A big thank you to @drmichelaleocadi.bsky.social and @hdyofeed.bsky.social for organising such a meaningful event today! If you’re able, please consider donating to support this important cause. Every contribution makes a difference - hdyo.enthuse.com/pf/huntingto...

🏃‍♀️ Run 4 HDYO Olivia (Liv) Martinez Scholarship Fund– 5K Charity Run/Walk at Battersea Park, July 4th 2026

After the success of 2025, where we raised more than £3000 thanks to generous donations, come join us again for a 5K run or walk to raise awareness of Huntington’s Disease and support the amazing work

hdyo.enthuse.com

Second 'RUN 4 HDYO' in honour of the life and legacy of Liv, while raising funds for the Olivia (Liv) Martinez Scholarship Fund to help more young people attend the #HDYO Congress in 2027 @hdyofeed.bsky.social @ucl-hd.bsky.social

The current HD-ISS doesn't incorporate wet biomarkers. Dr. Mena Farag discusses the promising results of proenkephalin and other biomarkers to help monitor the earliest stages of HD before the onset of motor symptoms. https://loom.ly/j3VrGFs

So much @ucl-hd.bsky.social love at my leaving do! Thank you to everyone who made the last three years of my PhD journey such a joy. @uclbrainscience.bsky.social @uclqsion.bsky.social

Signing off from the LWENC with this wonderful team. 3 years of teamwork, learning and shared commitment to our #HD clinical trials @ucl-hd.bsky.social @uclqsion.bsky.social - thank you all for making it so special.

Discovery of disrupted sustained attention and altered functional connectivity in far‐from‐onset Huntington's disease gene‐expanded young adults alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Discovery of disrupted sustained attention and altered functional connectivity in far‐from‐onset Huntington's disease gene‐expanded young adults

BACKGROUND Cognitive impairments are a hallmark of Huntington's disease (HD). METHODS Seventy-one participants (43 HD gene-expanded [HDGE], 28 healthy controls) from the HD-Young Adult Study at tw...

alz-journals.onlinelibrary.wiley.com

Our featured article for January is a Review on somatic CAG expansions and the potential for therapeutic interventions, from Sarah Tabrizi and colleagues. Free to read here: rdcu.be/eXFmV

Huntington disease: somatic expansion, pathobiology and therapeutics

Nature Reviews Neurology - Genome-wide association studies have identified genetic modifiers, mostly DNA repair genes, that significantly influence the onset and progression of Huntington disease,...

rdcu.be

Congratulations @drmfarag.bsky.social from @ucl-hd.bsky.social! 👏 @ukdri.ac.uk @uclqsion.bsky.social @uclbrainscience.bsky.social @uclnews.bsky.social @ucl.ac.uk 🔗 www.ucl.ac.uk/brain-scienc...

Dr Mena Farag awarded a UK DRI Recognition Prize 2025

We're delighted that Dr Mena Farag (UCL Queen Square Institute of Neurology) was awarded the UK DRI PhD Prize on 9th December 2025 at Connectome 2025.

ucl.ac.uk

"For the first time I thought, this is a real breakthrough... I’d had this sword of Damocles over me, always thinking, when’s the disease going to strike?” Amanda Staveley shares what the pioneering Huntington's breakthrough at @uclqsion.bsky.social means to her.

Amanda Staveley: Newcastle, my brain disease and the doctor who gave me hope

The football financier who helped the Saudis buy Newcastle United has Huntington’s disease, a hereditary terminal condition with debilitating symptoms. Now a new treatment has been pioneered by a British...

thetimes.com

We're looking back on just some of the incredible scientific breakthroughs that came out of our Faculty this year. First up... Researchers at @uclqsion.bsky.social made global headlines by successfully treating Huntington’s disease for the first time. www.ucl.ac.uk/news/2025/se...

We're delighted that Professor Sarah Tabrizi (@uclqsion.bsky.social) is part of Nature’s 10, a list of people who shaped science in 2025. Her team's global trial at @ucl-hd.bsky.social showed a new Huntington’s treatment could slow progression by 75%.

‘Giant step forward’ for Huntington’s — the scientist behind the first gene therapy

Sarah Tabrizi is part of Nature’s 10, a list of people who shaped science in 2025.

nature.com

I am incredibly honoured to share that I have been awarded the @ukdri.ac.uk PhD Prize at #Connectome 2025! @ucl-hd.bsky.social @uclqsion.bsky.social @uclbrainscience.bsky.social

Open Access UCL Research: Huntington's disease clinical trials update: October 2025 discovery.ucl.ac.uk/id/eprint/10...

🏆 1/ Professor Sarah Tabrizi, Director of the UCL Huntington’s Disease Centre (@ucl-hd.bsky.social), was awarded the British Neuroscience Association Outstanding Contribution to Neuroscience Award for 2025, the association’s top annual prize. www.ucl.ac.uk/news/2025/no...

Pioneering UCL Huntington’s researcher wins major neuroscience award

Professor Sarah Tabrizi, Director of the UCL Huntington’s Disease Centre, has been awarded the British Neuroscience Association (BNA) Outstanding Contribution to Neuroscience Award for 2025, the…

ucl.ac.uk

Check out the October 2025 edition of the #HD Clinical Trials Update, now published in the Journal of Huntington's Disease and available online! 🔗 journals.sagepub.com/doi/10.1177/... @profwild.bsky.social @ucl-hd.bsky.social @uclqsion.bsky.social @uclbrainscience.bsky.social

Sage Journals: Discover world-class research

Subscription and open access journals from Sage, the world's leading independent academic publisher.

journals.sagepub.com

🎉 Congratulations to Prof. Sarah Tabrizi ( @ucl-hd.bsky.social, @uclqsion.bsky.social) who has won the prestigious @britishneuro.bsky.social prize for her outstanding contributions to neuroscience! www.ucl.ac.uk/news/2025/no...

