TRIDENT Preclinical Trials
@tridentpct.bsky.social
Multi-site, transformative preclinical evaluation of novel neurotherapeutics through a Government of Canada $24M New Frontiers In Research grant. Check out our website tridentpreclinicaltrials.org for more info or email info@tridentpreclinicaltrial.org!
Introducing the TRIDENT Data Hub! A centralized gateway to TRIDENT research datasets, metadata, and related resources, developed by the #TRIDENT Data Management & Sharing Team at the @douglasresearch.bsky.social CoBrA Lab. #NFRF #OpenScience TRIDENT Data Hub: data.tridentpreclinicaltrials.org
Happy #FluorescenceFriday! Amazing work by the @mind-western.bsky.social. This striking visualization highlights GFP (yellow) and SynP129 (magenta), providing a glimpse of aggregated alpha-synuclein in a Slick-H Cre STIP1 mouse model. 🧠 🔬
Marco A. Maximo Prado@maximoprado.bsky.social · 5d ago#fluorescencefriday a Slick-H Cre STIP1 mouse seeded with alpha synuclein preformed fibrils. GFP (cells presenting recombination) in yellow and SynP129 (marker of aggregated alpha synuclein) magenta by the @mind-western.bsky.social team
🎥 Faculty Spotlight: Dr. Taylor Schmitz Dr. Taylor Schmitz, TRIDENT's Mouse Core Lead, discusses his current research, reflects on his journey as a researcher, and shares advice for aspiring research trainees. #NFRF #TRIDENT #FacultySpotlight #Neuroscience #Research #WesternU youtu.be/BLhvgMAcXts
Dr. Taylor Schmitz Faculty Spotlight
YouTube video by TRIDENT Preclinical Trials
youtu.be
🎉 Congratulations to our #TRIDENT imaging partner, @cfmm.bsky.social, on this investment from @braincanada.bsky.social and @westernu.ca. This expanded national MRI platform will strengthen access to world-leading neuroimaging infrastructure, accelerating collaboration and discovery across Canada. 👏🤩
Western University@westernu.ca · 3w ago🧠 Big boost for brain research: Brain Canada is investing $1.4M, matched by #WesternU, giving more researchers across Canada access to Western’s national MRI platform to tackle complex brain health challenges. @braincanada.bsky.social
🚀 HQP Spotlight: David Roper, RA, #TRIDENT Data Management & Sharing Core, CoBrA Lab, @douglasresearch.bsky.social. David helps advance our collaboration and open science aims by supporting accessible, reproducible research data across TRIDENT. #NFRF🎥 Learn more: www.youtube.com/watch?v=L1x7...
HQP Spotlight: David Roper, RA, TRIDENT Data Management and Sharing Core, Douglas Research Centre
YouTube video by TRIDENT Preclinical Trials
youtube.com
🔦 Spotlight on the #TRIDENT Data Mgmt & Sharing Core, CoBrA Lab at the @douglasresearch.bsky.social. Led by Dr. Mallar Chakravarty, the team combines computational neuroscience with animal and human studies to advance preclinical neurotherapeutics and open science. 🔗Learn more: www.cobralab.ca!
Accueil | CoBrALab
cobralab.ca
Happy to see our partnering research institution @camhnews.bsky.social, lead Sex-Based Analysis+ researcher @liisagalea.bsky.social and expert team at #AAIC2026! Check out their talks below. 👇😍🐁🧠https://aaic.alz.org/program/schedule.asp
Liisa Galea@liisagalea.bsky.social · 4w agoUp next for the Galea lab at #AAIC26 are 4 posters and 1 talk. Please join us to talk about sex, menopause and APOE4 in mouse models and women! @matejaperovic.bsky.social @sandracorvi.bsky.social
🔬Great science doesn't happen in isolation.🧠🌎We are proud to see #TRIDENT leader Ravi Menon featured in @westernu.ca's #theimpactproject, speaking to the power of technology + team collaboration, also key elements of TRIDENT!👏 @northernthrux.bsky.social www.theimpactproject.ca/stories/ravi...?
