Tzviya Zeev-Ben-Mordehai
@tzviyazbm.bsky.social
The cellular structural biology of fertilization group
Very happy that NWO supports this major upgrade of our national EM infrastructure. It is great that this initiative got broad support all over NL, and it will EMPower fantastic science - looking forward to that! www.uu.nl/en/news/33-m...
33 million euro investment for national electron microscope facility EMPower
A major new national facility for electron microscopy, called EMPower, has been awarded to a consortium of Dutch universities and medical centers. EMPower aims to pave the way for major discoveries im...
uu.nl
Happy to see this out :) How close does single-particle cryo-EM get to in situ structure determination? In this review, @tzviyazbm.bsky.social and I explore recent examples of studies that we believe push the boundaries of what's possible. #cryo-EM
cryoEM papers@cryoempapers.bsky.social · 10mo agoCryo-EM single-particle analysis expanding towards increasingly native samples pubmed.ncbi.nlm.nih.gov/41129371/ #cryoEM
I am happy our recent study on the human sperm head-tail junction is now online. We find that SUN5 form an hexagonal lattice at the nuclear membrane, rationalising how mutations in SUN5 lead to infertility. Great work of @cryonas.bsky.social ! www.biorxiv.org/content/10.1...
SUN5 forms a regular protein lattice reinforcing the sperm head-tail junction
Linker of nucleo- and cytoskeleton (LINC) complexes reside in the nuclear envelope, the double-membrane surrounding the nucleus, where they establish a physical bridge between nucleus and cytoplasm. L...
biorxiv.org
Latest preprint from the lab, many years in the making! By combining #cryoEM with #AlphaFold3 modelling, we propose that norovirus NS3 forms a transmembrane RNA translocase. This could have big implications for our understanding of viral replication & assembly (🧵) www.biorxiv.org/content/10.1...
Amazing meeting amongst great colleagues and friends 🫶🏻. Looking forward to ETW 2027 in Germany 🇩🇪
I am honoured to receive a Vici grant from the Dutch Research Council to study sperm functional maturition at the female reproductive tract and to study how sperm establish interaction with an egg www.uu.nl/en/news/nine...
Nine Utrecht-based researchers receive Vici-grant
The Dutch Research Council (NWO) has awarded Vici grants to nine Utrecht researchers.
uu.nl
New year, new publication, new social media platform www.nature.com/articles/s41...
Structural diversity of axonemes across mammalian motile cilia - Nature
Cryoelectron microscopy, cryoelectron tomography and proteomics are used to resolve the 96-nm modular repeat of axonemal doublet microtubules from both sperm flagella and epithelial cilia of the ovidu...
nature.com