Congratulations to Professor Sarah Tabrizi @ucl-hd.bsky.social @uclqsion.bsky.social on earning the @britishneuro.bsky.social Outstanding Contribution to Neuroscience Award, for excellence and leadership in UK neuroscience and recognising her transformative impact on Huntington's disease research

Pioneering UCL Huntington’s researcher wins major neuroscience award

Professor Sarah Tabrizi, Director of the UCL Huntington’s Disease Centre, has been awarded the British Neuroscience Association (BNA) Outstanding Contribution to Neuroscience Award for 2025, the assoc...

ucl.ac.uk

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...

Amid this week’s huge milestone in #HD treatment, I’m excited to share part of my PhD thesis + our paper published today in @movedisorder.bsky.social on CSF #PENK predicting striatal atrophy decades before clinical motor diagnosis 🔗 movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abu...

movementdisorders.onlinelibrary.wiley.com

Amazing news from @ucl-hd.bsky.social @ucl.ac.uk hitting the headlines this week. A new form of gene therapy has successfully treated Huntington's Disease for the first time ever, slowing the disease by 75%. This university research is changing lives. Read more on BBC News ⬇️

UCL Faculty of Brain Sciences@uclbrainscience.bsky.social · 11mo ago

🧵 BREAKING: Gene therapy shows promise in slowing Huntington’s disease progression. A major milestone in neurodegenerative disease research. @uclqsion.bsky.social @ucl-hd.bsky.social www.bbc.co.uk/news/article...

🧵 BREAKING: Gene therapy shows promise in slowing Huntington’s disease progression. A major milestone in neurodegenerative disease research. @uclqsion.bsky.social @ucl-hd.bsky.social www.bbc.co.uk/news/article...

Huntington's disease successfully treated for first time

One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.

bbc.co.uk

Join us on 6 October for the Ferrier Prize Lecture. Professor Gillian Bates FRS (@ucl-hd.bsky.social) will present how the Bates lab has been unravelling the molecular basis of Huntington’s disease: royalsociety.org/science-even...

Important paper on accessible biomarkers from @hob-lab.bsky.social. Well done Annabelle Coleman @drl-bo.bsky.social and all.

UCL Huntington’s Disease Centre@ucl-hd.bsky.social · last yr.

New paper from the @hob-lab.bsky.social just published in Journal of Neurology. A step toward more accessible biomarker testing 🩸 link.springer.com/article/10.1... @drl-bo.bsky.social @uclbrainscience.bsky.social @uclqsion.bsky.social

New paper from the @hob-lab.bsky.social just published in Journal of Neurology. A step toward more accessible biomarker testing 🩸 link.springer.com/article/10.1... @drl-bo.bsky.social @uclbrainscience.bsky.social @uclqsion.bsky.social

Evaluating finger-prick blood collection for remote quantification of neurofilament light in neurological diseases - Journal of Neurology

Promising blood-based biomarkers of neuropathology have emerged with potential for therapeutic development and disease monitoring. However, these tools will require specialist tertiary services for in...

link.springer.com

Super fun first 5K #RUN4HDYO! 🏃 💨 🏃‍♀️‍ Over £2500 raised for the Olivia (Liv) Martinez Scholarship Fund for HDYO - honouring an amazing ambassador I met at #HDYO Congress in Glasgow in 2023. Liv's kindness and passion touched so many. @ucl-hd.bsky.social @uclqsion.bsky.social

A series of digital tests carried out via a smartphone app could enhance the detection of disease progression in #HuntingtonsDisease and improve the efficiency of clinical trials, finds research led by scientists at @uclqsion.bsky.social @ucl-hd.bsky.social and Roche including @profwild.bsky.social

Smartphone tests could accelerate drug development for Huntington’s disease

A series of digital tests, carried out via a smartphone app, could enhance the detection of disease progression in Huntington’s disease and improve the efficiency of clinical trials, finds research le...

ucl.ac.uk

What is HDClarity?🧵 HDClarity is a longitudinal open-ended observational study. The main objective of the study is to collect high-quality cerebrospinal fluid samples for longitudinal evaluation of biomarkers and pathways which will enable the development of novel treatments for #HuntingtonsDisease

Check out the March 2025 edition of the #HD Clinical Trials Update, now available online in the Journal of Huntington's Disease @profwild.bsky.social 🔓 Open access link: journals.sagepub.com/doi/10.1177/... @ucl-hd.bsky.social @uclbrainscience.bsky.social @uclqsion.bsky.social

Hot off the press! Check out the second edition of the @ehdn-news.bsky.social Imaging Working Group (#iWG) newsletter! #HD #neuroimaging @drmichelaleocadi.bsky.social @rachiscahill.bsky.social @nicolahobbs.bsky.social ehdn.org/wp-content/u...

UCL HD Centre @ucl-hd.bsky.social celebrating #HDGratitudeDay. Thanks to all the families and researchers around the world who together are trying to improve lives for people with Huntington’s disease.