How technology and teamwork power medical breakthroughs | The Impact Project
Join us as we uncover what it takes to make positive change in our world – featuring Ravi Menon, Neurophysicist, Professor, Schulich School of Medicine & Dentistry, Western University.
theimpactproject.ca
One of the best parts of research is the people. Great to connect with our incredible colleagues yesterday at the @schulichmeddent.bsky.social Staff and Faculty Summer BBQ. Here's to continuing to build partnerships, support each other, + advance neuroscience together! 💜🧠 @cfmm.bsky.social #TRIDENT
🧠 Heading to #ISSCR2026? Be sure to catch #TRIDENT's valued collaborators Dr. Tom Durcan and Anna Franco Flores presenting a poster Wednesday, July 8 from 5:15–6:30 PM, entitled "From PDFs to Videos: Making iPSC Workflows Accessible Through Outreach." Great work folks! 🔬👇🤩 www.isscr2026.org
ISSCR 2026
An international gathering of the brightest minds in stem cell research and regenerative medicine across disciplines. Join us for the 2026 ISSCR Annual Meeting 8-11 July 2026 in Montréal, Canada.
isscr2026.org
🍁 Happy Canada Day! 🇨🇦 Today we celebrate our incredible pan-Canadian team who make #TRIDENT possible. Proudly supported by the Government of Canada's New Frontiers in Research Fund, we're building a stronger future through worldclass research impact and innovation. #NFRF youtu.be/dfi8Fu29BQI?...
TRIDENT: Strengthening Canada's Path to Brain Health Innovation
YouTube video by TRIDENT Preclinical Trials
youtu.be
👀 ICYMI Monday: Meet Kruti Joshi from our Imaging Team, one of the many talented HQP helping drive innovation across our collaborative research ecosystem at #TRIDENT. 🤝🔬🤩 🎥 #NFRF #Collaboration #HQP #Neuroscience
TRIDENT Preclinical Trials@tridentpct.bsky.social · 2mo agoAt #TRIDENT, our greatest strength is our people. 🤝🔬🤩 We're excited to spotlight Kruti Joshi from our Imaging Team, one of the many talented HQP helping drive innovation across our collaborative research ecosystem. 🎥 #NFRF #Collaboration #HQP #Neuroscience www.youtube.com/watch?v=GSc_...
Turning noisy data into clearer discoveries. This #FluorescenceFriday post shows how the @mind-western.bsky.social Platform is developing open science tools to remove imaging artifacts from light-sheet microscopy, helping researchers generate cleaner, more reliable 3D brain images. Great job team!🧠
Marco A. Maximo Prado@maximoprado.bsky.social · last mo.#fluorescencefriday pre and post processed images to remove artifacts due to lightsheet imaging. The @mind-western.bsky.social platform with the leadership of @neuroak.bsky.social is developing new open science tools to process, register, segment and quantify 3D volumetric images for the 🐁 🧠
We're thrilled to share this video capsule produced in collaboration with @theneuro.bsky.social EDDU, showcasing #TRIDENT's overarching vision and goals, and highlights the key role the EDDU has played in bringing that vision to life. #neuroscience #collaboration #KMb #NFRF 📽️🧠🔬 youtu.be/3wKA2JhdXtg
TRIDENT x EDDU
YouTube video by TRIDENT Preclinical Trials
youtu.be
🧠🔬 Shoutout to TRIDENT Imaging Team member Kruti Joshi, who presented a poster at the 2026 Robarts Research Retreat today! Proud to see our incredible students sharing discoveries and building new scientific connections. 👏 #TRIDENT #HQP #Neuroscience #fMRI #NFRF @schulichmeddent.bsky.social
Congrats to @cfmm.bsky.social on 30 years of imaging discovery and innovation! 🎉🧠 #TRIDENT is proud to partner with this world-leading, made-in-Canada facility and thrilled to see CFMM receive its 3rd consecutive Platform Support Grant from @braincanada.bsky.social. news.westernu.ca/2026/06/west...
Western CFMM imaging discovery hits 30 years - Western News
Western's Centre for Functional and Metabolic Mapping houses advanced suites of imaging technology, allowing researchers to study organs in detail.
news.westernu.ca
TGIFF! Happy #Fluorescencefriday everyone...tiny connections, big insights, below! 👇🧠🐁
Marco A. Maximo Prado@maximoprado.bsky.social · 2mo ago#fluorescencefriday the last event.fourwaves.com/iscm2026/pages inspired posting Labeling for VAChT in the hippocampus. It is hard to look at synapses in the whole cleared 🧠 even in 🐁 but I think we got enough signal when we compare to KO tissue.
🧠Transformative, collaborative #NFRF research in action! Congrats to the #TRIDENT Marmoset Team at @westernu.ca and @mcgill.ca on this new preprint, demonstrating how team science and specialized models are advancing our understanding of Parkinson's disease. 🌎🗞️🎉 www.biorxiv.org/content/10.6...
