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This paper is now online at @currentbiology.bsky.social. This marks the end of my postdoc and I’ll be joining @imperiallifesci.bsky.social as Imperial College Research Fellow in October! 🎊 🥳🍾 www.cell.com/action/showP...

Ethan (Chee Kiang) Ewe@ethanewe.bsky.social · 12mo ago

🔥my latest paper from @odedrechavi.bsky.social lab🔥 we found small RNAs act across tissues to regulate fertlity in C. elegans 🪱. Surprisingly, we also found that O2-sensing neurons inhibit germline maintenance. Follow along our journey👇https://www.biorxiv.org/content/10.1101/2025.08.07.669182v1

So proud of our new publication in @currentbiology.bsky.social A wonderful collaborative effort spearheaded by the amazing @ethanewe.bsky.social from @odedrechavi.bsky.social group, with the germline side expertly done by our very own Hanna Achache. bsky.app/profile/oded...

Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress

Ewe et al. demonstrate that neuronal small RNAs can modulate germline development under heat stress in Caenorhabditis elegans. They further show that disrupting the oxygen-sensing neural circuit promo...

cell.com

Oded Rechavi@odedrechavi.bsky.social · last mo.

Check out Ethan's new paper on how the brain helps protect fertility from heat-induced damage, now out in @currentbiology.bsky.social! Ethan will be opening his own lab in London in a few months - I highly recommend joining him (students/post-docs/technicians) www.sciencedirect.com/science/arti...

Check out Ethan's new paper on how the brain helps protect fertility from heat-induced damage, now out in @currentbiology.bsky.social! Ethan will be opening his own lab in London in a few months - I highly recommend joining him (students/post-docs/technicians) www.sciencedirect.com/science/arti...

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

So excited about our recent 📜in @natcomms.nature.com In short, we found 3 lncRNAs that ensure oocyte differentiation by condensing FBF-2, a protein that prevents meiosis entry. And yes, a homologous mechanism probably exists in mammals. #fertility #lncRNA #meiosis nature.com/articles/s41...

Three lncRNAs promote PUM protein condensation and germline differentiation - Nature Communications

RNA-binding FBF proteins control germline stem cell differentiation. Here, the authors show that three long non-coding RNAs bind, condense, and thus inhibit FBFs to promote the transition of germline stem cells into meiosis.

nature.com

One of the best collaborations we ever had. Brainstorming with ‪@ethanewe.bsky.social‬ whenever a new result came up, was so uplifting and we felt like we boldly go where no one has gone before. Top tier research institutions: grab him while you can!

Ethan (Chee Kiang) Ewe@ethanewe.bsky.social · 12mo ago

In summary, we think that low oxygen levels signal reproductive permissive environments and promote germline maintenance. This neurons-to-germline communication may be super important for enabling animals to sense, adapt, and propagate in fluctuating environments. 🔥🍂🍎🪱

WOoo! Hot pre-print alert! 🔥 Check out our new story - We describe evidence that "neuronal oversight" of germline small RNAs prevents sterility and allows lab-domesticated C. elegans to reproduce when temperatures go up (1/2) www.biorxiv.org/content/10.1...

‪So proud we could take part in this amazing project! Germline/meiosis crowd, you must check this out. A whole new dimension of non-cell autonomous control on gametogenesis. Also, triple shoutout for @ethanewe.bsky.social . A great PI on the way #meiosis #germline #ncRNA

Oded Rechavi@odedrechavi.bsky.social · 12mo ago

WOoo! Hot pre-print alert! 🔥 Check out our new story - We describe evidence that "neuronal oversight" of germline small RNAs prevents sterility and allows lab-domesticated C. elegans to reproduce when temperatures go up (1/2) www.biorxiv.org/content/10.1...

After 10 years of work, a complete telomere-to-telomere gap-free genome for C. elegans finally exists: it has 106 Mb rather than the textbook 100.3 Mb, and up to 366 additional genes. genome.cshlp.org/content/35/8...

We go to so many meetings and conferences that most just blend into our memory. But rare ones stand out and truly change the way we think and do science. 👇This was one of those that will stay a part of me.

Oded Rechavi@odedrechavi.bsky.social · last yr.

🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...

A kind invitation by the Cell Biology Department of @charlesuni.cuni.cz brought Israeli scientist stranded in Prague after the #TCTeAC to do what we love best - participate in exciting scientific discussions!

@barakrotblat.bsky.social : "close you eyes and think about being alive". Me: "is it worth living in glucose starvation?" #TCTeAC

@tzurlab.bsky.social Yonathan Tzur at Woodstock Night Science conference #TCTEAC

#TCTeAC

Balance as a key in life and our biological question. Yonatan Tzur #TCTeAC

And now Ahmed Elewa with a beautiful development biology talk

And here it starts: @woodstocknightsci.bsky.social #TCTeAC #theconferencetoendallconferences

Another great example of the pivotal role of MAPK in reproduction

Soni Lacefield@lacefieldlab.bsky.social · last yr.

Super excited to post our new publication on the role of MOS/MAPK signaling in maintaining the egg transcriptome. Great collaboration with Britt Goods lab! rep.bioscientifica.com/view/journal...

With @gazitroi.bsky.social on our way to #theconferencetoendallconferences

In this conference we couldn't care less where you published your story because 1. we only care if it's interesting and good and 2. participants will discuss unpublished work

Oded Rechavi@odedrechavi.bsky.social · last yr.

Who does that? We rented a train JUST for the conference, that will take the participants from Prague to the woods of Bohemia. There'll be talks ON THE TRAIN. In Prague we'll have 5 locations with different atmospheres. #theconferencetoendallconferences Register now: woodstock.img.cas.cz

With more research in this direction the former may not be so certain!

Björn Schumacher@bjornschumacher.bsky.social · 2y ago

"Nothing in life is certain except death, taxes and the second law of thermodynamics", the latter causing the first through aging (doi.org/10.1038/s435...) and taxes should better be devoted to find out what we can do about it.

GIF where you're from

a falafel token is being launched into the sky

ALT: a falafel token is being launched into the sky

media.tenor.com

Javier Apfeld@javierapfeld.bsky.social · 2y ago

GIF where you're from

🔊 We are recruiting PhD students and Postdocs! We are seeking highly motivated, talented, and creative researchers, with strong background in cell and developmental biology, who are looking to spearhead original interdisciplinary investigations, addressing overlooked biology. 1/5

The deadline to apply to our Ph.D. program is two weeks away. Apply by December 1st!

The Allard lab@allard-lab-ucla.bsky.social · 2y ago

It is grad school application season! If you are interested in studying Gene-Environment Interactions and Toxicology at the #1 public university, consider applying to the UCLA Environmental and Molecular Toxicology Ph.D. program! 👇

💕 6 tools for illustrating your scientific works! (FREE) 👉Read my Article on Medium here: medium.com/@vespinozag/... #genomic #chemistry #Academic #DataVisualization #postdoc #MachineLearning #DataScience #Bioinformatics #PhD #health #Python #Statistics #Programing #neuroscience #biology #science

I would like to thank all the friends and colleagues checking in with me.

mRNA self-assemble into same-sequence condensates in C. elegans oocytes www.cell.com/cell/fulltex...