfunction in Lewy body disorders

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Frimpong et al. found that a single bout of moderate evening exercise helped protect declarative memory after sleep restriction—and the benefit was statistically mediated by more slow-wave sleep. A nice mechanistic link between exercise, sleep, and cognition. academic.oup.com/sleep/advanc...

Slow-Wave Sleep Mediates the Compensatory Effects of Acute Moderate-Intensity Exercise on Declarative Memory Deficits in Sleep Restriction

Here, we demonstrate that a single session of moderate-intensity evening exercise performed before a night of sleep restriction was associated with better

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Do et al. tested brief CBT-I in 219 women undergoing chemotherapy for breast cancer. Despite ongoing chemotherapy, CBT-I produced significantly > improvements in insomnia than comparison conditions; bright light therapy did not. Further support for benefits of CBT-I! jamanetwork.com/journals/jam...

Cognitive Behavior vs Bright Light Therapy for Insomnia in Women With Breast Cancer

This randomized clinical trial examines the effectiveness of cognitive behavior therapy for insomnia compared with bright light therapy for treating insomnia and fatigue symptoms in Australian women…

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