Congratulations to Roy Jung on leading our new paper @insight.jci.org ! Esco2 loss disrupts vascular development and reveals hidden isoform dysregulation linked to pathological EndMT in Roberts syndrome. doi.org/10.1172/jci.... @umasschan.bsky.social @umassmedicine.bsky.social

Outstanding collaborative work by Tim Cashman et al @trivedilab.bsky.social - Epigenetic dysregulation of energy homeostasis drives aortic valve stenosis that is treatable with metformin insight.jci.org/articles/vie... @umasschan.bsky.social @umassmedicine.bsky.social @jci-insight.bsky.social