α-synuclein pathology drives multi-scale reorganization of fronto-limbic networks and cognitive flexibility in the common marmoset
Understanding how α-synuclein misfolding and spreading affect brain systems is central to synucleinopathy research, yet evidence from primate models remains limited. Here, we combined histology, awake...
biorxiv.org
From #TRIDENT to Bordeaux! ✈️🧠 Congrats to one of our valued @westernu.ca HQP Kruti Joshi (also spotlighted this week!) on presenting her work via @ohbmofficial.bsky.social. We love seeing our team connect, collaborate and showcase their research with the global neuro community! #OHBM2026 #HQP #NFRF
The Organization for Human Brain Mapping@ohbmofficial.bsky.social · 2mo agoJoin us for the #OHBM2026 Poster Reception! 🧠🤝 📅 June 16 🕓 17:00–18:00 📍 Exhibition Hall 1 Enjoy great science, conversation, and community—see you there! 🔬✨
At #TRIDENT, our greatest strength is our people. 🤝🔬🤩 We're excited to spotlight Kruti Joshi from our Imaging Team, one of the many talented HQP helping drive innovation across our collaborative research ecosystem. 🎥 #NFRF #Collaboration #HQP #Neuroscience www.youtube.com/watch?v=GSc_...
An Interview with Kruti Joshi, TRIDENT Imaging Core
YouTube video by TRIDENT Preclinical Trials
youtube.com
ICYMI Monday...a fantastic video about our #TRIDENT partner @cfmm.bsky.social.📽️ 👇Curiosity built it. Innovation sustained it. Discovery continues to drive it. Congratulations to CFMM on 30 years of advancing imaging science and unlocking the secrets of the brain. 🎉🌎 www.youtube.com/watch?v=LzKK...
From Curiosity to Discovery: Western’s CFMM at 30
YouTube video by Schulich School of Medicine & Dentistry
youtube.com
It's hard not to be amazed when an entire mouse brain can be visualized in such stunning detail. 🧠🔬Thanks to the world-class light-sheet microscopy infrastructure at @mind-western.bsky.social, we can explore brain architecture and reveal insights once impossible to see. 👀😍 👇#fluorescencefriday
Marco A. Maximo Prado@maximoprado.bsky.social · 2mo ago#fluorescencefriday The 18th cholinergic meeting is coming up in Montreal event.fourwaves.com/iscm2026/reg... so ChAT labelling to look at the distribution of basal forebrain cholinergic neurons in @lifecanvastech.bsky.social SHIELD-cleared 🧠 Courtesy @mind-western.bsky.social
🌈 Diverse collaboration. Stronger discovery. At #TRIDENT, we know that innovation thrives when diverse perspectives come together. Happy Pride Month from the TRIDENT team. 🧠❤️ #PrideMonth #Neuroscience #TeamScience #Collaboration #NFRF
🧠 #FluorescenceFriday: Relationship status: Seeing plaques, but also talking to blood vessels. 💘🔬 We can't get enough of the incredible imaging from the MIND team, partnering platform of #TRIDENT 👇 🤩 . For more information check out their website 🔗 www.mind-western.ca.
Marco A. Maximo Prado@maximoprado.bsky.social · 2mo ago#fluorescencefriday Whole 🧠 microglia (cyan) distribution in an Alzheimer’s disease 🐁 model shows that microglia like amyloid plaques (magenta) but also enjoy clinging to blood vessels (yellow). Courtesy from the @mind-western.bsky.social team showing different levels of detail for the hippocampus
🧲🌎Congratulations to the incredible team at the Centre for Functional & Metabolic Mapping on 30 years of innovation and discovery. We're so proud to partner with a facility that's helping bring the future of brain research into focus! #TRIDENT #CFMM 🎉 www.schulich.uwo.ca/about/news-e...
Western’s CFMM marks 30 years of imaging discovery - Schulich School of Medicine & Dentistry - Western University
Researchers have transformed understanding of the brain, healthy aging and disease.
schulich.uwo.ca
Mark your calendars to join and learn from a seriously cool world-renowned researcher @maximoprado.bsky.social! Thank you @stressmarq.bsky.social for hosting this event. 🎉 🙏 🔬 🌎
StressMarq Biosciences@stressmarq.bsky.social · 2mo ago🌐 Live & On-Demand Webinar 🌐 🗓️ June 11 @ 8 AM PT Next‑generation humanized mouse models offer deeper insight into the mechanisms driving cognitive dysfunction in #neurodegeneration. 🔗 Discover the science & impact of integrated experimental platforms - Register now: https://bit.ly/4n8CzUp
Representing #TRIDENT at the Alzheimer Society Southwest Partners IG Wealth Management 2026 Walk for Alzheimer's! Great turnout for an incredible event to connect with community and help fund crucial programs and services for people with dementia, their caregivers and family!
🔬🧠 Red meets white under the lights: proof that neuroscience has some of the brightest interactions around. #FluorescenceFriday ✨Great job to @arashsalah.bsky.social and the @mind-western.bsky.social team, incredible partnering platform of #TRIDENT.
Marco A. Maximo Prado@maximoprado.bsky.social · 2mo ago#fluorescencefriday when microglia (red) meets amyloid plaques (white). By the @mind-western.bsky.social team and @arashsalah.bsky.social